hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00030.1
Complex Portal: CPX-16200
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CRTC2 | CREB-regulated transcription coactivator 2 (Transducer of regulated cAMP response element-binding protein 2) (TORC-2) (Transducer of CREB protein 2) | 5 | UniProt NCBI |
| NUMBL | Numb-like protein (Numb-related protein) (Numb-R) | 5 | UniProt NCBI |
| CRTC3 | CREB-regulated transcription coactivator 3 (Transducer of regulated cAMP response element-binding protein 3) (TORC-3) (Transducer of CREB protein 3) | 5 | UniProt NCBI |
| EPN2 | Epsin-2 (EPS-15-interacting protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9707616 | 0.008795277704 | 0.5 | CRTC2 CRTC3 | Heme signaling |
| REAC:R-HSA-2151201 | 0.0115164156767 | 0.5 | CRTC2 CRTC3 | Transcriptional activation of mitochondrial biogenesis |
| REAC:R-HSA-400253 | 0.0186613511621 | 0.5 | CRTC2 CRTC3 | Circadian Clock |
| REAC:R-HSA-1592230 | 0.0371865475195 | 0.5 | CRTC2 CRTC3 | Mitochondrial biogenesis |
| KEGG:05166 | 0.0480473295333 | 0.5 | CRTC2 CRTC3 | Human T-cell leukemia virus 1 infection |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CRTC2 | CRTC3 | 0.994 | 0.086 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| CRTC2 | EPN2 | 0.987 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | ||
| CRTC3 | EPN2 | 0.984 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | ||
| NUMBL | EPN2 | 0.981 | hein_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only | ||
| CRTC2 | NUMBL | 0.974 | 0.132 | hein_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| NUMBL | CRTC3 | 0.649 | 0.128 | hein_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only |
Related Complexes