hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00078.1
Complex Portal: CPX-11789
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TEX35 | Testis-expressed protein 35 | 5 | UniProt NCBI |
| BORCS8 | BLOC-1-related complex subunit 8 (MEF2B neighbor) | 4 | UniProt NCBI |
| BORCS5 | BLOC-1-related complex subunit 5 (Loss of heterozygosity 12 chromosomal region 1) (Myristoylated lysosomal protein) (Myrlysin) | 5 | UniProt NCBI |
| BLOC1S1 | Biogenesis of lysosome-related organelles complex 1 subunit 1 (BLOC-1 subunit 1) (GCN5-like protein 1) (Protein RT14) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7545 | 3.92798604902e-08 | 0.75 | BORCS8 BORCS5 BLOC1S1 | BORC complex |
| GO:0099078 | 2.15253635486e-05 | 0.75 | BORCS8 BORCS5 BLOC1S1 | BORC complex |
| GO:0062196 | 2.15253635486e-05 | 0.75 | BORCS8 BORCS5 BLOC1S1 | regulation of lysosome size |
| GO:0098574 | 6.34131776058e-05 | 0.75 | BORCS8 BORCS5 BLOC1S1 | cytoplasmic side of lysosomal membrane |
| GO:0051036 | 8.45465618902e-05 | 0.75 | BORCS8 BORCS5 BLOC1S1 | regulation of endosome size |
| GO:0097494 | 0.000261258639543 | 0.75 | BORCS8 BORCS5 BLOC1S1 | regulation of vesicle size |
| GO:0032418 | 0.0079870728422 | 0.75 | BORCS8 BORCS5 BLOC1S1 | lysosome localization |
| GO:1990849 | 0.0079870728422 | 0.75 | BORCS8 BORCS5 BLOC1S1 | vacuolar localization |
| GO:0072384 | 0.0218982649712 | 0.75 | BORCS8 BORCS5 BLOC1S1 | organelle transport along microtubule |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| BORCS5 | BLOC1S1 | 0.999 | 0.254 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only |
| BORCS8 | BORCS5 | 0.999 | 0.57 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| BORCS8 | BLOC1S1 | 0.998 | 0.312 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TEX35 | BLOC1S1 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| TEX35 | BORCS5 | 0.983 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes