hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00157.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RFLNB | Refilin-B (Regulator of filamin protein B) (RefilinB) | 3 | UniProt NCBI |
| FBLIM1 | Filamin-binding LIM protein 1 (FBLP-1) (Migfilin) (Mitogen-inducible 2-interacting protein) (MIG2-interacting protein) | 5 | UniProt NCBI |
| SHB | SH2 domain-containing adapter protein B | 5 | UniProt NCBI |
| CBL | E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5713 | 0.0249718442456 | 0.25 | CBL | SH3P2/OSTF1-CBL-SRC complex |
| CORUM:2534 | 0.049938562206 | 0.25 | CBL | Cbl-SLP-76-Grb2 complex, Fc receptor gamma-R1 stimulated |
| CORUM:2535 | 0.049938562206 | 0.25 | CBL | SLP-76-Cbl-Grb2-Shc complex, Fc receptor gamma-R1 stimulated |
| CORUM:3175 | 0.049938562206 | 0.25 | CBL | CIN85-CBL complex |
| CORUM:5709 | 0.049938562206 | 0.25 | CBL | ArgBP2a-CBL-PTK2B complex |
| CORUM:5720 | 0.049938562206 | 0.25 | CBL | CIN85-CBL complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| FBLIM1 | SHB | 0.998 | 0.078 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| RFLNB | FBLIM1 | 0.994 | 0.088 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| FBLIM1 | CBL | 0.981 | 0.05 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only |
| SHB | CBL | 0.953 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only |
| RFLNB | SHB | 0.757 | 0.056 | bioplex3_WMM WMM_only |
| RFLNB | CBL | 0.568 | 0.142 | bioplex3_WMM youn_WMM WMM_only |
Related Complexes