hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00125.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
POMC | Pro-opiomelanocortin (POMC) (Corticotropin-lipotropin) [Cleaved into: NPP; Melanotropin gamma (Gamma-MSH); Potential peptide; Corticotropin (Adrenocorticotropic hormone) (ACTH); Melanocyte-stimulating hormone alpha (Alpha-MSH) (Melanotropin alpha); Corticotropin-like intermediary peptide (CLIP); Lipotropin beta (Beta-LPH); Lipotropin gamma (Gamma-LPH); Melanocyte-stimulating hormone beta (Beta-MSH) (Melanotropin beta); Beta-endorphin; Met-enkephalin] | 5 | UniProt   NCBI |
E2F4 | Transcription factor E2F4 (E2F-4) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-5579031 | 0.0249718442457 | 0.5 | POMC | Defective ACTH causes obesity and POMCD |
  CORUM:5099 | 0.0499419797295 | 0.5 | E2F4 | RB1(hypophosphorylated)-E2F4 complex |
  CORUM:5159 | 0.0499419797295 | 0.5 | E2F4 | E2F4-p107-cyclinE complex |
  CORUM:5160 | 0.0499419797295 | 0.5 | E2F4 | E2F4-p130 complex |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 POMC |  E2F4 | 0.95 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
Related Complexes