hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00112.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC22A15 | Solute carrier family 22 member 15 (Fly-like putative transporter 1) (Flipt 1) | 5 | UniProt NCBI |
| VAPA | Vesicle-associated membrane protein-associated protein A (VAMP-A) (VAMP-associated protein A) (VAP-A) (33 kDa VAMP-associated protein) (VAP-33) | 5 | UniProt NCBI |
| PITPNM1 | Membrane-associated phosphatidylinositol transfer protein 1 (Drosophila retinal degeneration B homolog) (Phosphatidylinositol transfer protein, membrane-associated 1) (PITPnm 1) (Pyk2 N-terminal domain-interacting receptor 2) (NIR-2) | 5 | UniProt NCBI |
| OSBP | Oxysterol-binding protein 1 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1660661 | 0.00573491177379 | 0.5 | VAPA OSBP | Sphingolipid de novo biosynthesis |
| GO:0015914 | 0.0100599149475 | 0.75 | VAPA PITPNM1 OSBP | phospholipid transport |
| REAC:R-HSA-428157 | 0.0267695204965 | 0.5 | VAPA OSBP | Sphingolipid metabolism |
| GO:0006686 | 0.0280843539964 | 0.5 | VAPA OSBP | sphingomyelin biosynthetic process |
| GO:0015748 | 0.0364824972322 | 0.75 | VAPA PITPNM1 OSBP | organophosphate ester transport |
| CORUM:6538 | 0.049938562206 | 0.25 | VAPA | SPG33-VAPA complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| VAPA | OSBP | 0.992 | 0.126 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| VAPA | PITPNM1 | 0.983 | 0.11 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SLC22A15 | VAPA | 0.957 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SLC22A15 | PITPNM1 | 0.902 | bioplex3_WMM WMM_only | |
| PITPNM1 | OSBP | 0.731 | 0.102 | bioplex_WMM bioplex3_WMM WMM_only |
| SLC22A15 | OSBP | 0.323 | bioplex3_WMM WMM_only |
Related Complexes