hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00223.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CAV2 | Caveolin-2 | 5 | UniProt NCBI |
| CAV1 | Caveolin-1 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05100 | 0.000463323629249 | 1.0 | CAV2 CAV1 | Bacterial invasion of epithelial cells |
| KEGG:05418 | 0.0011031979467 | 1.0 | CAV2 CAV1 | Fluid shear stress and atherosclerosis |
| WP:WP185 | 0.00148377064565 | 1.0 | CAV2 CAV1 | Integrin mediated cell adhesion |
| KEGG:04510 | 0.00241871191437 | 1.0 | CAV2 CAV1 | Focal adhesion |
| KEGG:05205 | 0.00267768543767 | 1.0 | CAV2 CAV1 | Proteoglycans in cancer |
| GO:0070836 | 0.0028092043205 | 1.0 | CAV2 CAV1 | caveola assembly |
| WP:WP4217 | 0.00283899891178 | 1.0 | CAV2 CAV1 | Ebola virus infection in host |
| REAC:R-HSA-9009391 | 0.00323126847328 | 1.0 | CAV2 CAV1 | Extra-nuclear estrogen signaling |
| HPA:0271113 | 0.00367399151171 | 1.0 | CAV2 CAV1 | kidney; bowman's capsule[High] |
| KEGG:04144 | 0.00431866393369 | 1.0 | CAV2 CAV1 | Endocytosis |
| WP:WP437 | 0.00438235873998 | 1.0 | CAV2 CAV1 | EGF EGFR signaling pathway |
| GO:0044854 | 0.00468200720083 | 1.0 | CAV2 CAV1 | plasma membrane raft assembly |
| KEGG:05020 | 0.00485920816781 | 1.0 | CAV2 CAV1 | Prion disease |
| WP:WP306 | 0.00633262755764 | 1.0 | CAV2 CAV1 | Focal adhesion |
| HPA:0461393 | 0.0101319117266 | 1.0 | CAV2 CAV1 | skin 1; cells in basal layer[High] |
| HPA:0271112 | 0.010805326387 | 1.0 | CAV2 CAV1 | kidney; bowman's capsule[>=Medium] |
| HPA:0380203 | 0.0154367823533 | 1.0 | CAV2 CAV1 | placenta; endothelial cells[High] |
| GO:0019065 | 0.016855225923 | 1.0 | CAV2 CAV1 | receptor-mediated endocytosis of virus by host cell |
| GO:0001765 | 0.016855225923 | 1.0 | CAV2 CAV1 | membrane raft assembly |
| GO:0044857 | 0.016855225923 | 1.0 | CAV2 CAV1 | plasma membrane raft organization |
| HPA:0271111 | 0.0185811895029 | 1.0 | CAV2 CAV1 | kidney; bowman's capsule[>=Low] |
| HPA:0300203 | 0.0221799559632 | 1.0 | CAV2 CAV1 | lung; endothelial cells[High] |
| HPA:0471393 | 0.0240136418168 | 1.0 | CAV2 CAV1 | skin 2; cells in basal layer[High] |
| CORUM:5714 | 0.0249718442457 | 0.5 | CAV1 | NOS3-CAV1 complex |
| CORUM:2462 | 0.0249718442457 | 0.5 | CAV1 | Caveolin-1 homodimer complex |
| CORUM:550 | 0.0249718442457 | 0.5 | CAV1 | NOS3-CAV1-NOSTRIN complex |
| GO:0075509 | 0.0257510396046 | 1.0 | CAV2 CAV1 | endocytosis involved in viral entry into host cell |
| HPA:0460203 | 0.0268108101291 | 1.0 | CAV2 CAV1 | skin 1; endothelial cells[High] |
| HPA:0470203 | 0.0271712885755 | 1.0 | CAV2 CAV1 | skin 2; endothelial cells[High] |
| HPA:0380202 | 0.0280830161988 | 1.0 | CAV2 CAV1 | placenta; endothelial cells[>=Medium] |
| REAC:R-HSA-8939211 | 0.0290831250212 | 1.0 | CAV2 CAV1 | ESR-mediated signaling |
| HPA:0170253 | 0.0324707429985 | 1.0 | CAV2 CAV1 | endometrium 2; cells in endometrial stroma[High] |
| HPA:0340463 | 0.0376010915058 | 1.0 | CAV2 CAV1 | ovary; ovarian stroma cells[High] |
| HPA:0380201 | 0.0406383781822 | 1.0 | CAV2 CAV1 | placenta; endothelial cells[>=Low] |
| HPA:0100203 | 0.0426532059597 | 1.0 | CAV2 CAV1 | cerebral cortex; endothelial cells[High] |
| CORUM:557 | 0.0499419797295 | 0.5 | CAV1 | TRP1-G alpha-11-IP3R3-CAV1 signaling complex |
| CORUM:5862 | 0.0499419797295 | 0.5 | CAV1 | CAV1-VDAC1-ESR1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CAV2 | CAV1 | 0.97 | 0.826 | bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
Related Complexes