hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00011.1
Complex Portal: CPX-24443
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MAP3K3 | Mitogen-activated protein kinase kinase kinase 3 (EC 2.7.11.25) (MAPK/ERK kinase kinase 3) (MEK kinase 3) (MEKK 3) | 5 | UniProt NCBI |
| ABL1 | Tyrosine-protein kinase ABL1 (EC 2.7.10.2) (Abelson murine leukemia viral oncogene homolog 1) (Abelson tyrosine-protein kinase 1) (Proto-oncogene c-Abl) (p150) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04722 | 0.000804719987643 | 1.0 | MAP3K3 ABL1 | Neurotrophin signaling pathway |
| WP:WP437 | 0.00438235873998 | 1.0 | MAP3K3 ABL1 | EGF EGFR signaling pathway |
| CORUM:2811 | 0.0499419797295 | 0.5 | ABL1 | BRCA1-cABL complex |
| CORUM:7580 | 0.0499419797295 | 0.5 | MAP3K3 | MAP2K4-MAP3K3-NBR1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MAP3K3 | ABL1 | 0.979 | 0.098 | hein_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| MAP3K3 | huMAP3_00011.1 huMAP3_03708.1 huMAP3_08523.1 huMAP3_10808.1 huMAP3_10861.1 huMAP3_12897.1 |
| ABL1 | huMAP3_00011.1 huMAP3_08523.1 huMAP3_10861.1 huMAP3_12717.1 |