hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00085.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCNIP4 | Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Calsenilin-like protein) (Potassium channel-interacting protein 4) | 5 | UniProt NCBI |
| KCNIP2 | Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Cardiac voltage-gated potassium channel modulatory subunit) (Potassium channel-interacting protein 2) | 5 | UniProt NCBI |
| KCNIP3 | Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3) | 5 | UniProt NCBI |
| KCNIP1 | Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5576894 | 4.80157500167e-13 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | Phase 1 - inactivation of fast Na+ channels |
| REAC:R-HSA-5576891 | 1.94443140795e-07 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | Cardiac conduction |
| GO:0015459 | 1.07671286089e-06 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | potassium channel regulator activity |
| REAC:R-HSA-397014 | 1.94562459934e-06 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | Muscle contraction |
| GO:1901379 | 7.70499617526e-06 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | regulation of potassium ion transmembrane transport |
| GO:0008076 | 8.32139586928e-06 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | voltage-gated potassium channel complex |
| GO:0043266 | 1.11636599583e-05 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | regulation of potassium ion transport |
| GO:0034705 | 1.37313780553e-05 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | potassium channel complex |
| GO:0099106 | 8.74095077072e-05 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | ion channel regulator activity |
| GO:0141108 | 0.000107432498963 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | transporter regulator activity |
| GO:0016247 | 0.000107432498963 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | channel regulator activity |
| GO:0071805 | 0.000238882641259 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | potassium ion transmembrane transport |
| GO:0034703 | 0.000298882018117 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | cation channel complex |
| GO:0006813 | 0.000317929863268 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | potassium ion transport |
| GO:0034702 | 0.000822442198332 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | monoatomic ion channel complex |
| GO:1904062 | 0.00113809141431 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | regulation of monoatomic cation transmembrane transport |
| GO:0034765 | 0.00166799059677 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | regulation of monoatomic ion transmembrane transport |
| GO:0010959 | 0.00263891757684 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | regulation of metal ion transport |
| GO:1902495 | 0.00379124230895 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | transmembrane transporter complex |
| GO:0043269 | 0.0047455440478 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | regulation of monoatomic ion transport |
| GO:1990351 | 0.0052054047953 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | transporter complex |
| GO:0034762 | 0.00613433997379 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | regulation of transmembrane transport |
| GO:0005509 | 0.00728390316897 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | calcium ion binding |
| CORUM:6650 | 0.0249718442456 | 0.25 | KCNIP4 | KCND3-KCNIP4 complex |
| GO:0098797 | 0.0296421612139 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | plasma membrane protein complex |
| GO:0098662 | 0.0299356479586 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | inorganic cation transmembrane transport |
| GO:0098655 | 0.0311314419202 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | monoatomic cation transmembrane transport |
| GO:0098660 | 0.0416553027564 | 1.0 | KCNIP1 KCNIP4 KCNIP3 KCNIP2 | inorganic ion transmembrane transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| KCNIP2 | KCNIP1 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| KCNIP4 | KCNIP2 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| KCNIP4 | KCNIP1 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| KCNIP4 | KCNIP3 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| KCNIP3 | KCNIP1 | 0.543 | bioplex_WMM bioplex3_WMM WMM_only | |
| KCNIP2 | KCNIP3 | 0.502 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| KCNIP4 | huMAP3_00085.1 huMAP3_00657.1 huMAP3_01401.1 huMAP3_06786.1 huMAP3_08455.1 |
| KCNIP2 | huMAP3_00085.1 huMAP3_00657.1 huMAP3_08455.1 |
| KCNIP3 | huMAP3_00085.1 huMAP3_01401.1 huMAP3_06786.1 huMAP3_08455.1 |
| KCNIP1 | huMAP3_00085.1 huMAP3_00657.1 huMAP3_03591.1 huMAP3_06786.1 huMAP3_08455.1 huMAP3_11462.1 |