hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00132.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IL4R | Interleukin-4 receptor subunit alpha (IL-4 receptor subunit alpha) (IL-4R subunit alpha) (IL-4R-alpha) (IL-4RA) (CD antigen CD124) [Cleaved into: Soluble interleukin-4 receptor subunit alpha (Soluble IL-4 receptor subunit alpha) (Soluble IL-4R-alpha) (sIL4Ralpha/prot) (IL-4-binding protein) (IL4-BP)] | 5 | UniProt NCBI |
| IL13 | Interleukin-13 (IL-13) | 5 | UniProt NCBI |
| IL13RA1 | Interleukin-13 receptor subunit alpha-1 (IL-13 receptor subunit alpha-1) (IL-13R subunit alpha-1) (IL-13R-alpha-1) (IL-13RA1) (Cancer/testis antigen 19) (CT19) (CD antigen CD213a1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04630 | 0.00138428094844 | 1.0 | IL13 IL13RA1 | JAK-STAT signaling pathway |
| WP:WP5083 | 0.00259851399646 | 1.0 | IL13 IL13RA1 | Neuroinflammation and glutamatergic signaling |
| KEGG:04060 | 0.0031385705215 | 1.0 | IL13 IL13RA1 | Cytokine-cytokine receptor interaction |
| REAC:R-HSA-6785807 | 0.00654113998715 | 1.0 | IL13 IL13RA1 | Interleukin-4 and Interleukin-13 signaling |
| KEGG:05200 | 0.0161326036311 | 1.0 | IL13 IL13RA1 | Pathways in cancer |
| KEGG:05310 | 0.0403663802771 | 0.5 | IL13 | Asthma |
| CORUM:6685 | 0.0499419797295 | 0.5 | IL13RA1 | IL13RA1-TRAF3IP1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| IL13 | IL13RA1 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| IL4R | IL13 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| IL4R | IL13RA1 | 0.904 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| IL4R | huMAP3_00132.1 huMAP3_02936.1 |
| IL13 | huMAP3_00132.1 huMAP3_02936.1 huMAP3_07355.1 |
| IL13RA1 | huMAP3_00132.1 huMAP3_00422.1 huMAP3_00986.1 huMAP3_02936.1 |