hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00206.1
Complex Portal: CPX-16009
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RBBP4 | Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48) | 5 | UniProt NCBI |
| SMARCA1 | Probable global transcription activator SNF2L1 (EC 3.6.4.-) (ATP-dependent helicase SMARCA1) (Nucleosome-remodeling factor subunit SNF2L) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1) | 5 | UniProt NCBI |
| BPTF | Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen) | 5 | UniProt NCBI |
| PWWP2B | PWWP domain-containing protein 2B | 5 | UniProt NCBI |
| ZNF512B | Zinc finger protein 512B | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:100 | 1.53774525569e-05 | 0.5 | BPTF RBBP4 | hNURF complex |
| CORUM:919 | 1.53774525569e-05 | 0.5 | BPTF RBBP4 | hNURF complex |
| KEGG:03082 | 0.0133093129958 | 0.5 | BPTF RBBP4 | ATP-dependent chromatin remodeling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RBBP4 | PWWP2B | 0.996 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| RBBP4 | BPTF | 0.995 | 0.214 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only | |
| RBBP4 | ZNF512B | 0.979 | 0.294 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| RBBP4 | SMARCA1 | 0.972 | 0.216 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction | |
| SMARCA1 | BPTF | 0.933 | 0.214 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| SMARCA1 | PWWP2B | 0.595 | bioplex3_WMM WMM_only | ||
| BPTF | PWWP2B | 0.555 | bioplex3_WMM youn_WMM WMM_only | ||
| BPTF | ZNF512B | 0.405 | 0.292 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| SMARCA1 | ZNF512B | 0.361 | 0.172 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| PWWP2B | ZNF512B | 0.241 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes