hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00207.1
Complex Portal: CPX-17292
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| WBP2 | WW domain-binding protein 2 (WBP-2) | 5 | UniProt NCBI |
| VASP | Vasodilator-stimulated phosphoprotein (VASP) | 5 | UniProt NCBI |
| ENAH | Protein enabled homolog | 5 | UniProt NCBI |
| ZYX | Zyxin (Zyxin-2) | 5 | UniProt NCBI |
| TACC3 | Transforming acidic coiled-coil-containing protein 3 (ERIC-1) | 5 | UniProt NCBI |
| SLAIN2 | SLAIN motif-containing protein 2 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-202433 | 0.0070977267476 | 0.333333333333 | VASP ENAH | Generation of second messenger molecules |
| WP:WP185 | 0.0346027913493 | 0.333333333333 | ZYX VASP | Integrin mediated cell adhesion |
| CORUM:6731 | 0.0499436884912 | 0.166666666667 | VASP | VASP-CXCR2 complex, CXCL8 stimulated |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| VASP | ENAH | 1.0 | 0.052 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt Malo bioplex3_HCT116 gupta_WMM fraction boldt_WMM | |
| ENAH | ZYX | 0.996 | 0.072 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM | |
| TACC3 | ENAH | 0.989 | 0.08 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM | |
| TACC3 | VASP | 0.989 | 0.08 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () gupta_WMM | |
| TACC3 | SLAIN2 | 0.974 | 0.074 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM fraction | |
| VASP | ZYX | 0.97 | 0.424 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM fraction | |
| WBP2 | VASP | 0.957 | 0.034 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SLAIN2 | VASP | 0.95 | 0.066 | hein_WMM bioplex3_WMM WMM_only | |
| SLAIN2 | ENAH | 0.433 | 0.044 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| WBP2 | ENAH | 0.204 | 0.036 | bioplex_WMM bioplex3_WMM WMM_only | |
| WBP2 | ZYX | 0.112 | 0.054 | bioplex_WMM bioplex3_WMM WMM_only | |
| TACC3 | ZYX | 0.059 | 0.122 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| TACC3 | WBP2 | 0.009 | 0.0545714285714 | bioplex_WMM WMM_only | |
| SLAIN2 | ZYX | 0.003 | 0.116 | youn_WMM gupta_WMM fraction |
Related Complexes