hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00234.1
Complex Portal: CPX-15009
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MOK | MAPK/MAK/MRK overlapping kinase (EC 2.7.11.22) (MOK protein kinase) (Renal tumor antigen 1) (RAGE-1) | 5 | UniProt NCBI |
| COQ10B | Coenzyme Q-binding protein COQ10 homolog B, mitochondrial | 3 | UniProt NCBI |
| NEK5 | Serine/threonine-protein kinase Nek5 (EC 2.7.11.1) (Never in mitosis A-related kinase 5) (NimA-related protein kinase 5) | 3 | UniProt NCBI |
| PSKH1 | Serine/threonine-protein kinase H1 (EC 2.7.11.1) (Protein serine kinase H1) (PSK-H1) | 5 | UniProt NCBI |
| KMT5C | Histone-lysine N-methyltransferase KMT5C (Lysine N-methyltransferase 5C) (Lysine-specific methyltransferase 5C) (Suppressor of variegation 4-20 homolog 2) (Su(var)4-20 homolog 2) (Suv4-20h2) ([histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase KMT5B) (EC 2.1.1.361) | 5 | UniProt NCBI |
| FTL | Ferritin light chain (Ferritin L subunit) | 5 | UniProt NCBI |
| TRNP1 | TMF-regulated nuclear protein 1 | 3 | UniProt NCBI |
| ERCC6L2 | DNA excision repair protein ERCC-6-like 2 (EC 3.6.4.-) (DNA repair and recombination protein RAD26-like) | 5 | UniProt NCBI |
| AGTPBP1 | Cytosolic carboxypeptidase 1 (EC 3.4.17.-) (EC 3.4.17.24) (ATP/GTP-binding protein 1) (Nervous system nuclear protein induced by axotomy protein 1 homolog) (Protein deglutamylase CCP1) | 5 | UniProt NCBI |
| DUSP5 | Dual specificity protein phosphatase 5 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase hVH3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0025331 | 0.0201617678902 | 0.222222222222 | AGTPBP1 FTL | Upgaze palsy |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| FTL | AGTPBP1 | 0.997 | 0.243090909091 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KMT5C | FTL | 0.994 | 0.126 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MOK | FTL | 0.992 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PSKH1 | FTL | 0.991 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| COQ10B | FTL | 0.988 | 0.178 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FTL | DUSP5 | 0.979 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| FTL | ERCC6L2 | 0.974 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| NEK5 | FTL | 0.964 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| FTL | TRNP1 | 0.953 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| COQ10B | KMT5C | 0.946 | 0.094 | bioplex3_WMM WMM_only | |
| COQ10B | PSKH1 | 0.946 | bioplex3_WMM WMM_only | ||
| MOK | COQ10B | 0.931 | bioplex3_WMM WMM_only | ||
| MOK | NEK5 | 0.904 | bioplex3_WMM WMM_only | ||
| KMT5C | ERCC6L2 | 0.902 | bioplex3_WMM WMM_only | ||
| NEK5 | PSKH1 | 0.902 | bioplex3_WMM WMM_only | ||
| NEK5 | KMT5C | 0.902 | bioplex3_WMM WMM_only | ||
| PSKH1 | ERCC6L2 | 0.902 | bioplex3_WMM WMM_only | ||
| COQ10B | NEK5 | 0.902 | bioplex3_WMM WMM_only | ||
| COQ10B | ERCC6L2 | 0.902 | bioplex3_WMM WMM_only | ||
| NEK5 | ERCC6L2 | 0.902 | bioplex3_WMM WMM_only | ||
| ERCC6L2 | DUSP5 | 0.902 | bioplex3_WMM WMM_only | ||
| KMT5C | TRNP1 | 0.902 | bioplex3_WMM WMM_only | ||
| NEK5 | DUSP5 | 0.902 | bioplex3_WMM WMM_only | ||
| COQ10B | TRNP1 | 0.902 | bioplex3_WMM WMM_only | ||
| KMT5C | DUSP5 | 0.902 | bioplex3_WMM WMM_only | ||
| TRNP1 | DUSP5 | 0.902 | bioplex3_WMM WMM_only | ||
| PSKH1 | TRNP1 | 0.902 | bioplex3_WMM WMM_only | ||
| MOK | ERCC6L2 | 0.902 | bioplex3_WMM WMM_only | ||
| COQ10B | DUSP5 | 0.902 | bioplex3_WMM WMM_only | ||
| PSKH1 | DUSP5 | 0.902 | bioplex3_WMM WMM_only | ||
| TRNP1 | ERCC6L2 | 0.902 | bioplex3_WMM WMM_only | ||
| NEK5 | TRNP1 | 0.902 | bioplex3_WMM WMM_only | ||
| MOK | KMT5C | 0.897 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ERCC6L2 | AGTPBP1 | 0.892 | bioplex3_WMM WMM_only | ||
| COQ10B | AGTPBP1 | 0.826 | 0.096 | bioplex3_WMM WMM_only | |
| MOK | PSKH1 | 0.804 | bioplex3_WMM WMM_only | ||
| PSKH1 | AGTPBP1 | 0.804 | bioplex3_WMM WMM_only | ||
| KMT5C | AGTPBP1 | 0.804 | 0.15 | bioplex3_WMM WMM_only | |
| PSKH1 | KMT5C | 0.793 | bioplex3_WMM WMM_only | ||
| TRNP1 | AGTPBP1 | 0.768 | bioplex3_WMM WMM_only | ||
| NEK5 | AGTPBP1 | 0.768 | bioplex3_WMM WMM_only | ||
| MOK | TRNP1 | 0.722 | bioplex3_WMM WMM_only | ||
| AGTPBP1 | DUSP5 | 0.715 | bioplex3_WMM WMM_only | ||
| MOK | AGTPBP1 | 0.561 | bioplex3_WMM WMM_only | ||
| MOK | DUSP5 | 0.478 | bioplex3_WMM WMM_only |
Related Complexes