hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00113.1
Complex Portal: CPX-13463
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PDE8B | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (HsPDE8B) (EC 3.1.4.53) (Cell proliferation-inducing gene 22 protein) | 5 | UniProt NCBI |
| PDE8A | High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A (EC 3.1.4.53) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-418555 | 0.00715287669441 | 1.0 | PDE8B PDE8A | G alpha (s) signalling events |
| GO:0004115 | 0.0309012475255 | 1.0 | PDE8B PDE8A | 3',5'-cyclic-AMP phosphodiesterase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PDE8B | PDE8A | 0.979 | 0.13 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PDE8B | huMAP3_00113.1 huMAP3_11623.1 huMAP3_14850.1 |
| PDE8A | huMAP3_00113.1 huMAP3_08140.1 huMAP3_09214.1 huMAP3_11623.1 huMAP3_14850.1 |