hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00166.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CDC14A | Dual specificity protein phosphatase CDC14A (EC 3.1.3.16) (EC 3.1.3.48) (CDC14 cell division cycle 14 homolog A) | 5 | UniProt NCBI |
| SACS | Sacsin (DnaJ homolog subfamily C member 29) (DNAJC29) | 5 | UniProt NCBI |
| SPSB4 | SPRY domain-containing SOCS box protein 4 (SSB-4) | 5 | UniProt NCBI |
| EPHB1 | Ephrin type-B receptor 1 (EC 2.7.10.1) (ELK) (EPH tyrosine kinase 2) (EPH-like kinase 6) (EK6) (hEK6) (Neuronally-expressed EPH-related tyrosine kinase) (NET) (Tyrosine-protein kinase receptor EPH-2) | 5 | UniProt NCBI |
| SPSB1 | SPRY domain-containing SOCS box protein 1 (SSB-1) | 5 | UniProt NCBI |
| ACSM3 | Acyl-coenzyme A synthetase ACSM3, mitochondrial (EC 6.2.1.2) (Acyl-CoA synthetase medium-chain family member 3) (Butyrate--CoA ligase 3) (Butyryl-coenzyme A synthetase 3) (Middle-chain acyl-CoA synthetase 3) (Propionate--CoA ligase) (EC 6.2.1.17) (Protein SA homolog) | 5 | UniProt NCBI |
| SIK2 | Serine/threonine-protein kinase SIK2 (EC 2.7.11.1) (Qin-induced kinase) (Salt-inducible kinase 2) (SIK-2) (Serine/threonine-protein kinase SNF1-like kinase 2) | 5 | UniProt NCBI |
| SH2B1 | SH2B adapter protein 1 (Pro-rich, PH and SH2 domain-containing signaling mediator) (PSM) (SH2 domain-containing protein 1B) | 5 | UniProt NCBI |
| TTC1 | Tetratricopeptide repeat protein 1 (TPR repeat protein 1) | 4 | UniProt NCBI |
| PARG | Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SPSB4 | ACSM3 | 0.998 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SPSB4 | SIK2 | 0.997 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SPSB1 | TTC1 | 0.994 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SACS | SPSB4 | 0.993 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SPSB4 | SPSB1 | 0.987 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SPSB4 | EPHB1 | 0.986 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CDC14A | SPSB4 | 0.985 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SPSB4 | TTC1 | 0.983 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| SPSB4 | SH2B1 | 0.975 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| SPSB4 | PARG | 0.973 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ACSM3 | TTC1 | 0.825 | 0.066 | bioplex3_WMM WMM_only |
| SACS | SIK2 | 0.78 | 0.05 | bioplex3_WMM WMM_only |
| SACS | ACSM3 | 0.757 | 0.028 | bioplex3_WMM WMM_only |
| ACSM3 | SIK2 | 0.72 | 0.088 | bioplex3_WMM WMM_only |
| SIK2 | TTC1 | 0.49 | 0.094 | bioplex3_WMM youn_WMM WMM_only |
| SACS | PARG | 0.415 | 0.034 | bioplex3_WMM WMM_only |
| EPHB1 | SPSB1 | 0.415 | bioplex3_WMM WMM_only | |
| EPHB1 | SH2B1 | 0.415 | bioplex3_WMM WMM_only | |
| EPHB1 | PARG | 0.415 | bioplex3_WMM WMM_only | |
| CDC14A | SH2B1 | 0.415 | bioplex3_WMM WMM_only | |
| SPSB1 | PARG | 0.415 | bioplex3_WMM WMM_only | |
| SPSB1 | ACSM3 | 0.415 | bioplex3_WMM WMM_only | |
| SPSB1 | SH2B1 | 0.415 | bioplex3_WMM WMM_only | |
| ACSM3 | PARG | 0.415 | 0.072 | bioplex3_WMM WMM_only |
| CDC14A | EPHB1 | 0.415 | bioplex3_WMM WMM_only | |
| CDC14A | SPSB1 | 0.415 | bioplex3_WMM WMM_only | |
| CDC14A | PARG | 0.415 | bioplex3_WMM WMM_only | |
| SH2B1 | PARG | 0.415 | 0.09 | bioplex3_WMM WMM_only |
| SACS | TTC1 | 0.319 | 0.006 | bioplex3_WMM youn_WMM WMM_only |
| SIK2 | PARG | 0.274 | 0.064 | bioplex3_WMM WMM_only |
| CDC14A | ACSM3 | 0.274 | bioplex3_WMM WMM_only | |
| EPHB1 | ACSM3 | 0.274 | bioplex3_WMM WMM_only | |
| ACSM3 | SH2B1 | 0.274 | 0.054 | bioplex3_WMM WMM_only |
| SACS | SPSB1 | 0.25 | bioplex3_WMM WMM_only | |
| SPSB1 | SIK2 | 0.113 | bioplex3_WMM WMM_only | |
| SACS | EPHB1 | 0.113 | bioplex3_WMM WMM_only | |
| CDC14A | SACS | 0.113 | bioplex3_WMM WMM_only | |
| SACS | SH2B1 | 0.113 | 0.04 | bioplex3_WMM WMM_only |
| TTC1 | PARG | 0.102 | 0.056 | bioplex3_WMM WMM_only |
| EPHB1 | SIK2 | 0.078 | bioplex3_WMM WMM_only | |
| CDC14A | SIK2 | 0.078 | bioplex3_WMM WMM_only | |
| SIK2 | SH2B1 | 0.078 | 0.116 | bioplex3_WMM WMM_only |
| CDC14A | TTC1 | 0.071 | bioplex3_WMM WMM_only | |
| EPHB1 | TTC1 | 0.071 | bioplex3_WMM WMM_only | |
| SH2B1 | TTC1 | 0.071 | 0.058 | bioplex3_WMM WMM_only |
Related Complexes