hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00134.1
Complex Portal: CPX-19149
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PI4KA | Phosphatidylinositol 4-kinase alpha (PI4-kinase alpha) (PI4K-alpha) (PtdIns-4-kinase alpha) (EC 2.7.1.67) (Phosphatidylinositol 4-Kinase III alpha) | 5 | UniProt NCBI |
| HYCC1 | Hyccin (Down-regulated by CTNNB1 protein A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6890 | 1.02525705128e-05 | 1.0 | PI4KA HYCC1 | Phosphatidylinositol 4-kinase complex |
| HP:0030187 | 0.00148662272435 | 1.0 | PI4KA HYCC1 | Titubation |
| HP:0003429 | 0.0102628230833 | 1.0 | PI4KA HYCC1 | CNS hypomyelination |
| HP:0002080 | 0.0133830220427 | 1.0 | PI4KA HYCC1 | Intention tremor |
| HP:0002415 | 0.0149379952371 | 1.0 | PI4KA HYCC1 | Leukodystrophy |
| HP:0030186 | 0.0149379952371 | 1.0 | PI4KA HYCC1 | Kinetic tremor |
| HP:0002345 | 0.0496737041344 | 1.0 | PI4KA HYCC1 | Action tremor |
| HP:0012454 | 0.0499436884913 | 0.5 | PI4KA | Unilateral wrist flexion contracture |
| HP:0032965 | 0.0499436884913 | 0.5 | PI4KA | Interstitial emphysema |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PI4KA | HYCC1 | 0.992 | 0.19 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| PI4KA | huMAP3_00134.1 huMAP3_03063.1 huMAP3_08176.1 |
| HYCC1 | huMAP3_00134.1 huMAP3_03063.1 huMAP3_03300.1 huMAP3_08176.1 huMAP3_08206.1 huMAP3_09109.1 |