hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00241.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CALR | Calreticulin (CRP55) (Calregulin) (Endoplasmic reticulum resident protein 60) (ERp60) (HACBP) (grp60) | 5 | UniProt NCBI |
| CTSK | Cathepsin K (EC 3.4.22.38) (Cathepsin O) (Cathepsin O2) (Cathepsin X) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5217 | 0.0249718442457 | 0.5 | CALR | Calreticulin homo-oligomer complex |
| HP:0001433 | 0.030911500096 | 1.0 | CALR CTSK | Hepatosplenomegaly |
| REAC:R-HSA-168316 | 0.0499419797295 | 0.5 | CALR | Assembly of Viral Components at the Budding Site |
| REAC:R-HSA-168268 | 0.0499419797295 | 0.5 | CALR | Virus Assembly and Release |
| HP:0005906 | 0.0499436884913 | 0.5 | CTSK | Delayed pneumatization of the mastoid process |
| HP:0008598 | 0.0499436884913 | 0.5 | CTSK | Mild conductive hearing impairment |
| HP:0010884 | 0.0499436884913 | 0.5 | CTSK | Acromelia |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| CALR | CTSK | 0.984 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes
| Genename | Complexes |
|---|---|
| CALR | huMAP3_00241.1 huMAP3_14354.1 huMAP3_14946.1 |
| CTSK | huMAP3_00241.1 huMAP3_04155.1 huMAP3_12066.1 |