hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00106.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LPIN2 | Phosphatidate phosphatase LPIN2 (EC 3.1.3.4) (Lipin-2) | 5 | UniProt NCBI |
| LPIN3 | Phosphatidate phosphatase LPIN3 (EC 3.1.3.4) (Lipin-3) (Lipin-3-like) | 5 | UniProt NCBI |
| CAMKK1 | Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5275 | 0.000153947718176 | 0.666666666667 | LPIN3 LPIN2 | Ether lipid biosynthesis |
| WP:WP5101 | 0.000173183276299 | 0.666666666667 | LPIN3 LPIN2 | Congenital generalized lipodystrophy |
| REAC:R-HSA-1483213 | 0.000374861161166 | 0.666666666667 | LPIN3 LPIN2 | Synthesis of PE |
| REAC:R-HSA-75109 | 0.000449812862905 | 0.666666666667 | LPIN3 LPIN2 | Triglyceride biosynthesis |
| REAC:R-HSA-4419969 | 0.000531572756485 | 0.666666666667 | LPIN3 LPIN2 | Depolymerization of the Nuclear Lamina |
| KEGG:00561 | 0.00104947736992 | 0.666666666667 | LPIN3 LPIN2 | Glycerolipid metabolism |
| REAC:R-HSA-1483191 | 0.00172341693863 | 0.666666666667 | LPIN3 LPIN2 | Synthesis of PC |
| KEGG:00564 | 0.00234368320776 | 0.666666666667 | LPIN3 LPIN2 | Glycerophospholipid metabolism |
| REAC:R-HSA-8979227 | 0.0033773260227 | 0.666666666667 | LPIN3 LPIN2 | Triglyceride metabolism |
| KEGG:04936 | 0.00578906402762 | 0.666666666667 | LPIN3 LPIN2 | Alcoholic liver disease |
| WP:WP236 | 0.0063930178049 | 0.666666666667 | LPIN3 LPIN2 | Adipogenesis |
| REAC:R-HSA-2980766 | 0.00735562020533 | 0.666666666667 | LPIN3 LPIN2 | Nuclear Envelope Breakdown |
| KEGG:04150 | 0.00824863650471 | 0.666666666667 | LPIN3 LPIN2 | mTOR signaling pathway |
| REAC:R-HSA-1483206 | 0.037053837229 | 0.666666666667 | LPIN3 LPIN2 | Glycerophospholipid biosynthesis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| LPIN2 | LPIN3 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| LPIN3 | CAMKK1 | 0.968 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| LPIN2 | CAMKK1 | 0.303 | 0.094 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes