hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00158.1
Complex Portal: CPX-15339
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| GRK4 | G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1) | 5 | UniProt NCBI |
| GRK6 | G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05032 | 0.00037033376401 | 1.0 | GRK4 GRK6 | Morphine addiction |
| KEGG:04062 | 0.00155920593969 | 1.0 | GRK4 GRK6 | Chemokine signaling pathway |
| WP:WP536 | 0.00264575970549 | 1.0 | GRK4 GRK6 | Calcium regulation in cardiac cells |
| WP:WP3929 | 0.00309012475255 | 1.0 | GRK4 GRK6 | Chemokine signaling pathway |
| WP:WP289 | 0.00362429921046 | 1.0 | GRK4 GRK6 | Myometrial relaxation and contraction pathways |
| KEGG:04144 | 0.00431866393369 | 1.0 | GRK4 GRK6 | Endocytosis |
| GO:0004703 | 0.00468200720083 | 1.0 | GRK4 GRK6 | G protein-coupled receptor kinase activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GRK4 | GRK6 | 0.992 | 0.24 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| GRK4 | huMAP3_00158.1 huMAP3_09140.1 huMAP3_12831.1 huMAP3_14300.1 |
| GRK6 | huMAP3_00158.1 huMAP3_06673.1 huMAP3_09140.1 huMAP3_12831.1 |