List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_00229.1

Confidence: Extremely High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
SMC3	Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Basement membrane-associated chondroitin proteoglycan) (Bamacan) (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP)	5	UniProt   NCBI
STAG1	Cohesin subunit SA-1 (SCC3 homolog 1) (Stromal antigen 1)	5	UniProt   NCBI
USP13	Ubiquitin carboxyl-terminal hydrolase 13 (EC 3.4.19.12) (Deubiquitinating enzyme 13) (Isopeptidase T-3) (ISOT-3) (Ubiquitin thioesterase 13) (Ubiquitin-specific-processing protease 13)	5	UniProt   NCBI
CDCA5	Sororin (Cell division cycle-associated protein 5) (p35)	5	UniProt   NCBI
SMC1A	Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8)	5	UniProt   NCBI
WAPL	Wings apart-like protein homolog (Friend of EBNA2 protein) (WAPL cohesin release factor)	5	UniProt   NCBI
RAD21	Double-strand-break repair protein rad21 homolog (hHR21) (Nuclear matrix protein 1) (NXP-1) (SCC1 homolog) [Cleaved into: 64-kDa C-terminal product (64-kDa carboxy-terminal product) (65-kDa carboxy-terminal product)]	5	UniProt   NCBI
REC8	Meiotic recombination protein REC8 homolog (Cohesin Rec8p)	5	UniProt   NCBI
SMC1B	Structural maintenance of chromosomes protein 1B (SMC protein 1B) (SMC-1-beta) (SMC-1B)	5	UniProt   NCBI
PDS5B	Sister chromatid cohesion protein PDS5 homolog B (Androgen-induced proliferation inhibitor) (Androgen-induced prostate proliferative shutoff-associated protein AS3)	5	UniProt   NCBI
STAG2	Cohesin subunit SA-2 (SCC3 homolog 2) (Stromal antigen 2)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-2468052	3.73175145415e-23	0.727272727273	SMC1A WAPL SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	Establishment of Sister Chromatid Cohesion
WP:WP5117	1.38024015487e-21	0.818181818182	SMC1A WAPL CDCA5 SMC1B SMC3 RAD21 REC8 STAG2 PDS5B	Cohesin complex Cornelia de Lange syndrome
GO:0007062	1.83135382759e-20	0.909090909091	SMC1A WAPL REC8 SMC1B SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	sister chromatid cohesion
REAC:R-HSA-2470946	3.63294298509e-19	0.636363636364	SMC1A PDS5B SMC3 RAD21 STAG1 STAG2 WAPL	Cohesin Loading onto Chromatin
GO:0008278	4.67662755482e-18	0.636363636364	SMC1A STAG2 SMC1B SMC3 RAD21 STAG1 REC8	cohesin complex
REAC:R-HSA-68884	5.19137434943e-18	0.636363636364	SMC1A PDS5B SMC3 RAD21 STAG1 STAG2 WAPL	Mitotic Telophase/Cytokinesis
KEGG:04110	2.90511846816e-15	0.818181818182	SMC1A WAPL SMC1B SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	Cell cycle
CORUM:5432	3.31362939534e-14	0.454545454545	PDS5B SMC1A RAD21 SMC3 CDCA5	Sororin-cohesin complex
CORUM:1856	3.31362939534e-14	0.454545454545	PDS5B SMC1A RAD21 SMC3 CDCA5	Sororin-cohesin complex
GO:0034085	1.4338190395e-13	0.545454545455	SMC1A STAG2 SMC3 RAD21 STAG1 WAPL	establishment of sister chromatid cohesion
GO:0007064	5.16763737141e-13	0.636363636364	SMC1A PDS5B SMC3 RAD21 STAG1 CDCA5 STAG2	mitotic sister chromatid cohesion
REAC:R-HSA-2500257	7.31122998418e-13	0.727272727273	SMC1A WAPL SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	Resolution of Sister Chromatid Cohesion
REAC:R-HSA-1221632	1.47042255243e-12	0.636363636364	SMC1A STAG2 SMC1B SMC3 RAD21 STAG1 REC8	Meiotic synapsis
REAC:R-HSA-69242	6.83561216978e-12	0.727272727273	SMC1A WAPL SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	S Phase
CORUM:163	1.15314319164e-11	0.363636363636	SMC1A SMC3 STAG2 RAD21	Cohesin-SA2 complex
CORUM:64	1.15314319164e-11	0.363636363636	SMC1A SMC3 STAG2 RAD21	Cohesin-SA2 complex
CORUM:63	1.15314319164e-11	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Cohesin-SA1 complex
CORUM:164	1.15314319164e-11	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Cohesin-SA1 complex
CORUM:165	1.15314319164e-11	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Cohesin-SA1 complex
CORUM:166	1.15314319164e-11	0.363636363636	SMC1A SMC3 STAG2 RAD21	Cohesin-SA2 complex
REAC:R-HSA-2467813	2.24309428923e-11	0.727272727273	SMC1A WAPL SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	Separation of Sister Chromatids
CORUM:282	2.40407696616e-11	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	SNF2h-cohesin-NuRD complex
GO:0030892	2.49516293469e-11	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	mitotic cohesin complex
WP:WP5402	2.8719806423e-11	0.545454545455	SMC1A PDS5B SMC3 RAD21 STAG1 WAPL	10q22q23 copy number variation
REAC:R-HSA-68877	3.59359944182e-11	0.727272727273	SMC1A WAPL SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	Mitotic Prometaphase
REAC:R-HSA-1500620	4.41162462948e-11	0.636363636364	SMC1A STAG2 SMC1B SMC3 RAD21 STAG1 REC8	Meiosis
REAC:R-HSA-1640170	7.40068737515e-11	0.909090909091	SMC1A WAPL REC8 SMC1B SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	Cell Cycle
GO:0034087	8.73008139488e-11	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	establishment of mitotic sister chromatid cohesion
REAC:R-HSA-68882	1.06529071462e-10	0.727272727273	SMC1A WAPL SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	Mitotic Anaphase
REAC:R-HSA-1474165	1.07021987996e-10	0.636363636364	SMC1A STAG2 SMC1B SMC3 RAD21 STAG1 REC8	Reproduction
REAC:R-HSA-2555396	1.10454163792e-10	0.727272727273	SMC1A WAPL SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	Mitotic Metaphase and Anaphase
GO:0051276	1.11702382493e-09	0.909090909091	SMC1A WAPL REC8 SMC1B SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	chromosome organization
GO:0000775	7.22944597127e-09	0.727272727273	SMC1A WAPL SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	chromosome, centromeric region
GO:0030893	8.68316823302e-09	0.363636363636	SMC1A SMC1B SMC3 RAD21	meiotic cohesin complex
REAC:R-HSA-68886	8.97439893997e-09	0.727272727273	SMC1A WAPL SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	M Phase
WP:WP179	1.02459353724e-08	0.545454545455	SMC1A STAG2 SMC1B SMC3 RAD21 STAG1	Cell cycle
WP:WP4240	1.80763865478e-08	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Regulation of sister chromatid separation at the metaphase anaphase transition
CORUM:6303	8.42140472852e-08	0.272727272727	SMC1A SMC3 RAD21	DDX11-RAD21-SMC1A-SMC3 complex
REAC:R-HSA-69278	1.03819500945e-07	0.727272727273	SMC1A WAPL SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	Cell Cycle, Mitotic
HP:0007665	1.60344243637e-07	0.363636363636	SMC1A SMC3 STAG2 RAD21	Curly eyelashes
REAC:R-HSA-3108214	2.74359583922e-07	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	SUMOylation of DNA damage response and repair proteins
GO:0000280	3.32582643289e-07	0.727272727273	SMC1A WAPL REC8 SMC3 RAD21 STAG1 CDCA5 STAG2	nuclear division
GO:0098687	3.68052158603e-07	0.727272727273	SMC1A WAPL SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	chromosomal region
GO:0051177	6.06890408176e-07	0.363636363636	SMC1A REC8 SMC3 RAD21	meiotic sister chromatid cohesion
GO:0048285	8.48409918808e-07	0.727272727273	SMC1A WAPL REC8 SMC3 RAD21 STAG1 CDCA5 STAG2	organelle fission
GO:0022402	9.09743905371e-07	0.909090909091	SMC1A WAPL REC8 SMC1B SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	cell cycle process
REAC:R-HSA-9018519	5.25507810867e-06	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Estrogen-dependent gene expression
WP:WP5118	5.4452678611e-06	0.272727272727	SMC1A SMC3 RAD21	SMC1 SMC3 role in DNA damage Cornelia de Lange Syndrome
HPA:0381213	6.29210082714e-06	0.545454545455	SMC1A PDS5B WAPL RAD21 CDCA5 STAG2	placenta; syncytiotrophoblasts - cell body[High]
GO:0007049	1.07881852046e-05	0.909090909091	SMC1A WAPL REC8 SMC1B SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	cell cycle
REAC:R-HSA-3108232	1.5742095756e-05	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	SUMO E3 ligases SUMOylate target proteins
GO:0034089	1.58598067776e-05	0.272727272727	SMC1A SMC3 RAD21	establishment of meiotic sister chromatid cohesion
REAC:R-HSA-2990846	1.84003235283e-05	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	SUMOylation
HPA:0381212	3.0261550602e-05	0.545454545455	SMC1A PDS5B WAPL RAD21 CDCA5 STAG2	placenta; syncytiotrophoblasts - cell body[>=Medium]
GO:0005694	3.107722397e-05	0.909090909091	SMC1A WAPL REC8 SMC1B SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	chromosome
CORUM:5241	3.41979277617e-05	0.181818181818	SMC1A SMC3	SMC1-SMC3 complex
REAC:R-HSA-8939211	3.46475843482e-05	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	ESR-mediated signaling
GO:0000070	3.59299225932e-05	0.545454545455	SMC1A WAPL SMC3 STAG1 CDCA5 STAG2	mitotic sister chromatid segregation
HP:0000413	3.63842139245e-05	0.363636363636	SMC1A SMC3 STAG2 RAD21	Atresia of the external auditory canal
KEGG:04114	3.9165862579e-05	0.363636363636	SMC1A SMC1B SMC3 REC8	Oocyte meiosis
HP:0010880	3.94655822821e-05	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Increased nuchal translucency
HPA:0380203	5.2609185392e-05	0.454545454545	SMC1A PDS5B WAPL STAG2 RAD21	placenta; endothelial cells[High]
HP:0010300	6.43756062764e-05	0.272727272727	SMC1A SMC3 RAD21	Abnormally low-pitched voice
HPA:0381211	6.44467398346e-05	0.545454545455	SMC1A PDS5B WAPL RAD21 CDCA5 STAG2	placenta; syncytiotrophoblasts - cell body[>=Low]
GO:0016363	6.54461776022e-05	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	nuclear matrix
HP:0000667	0.000106424889478	0.272727272727	SMC1A SMC3 RAD21	Phthisis bulbi
HP:0000965	0.000113166012757	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Cutis marmorata
GO:0000819	0.000132959909624	0.545454545455	SMC1A WAPL SMC3 STAG1 CDCA5 STAG2	sister chromatid segregation
HP:0002580	0.000132976469997	0.272727272727	SMC1A SMC3 RAD21	Volvulus
REAC:R-HSA-9006931	0.000145869491754	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Signaling by Nuclear Receptors
HP:0000372	0.000211591940141	0.363636363636	SMC1A SMC3 STAG2 RAD21	Abnormality of the auditory canal
GO:0034399	0.000221482194709	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	nuclear periphery
HPA:0380202	0.00023048431569	0.454545454545	SMC1A PDS5B WAPL STAG2 RAD21	placenta; endothelial cells[>=Medium]
HP:0000776	0.000272949798716	0.363636363636	SMC1A SMC3 STAG2 RAD21	Congenital diaphragmatic hernia
GO:0140014	0.000277111437904	0.545454545455	SMC1A WAPL SMC3 STAG1 CDCA5 STAG2	mitotic nuclear division
HP:0010034	0.000282731012242	0.272727272727	SMC1A SMC3 RAD21	Short 1st metacarpal
GO:0097431	0.00035138481807	0.363636363636	STAG1 SMC3 STAG2 SMC1A	mitotic spindle pole
GO:0098813	0.000417607436328	0.545454545455	SMC1A WAPL SMC3 STAG1 CDCA5 STAG2	nuclear chromosome segregation
HP:0000499	0.000424754157537	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Abnormal eyelash morphology
HPA:0381202	0.000471783621848	0.454545454545	SMC1A PDS5B CDCA5 STAG2 WAPL	placenta; hofbauer cells[>=Medium]
HP:0025667	0.00053759504131	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Fetal neck anomaly
HPA:0380201	0.000570582578531	0.454545454545	SMC1A PDS5B WAPL STAG2 RAD21	placenta; endothelial cells[>=Low]
HP:0009660	0.00058934269429	0.272727272727	SMC1A SMC3 RAD21	Short phalanx of the thumb
HP:0000775	0.000632520994411	0.363636363636	SMC1A SMC3 STAG2 RAD21	Abnormality of the diaphragm
HP:0010026	0.000669432453084	0.272727272727	SMC1A SMC3 RAD21	Aplasia/Hypoplasia of the 1st metacarpal
HPA:0381201	0.000847565920123	0.454545454545	SMC1A PDS5B CDCA5 STAG2 WAPL	placenta; hofbauer cells[>=Low]
HP:0010009	0.000850644000044	0.272727272727	SMC1A SMC3 RAD21	Abnormal 1st metacarpal morphology
HP:0000527	0.000859201080643	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Long eyelashes
HP:0002557	0.00117926806831	0.272727272727	SMC1A SMC3 RAD21	Hypoplastic nipples
HPA:0570813	0.00121606546802	0.636363636364	SMC1A WAPL SMC1B SMC3 RAD21 STAG1 PDS5B	testis; spermatogonia cells[High]
HP:0009658	0.00143949837695	0.272727272727	SMC1A SMC3 RAD21	Aplasia/Hypoplasia of the phalanges of the thumb
HP:0012165	0.00158279750202	0.272727272727	SMC1A SMC3 RAD21	Oligodactyly
HP:0000059	0.00158279750202	0.272727272727	SMC1A SMC3 RAD21	Hypoplastic labia majora
HP:0009623	0.00158279750202	0.272727272727	SMC1A SMC3 RAD21	Proximal placement of thumb
HP:0008850	0.00173525804287	0.272727272727	SMC1A SMC3 RAD21	Severe postnatal growth retardation
HP:0000294	0.00184963396072	0.363636363636	SMC1A SMC3 STAG2 RAD21	Low anterior hairline
GO:0007059	0.00234129436698	0.545454545455	SMC1A WAPL SMC3 STAG1 CDCA5 STAG2	chromosome segregation
HP:0012881	0.00244227717206	0.272727272727	SMC1A SMC3 RAD21	Abnormal labia majora morphology
GO:1903047	0.00265189841342	0.636363636364	SMC1A WAPL SMC3 RAD21 STAG1 CDCA5 STAG2	mitotic cell cycle process
HP:0004209	0.00307533027575	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Clinodactyly of the 5th finger
HP:0009179	0.00311817762616	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Deviation of the 5th finger
GO:0072686	0.00313578652688	0.454545454545	STAG1 STAG2 SMC3 WAPL SMC1A	mitotic spindle
HP:0009603	0.0033180741515	0.272727272727	SMC1A SMC3 RAD21	Deviation of the thumb
HP:0000319	0.00378762452355	0.363636363636	SMC1A SMC3 STAG2 RAD21	Smooth philtrum
HP:0000498	0.00438027839181	0.272727272727	SMC1A SMC3 RAD21	Blepharitis
HP:0006709	0.00438027839181	0.272727272727	SMC1A SMC3 RAD21	Aplasia/Hypoplasia of the nipples
HP:0000664	0.00439259222176	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Synophrys
HP:0040019	0.00440850474037	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Finger clinodactyly
GO:0090307	0.004433303799	0.363636363636	STAG1 SMC3 STAG2 SMC1A	mitotic spindle assembly
HPA:0381203	0.00489158700409	0.363636363636	SMC1A WAPL STAG2 PDS5B	placenta; hofbauer cells[High]
GO:0003682	0.00508136456802	0.545454545455	SMC1A STAG2 CDCA5 RAD21 STAG1 REC8	chromatin binding
HP:0002219	0.00568416440142	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Facial hypertrichosis
HPA:0570781	0.00587670837561	0.636363636364	PDS5B USP13 SMC1B SMC3 RAD21 STAG1 REC8	testis; preleptotene spermatocytes[>=Low]
HP:0000066	0.005996833911	0.272727272727	SMC1A SMC3 RAD21	Labial hypoplasia
HP:0002553	0.00608059083431	0.363636363636	SMC1A SMC3 STAG2 RAD21	Highly arched eyebrow
HPA:0300202	0.00663135327128	0.454545454545	STAG1 PDS5B WAPL STAG2 RAD21	lung; endothelial cells[>=Medium]
HP:5200005	0.00674028008009	0.272727272727	SMC1A SMC3 RAD21	Abnormal pitch
HP:0000954	0.00693448973762	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Single transverse palmar crease
HP:0007598	0.00754229729563	0.272727272727	SMC1A SMC3 RAD21	Bilateral single transverse palmar creases
HP:0012815	0.00754229729563	0.272727272727	SMC1A SMC3 RAD21	Hypoplastic female external genitalia
HP:0000599	0.00803948240816	0.363636363636	SMC1A SMC3 STAG2 RAD21	Abnormality of the frontal hairline
HP:0004207	0.00832687030669	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Abnormal 5th finger morphology
HP:0001629	0.00870739822915	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Ventricular septal defect
HP:0002020	0.00870739822915	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Gastroesophageal reflux
HPA:0381221	0.00924925980294	0.363636363636	PDS5B CDCA5 STAG2 WAPL	placenta; syncytiotrophoblasts - microvilli[>=Low]
HP:0010438	0.00950946805994	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Abnormal ventricular septum morphology
GO:0000278	0.00976698516068	0.636363636364	SMC1A WAPL SMC3 RAD21 STAG1 CDCA5 STAG2	mitotic cell cycle
HP:0004097	0.00982479256704	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Deviation of finger
GO:0044877	0.0100155710693	0.727272727273	SMC1A REC8 STAG2 USP13 SMC3 RAD21 STAG1 CDCA5	protein-containing complex binding
HP:5200010	0.0103212579368	0.272727272727	SMC1A SMC3 RAD21	Abnormal Intonation
HP:0000058	0.0119337183919	0.272727272727	SMC1A SMC3 RAD21	Abnormal labia morphology
HPA:0570731	0.0121686285657	1.0	SMC1A REC8 WAPL USP13 SMC1B SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	testis; Leydig cells[>=Low]
HP:0001770	0.0123693323056	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Toe syndactyly
HP:0009484	0.0123967196782	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Deviation of the hand or of fingers of the hand
HP:0030084	0.0133171960651	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Clinodactyly
HP:0010490	0.01405194714	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Abnormality of the palmar creases
HP:0004404	0.0143054354783	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Abnormal nipple morphology
HP:0002827	0.0143054354783	0.363636363636	SMC1A SMC3 STAG2 RAD21	Hip dislocation
HP:0002974	0.0143310014287	0.272727272727	SMC1A SMC3 RAD21	Radioulnar synostosis
HP:0001360	0.0143310014287	0.272727272727	SMC1A STAG2 RAD21	Holoprosencephaly
HP:0003042	0.0149762475938	0.272727272727	SMC1A SMC3 RAD21	Elbow dislocation
HP:0001018	0.0153533081982	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Abnormal palmar dermatoglyphics
HP:0031434	0.0156403893733	0.272727272727	SMC1A SMC3 RAD21	Abnormal prosody
WP:WP3995	0.0159763787346	0.181818181818	RAD21 SMC3	Prion disease pathway
HP:0001956	0.0163236887013	0.272727272727	SMC1A SMC3 RAD21	Truncal obesity
HP:0002507	0.0171180788587	0.181818181818	SMC1A STAG2	Semilobar holoprosencephaly
HP:0009811	0.0173221080239	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Abnormality of the elbow
HPA:0300201	0.0177860897918	0.454545454545	STAG1 PDS5B WAPL STAG2 RAD21	lung; endothelial cells[>=Low]
HPA:0570782	0.018212843076	0.545454545455	PDS5B SMC1B SMC3 RAD21 STAG1 USP13	testis; preleptotene spermatocytes[>=Medium]
HP:0000729	0.0182316218688	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Autistic behavior
HPA:0630221	0.0184244361938	0.909090909091	SMC1A REC8 WAPL USP13 SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	cervix; squamous epithelial cells[>=Low]
HP:0000998	0.0207844479087	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Hypertrichosis
HP:0030310	0.0216651030937	0.272727272727	SMC1A SMC3 RAD21	Upper extremity joint dislocation
HP:0002983	0.0233784682603	0.272727272727	SMC1A SMC3 RAD21	Micromelia
HP:0009553	0.0251168753425	0.363636363636	SMC1A SMC3 STAG2 RAD21	Abnormality of the hairline
GO:0006996	0.0251340410919	0.909090909091	SMC1A WAPL REC8 SMC1B SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	organelle organization
HPA:0570761	0.025476572755	0.636363636364	WAPL SMC1B SMC3 RAD21 STAG1 REC8 PDS5B	testis; pachytene spermatocytes[>=Low]
HP:0000003	0.0261122982791	0.272727272727	SMC1A SMC3 RAD21	Multicystic kidney dysplasia
HP:0008628	0.0261311487161	0.181818181818	RAD21 STAG2	Abnormality of the stapes
HP:0000202	0.0267248110904	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Orofacial cleft
HP:5201015	0.0274327152148	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Craniofacial cleft
HP:0034058	0.0279323829039	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Abnormal fetal morphology
HPA:0301362	0.0280845686802	0.454545454545	STAG1 PDS5B WAPL STAG2 RAD21	lung; alveolar cells type I[>=Medium]
HPA:0180052	0.0282571117813	0.909090909091	SMC1A REC8 WAPL USP13 SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	epididymis; glandular cells[>=Medium]
HP:0000676	0.0290488213855	0.272727272727	STAG1 STAG2 SMC1A	Abnormality of the incisor
HP:0002230	0.0290488213855	0.272727272727	SMC1A SMC3 RAD21	Generalized hirsutism
REAC:R-HSA-597592	0.0292756297165	0.545454545455	SMC1A STAG2 SMC3 RAD21 STAG1 USP13	Post-translational protein modification
HPA:0381223	0.0293523988383	0.272727272727	PDS5B CDCA5 WAPL	placenta; syncytiotrophoblasts - microvilli[High]
HP:0000219	0.0309738461564	0.363636363636	SMC1A SMC3 STAG2 RAD21	Thin upper lip vermilion
HP:0000534	0.0322641808925	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Abnormal eyebrow morphology
HP:0007477	0.0328175781361	0.363636363636	STAG1 RAD21 SMC3 SMC1A	Abnormal dermatoglyphics
HP:0030311	0.0332908587951	0.363636363636	SMC1A SMC3 STAG2 RAD21	Lower extremity joint dislocation
HP:0200055	0.0332913902948	0.272727272727	SMC1A SMC3 RAD21	Small hand
HPA:0440000	0.0345756227042	0.909090909091	SMC1A REC8 WAPL USP13 SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	skeletal muscle
HPA:0440341	0.0345756227042	0.909090909091	SMC1A REC8 WAPL USP13 SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	skeletal muscle; myocytes[>=Low]
HP:0011361	0.0347408689328	0.363636363636	SMC1A SMC3 STAG2 RAD21	Congenital abnormal hair pattern
GO:0051225	0.0355365818471	0.363636363636	STAG1 SMC3 STAG2 SMC1A	spindle assembly
HP:0002021	0.0355574730579	0.272727272727	SMC1A SMC3 RAD21	Pyloric stenosis
HPA:0360052	0.0363552516873	0.818181818182	SMC1A WAPL USP13 SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	parathyroid gland; glandular cells[>=Medium]
HP:0000786	0.0367275982991	0.272727272727	SMC1A SMC3 RAD21	Primary amenorrhea
HP:0004400	0.0391432747849	0.272727272727	SMC1A SMC3 RAD21	Abnormality of the pylorus
HP:0010049	0.042959116133	0.272727272727	SMC1A SMC3 RAD21	Short metacarpal
HP:0001713	0.0442567818508	0.454545454545	STAG1 RAD21 SMC3 STAG2 SMC1A	Abnormal cardiac ventricle morphology
HPA:0570812	0.0447286981173	0.636363636364	SMC1A WAPL SMC1B SMC3 RAD21 STAG1 PDS5B	testis; spermatogonia cells[>=Medium]
HPA:0020052	0.0456338520433	0.909090909091	SMC1A REC8 WAPL USP13 SMC3 RAD21 STAG1 CDCA5 STAG2 PDS5B	adrenal gland; glandular cells[>=Medium]
HP:0002162	0.0470117442209	0.272727272727	SMC1A SMC3 RAD21	Low posterior hairline
HP:0030141	0.0470117442209	0.272727272727	SMC1A SMC3 RAD21	Abnormality of the posterior hairline
HPA:0570773	0.0491495156852	0.272727272727	STAG1 PDS5B RAD21	testis; peritubular cells[High]
HP:0009778	0.0498483602626	0.272727272727	SMC1A SMC3 RAD21	Short thumb



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?
STAG1	RAD21	1.0	0.542
RAD21	STAG2	1.0	0.52
SMC3	RAD21	1.0	0.688
SMC3	SMC1A	0.999	0.938
STAG1	STAG2	0.999	0.6
REC8	SMC1B	0.999
SMC1A	RAD21	0.999	0.694
SMC3	CDCA5	0.999	0.444
SMC3	STAG1	0.999	0.5
RAD21	SMC1B	0.998
SMC3	STAG2	0.998	0.624
CDCA5	RAD21	0.998	0.224
STAG1	PDS5B	0.998	0.77
CDCA5	SMC1A	0.997	0.336
RAD21	PDS5B	0.997	0.394
STAG1	SMC1A	0.997	0.564
SMC1A	STAG2	0.997	0.63
USP13	REC8	0.997
WAPL	RAD21	0.995	0.182
SMC1A	REC8	0.994
STAG1	WAPL	0.994	0.108
SMC3	REC8	0.993
WAPL	PDS5B	0.993	0.296
STAG1	USP13	0.99	0.122
PDS5B	STAG2	0.99	0.42
SMC3	SMC1B	0.99
SMC1A	PDS5B	0.988	0.746
CDCA5	SMC1B	0.988
SMC3	PDS5B	0.987	0.602
RAD21	REC8	0.987
WAPL	STAG2	0.987	0.488
CDCA5	STAG2	0.986	0.122
USP13	STAG2	0.983	0.088
CDCA5	PDS5B	0.983	0.17
USP13	RAD21	0.981	0.072
USP13	PDS5B	0.969	0.1
SMC1A	SMC1B	0.963
CDCA5	WAPL	0.934	0.086
STAG1	CDCA5	0.932	0.134
USP13	WAPL	0.914	0.134
SMC3	USP13	0.897	0.284
SMC3	WAPL	0.891	0.332
SMC1B	STAG2	0.813
USP13	SMC1A	0.804	0.168
USP13	CDCA5	0.781	0.072
SMC1A	WAPL	0.756	0.35
USP13	SMC1B	0.754
STAG1	SMC1B	0.422
WAPL	SMC1B	0.187
REC8	STAG2	0.17
SMC1B	PDS5B	0.134
WAPL	REC8	0.006





Related Complexes

Genename	Complexes
SMC3	huMAP3_00229.1 huMAP3_14972.1
STAG1	huMAP3_00229.1 huMAP3_14972.1
USP13	huMAP3_00229.1 huMAP3_14972.1
CDCA5	huMAP3_00229.1 huMAP3_14972.1
SMC1A	huMAP3_00229.1 huMAP3_14972.1
WAPL	huMAP3_00229.1 huMAP3_14972.1
RAD21	huMAP3_00229.1 huMAP3_14972.1
REC8	huMAP3_00229.1 huMAP3_14972.1
SMC1B	huMAP3_00229.1 huMAP3_14972.1
PDS5B	huMAP3_00229.1 huMAP3_11232.1
STAG2	huMAP3_00229.1 huMAP3_14972.1