hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00149.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NDUFA10 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Complex I-42kD) (CI-42kD) (NADH-ubiquinone oxidoreductase 42 kDa subunit) | 5 | UniProt NCBI |
| NDUFB4 | NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 (Complex I-B15) (CI-B15) (NADH-ubiquinone oxidoreductase B15 subunit) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4324 | 0.000632070972113 | 1.0 | NDUFA10 NDUFB4 | Mitochondrial complex I assembly model OXPHOS system |
| WP:WP623 | 0.000728264938239 | 1.0 | NDUFA10 NDUFB4 | Oxidative phosphorylation |
| KEGG:04723 | 0.0011414018249 | 1.0 | NDUFA10 NDUFB4 | Retrograde endocannabinoid signaling |
| KEGG:00190 | 0.00119992691491 | 1.0 | NDUFA10 NDUFB4 | Oxidative phosphorylation |
| CORUM:178 | 0.00154301186217 | 1.0 | NDUFA10 NDUFB4 | Respiratory chain complex I (holoenzyme), mitochondrial |
| KEGG:04932 | 0.00155920593969 | 1.0 | NDUFA10 NDUFB4 | Non-alcoholic fatty liver disease |
| WP:WP111 | 0.00202305274778 | 1.0 | NDUFA10 NDUFB4 | Electron transport chain OXPHOS system in mitochondria |
| KEGG:05415 | 0.00267768543767 | 1.0 | NDUFA10 NDUFB4 | Diabetic cardiomyopathy |
| REAC:R-HSA-6799198 | 0.0027271837564 | 1.0 | NDUFA10 NDUFB4 | Complex I biogenesis |
| KEGG:05208 | 0.0033003273675 | 1.0 | NDUFA10 NDUFB4 | Chemical carcinogenesis - reactive oxygen species |
| KEGG:04714 | 0.00339933231144 | 1.0 | NDUFA10 NDUFB4 | Thermogenesis |
| WP:WP4396 | 0.00396523446209 | 1.0 | NDUFA10 NDUFB4 | Nonalcoholic fatty liver disease |
| KEGG:05012 | 0.00458495309323 | 1.0 | NDUFA10 NDUFB4 | Parkinson disease |
| KEGG:05020 | 0.00485920816781 | 1.0 | NDUFA10 NDUFB4 | Prion disease |
| KEGG:05016 | 0.00594761227231 | 1.0 | NDUFA10 NDUFB4 | Huntington disease |
| REAC:R-HSA-611105 | 0.00828920325958 | 1.0 | NDUFA10 NDUFB4 | Respiratory electron transport |
| KEGG:05014 | 0.00850662183301 | 1.0 | NDUFA10 NDUFB4 | Amyotrophic lateral sclerosis |
| KEGG:05010 | 0.0093688914925 | 1.0 | NDUFA10 NDUFB4 | Alzheimer disease |
| REAC:R-HSA-163200 | 0.0124056103205 | 1.0 | NDUFA10 NDUFB4 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| KEGG:05022 | 0.0138982457502 | 1.0 | NDUFA10 NDUFB4 | Pathways of neurodegeneration - multiple diseases |
| REAC:R-HSA-1428517 | 0.0242575818332 | 1.0 | NDUFA10 NDUFB4 | The citric acid (TCA) cycle and respiratory electron transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NDUFA10 | NDUFB4 | 0.997 | 0.922 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM fraction |
Related Complexes