hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00173.1
Complex Portal: CPX-11769
Confidence: Extremely High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| WDR37 | WD repeat-containing protein 37 | 5 | UniProt   NCBI |
| LEAP2 | Liver-expressed antimicrobial peptide 2 (LEAP-2) | 3 | UniProt   NCBI |
| PACS1 | Phosphofurin acidic cluster sorting protein 1 (PACS-1) | 5 | UniProt   NCBI |
| PACS2 | Phosphofurin acidic cluster sorting protein 2 (PACS-2) (PACS1-like protein) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   HP:0002714 | 0.00235645810497 | 0.75 | WDR37 PACS1 PACS2 | Downturned corners of mouth |
|   HP:0011338 | 0.011350921992 | 0.75 | WDR37 PACS1 PACS2 | Abnormality of mouth shape |
|   CORUM:1927 | 0.049938562206 | 0.25 | PACS1 | PKD2-PACS1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  WDR37 |  PACS1 | 0.999 | 0.278           |
structurally_consistent (dimer)        
|
bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     boldt_WMM     |
|  WDR37 |  PACS2 | 0.997 | 0.116           |
structurally_consistent (dimer)        
|
bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     |
|  WDR37 |  LEAP2 | 0.965 |            |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
|  PACS1 |  PACS2 | 0.964 | 0.094           |
mutually_exclusive (Q9Y2I8)        
|
bioplex_WMM     bioplex3_WMM     youn_WMM     WMM_only     |
|  LEAP2 |  PACS1 | 0.949 |            |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
|  LEAP2 |  PACS2 | 0.931 |            |          | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
Related Complexes