hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
MITD1	MIT domain-containing protein 1	5	UniProt NCBI
LIN7A	Protein lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Tax interaction protein 33) (TIP-33) (Vertebrate lin-7 homolog 1) (Veli-1)	5	UniProt NCBI
APBA1	Amyloid-beta A4 precursor protein-binding family A member 1 (Adapter protein X11alpha) (Neuron-specific X11 protein) (Neuronal Munc18-1-interacting protein 1) (Mint-1)	5	UniProt NCBI
DLG4	Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)	5	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-9609736	1.18162330858e-05	0.75	APBA1 LIN7A DLG4	Assembly and cell surface presentation of NMDA receptors
REAC:R-HSA-6794361	2.12537496865e-05	0.75	APBA1 LIN7A DLG4	Neurexins and neuroligins
CORUM:3207	3.07520988333e-05	0.5	APBA1 LIN7A	LIN2-LIN7-SAP97-MINT1 complex
REAC:R-HSA-6794362	7.65476877178e-05	0.75	APBA1 LIN7A DLG4	Protein-protein interactions at synapses
REAC:R-HSA-442755	0.000114832276301	0.75	APBA1 LIN7A DLG4	Activation of NMDA receptors and postsynaptic events
REAC:R-HSA-112314	0.000897810107574	0.75	APBA1 LIN7A DLG4	Neurotransmitter receptors and postsynaptic signal transmission
REAC:R-HSA-112315	0.00190780632503	0.75	APBA1 LIN7A DLG4	Transmission across Chemical Synapses
REAC:R-HSA-212676	0.00214930898727	0.5	APBA1 LIN7A	Dopamine Neurotransmitter Release Cycle
REAC:R-HSA-112316	0.00603406960129	0.75	APBA1 LIN7A DLG4	Neuronal System
REAC:R-HSA-112310	0.00718390333861	0.5	APBA1 LIN7A	Neurotransmitter release cycle
WP:WP5417	0.0092628309276	0.5	DLG4 LIN7A	Cell lineage map for neuronal differentiation
CORUM:1909	0.0249718442456	0.25	DLG4	APC-DLG4 complex
CORUM:6321	0.0249718442456	0.25	DLG4	DLG4-DLGAP1-SHANK3 complex
CORUM:1089	0.049938562206	0.25	LIN7A	VAM1-VELI1 complex
CORUM:3208	0.049938562206	0.25	LIN7A	LIN2-LIN7 complex
CORUM:7234	0.049938562206	0.25	DLG4	DLGAP1-DLG4-DYNLL2 complex

Protein 1	Protein 2	Score	ProteomeHD	Evidence
MITD1	APBA1	0.989	0.092	bioplex3_HEK293 bioplex3_WMM WMM_only
APBA1	DLG4	0.981	0.106	bioplex3_WMM bioplex3_HCT116 WMM_only
LIN7A	APBA1	0.974	0.152	bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only
LIN7A	DLG4	0.356	0.104	bioplex3_WMM WMM_only
MITD1	DLG4	0.214	0.106	bioplex3_WMM WMM_only
MITD1	LIN7A	0.091	0.074	bioplex3_WMM WMM_only

Genename	Complexes
MITD1	huMAP3_00243.1 huMAP3_00738.1 huMAP3_02301.1 huMAP3_05627.1 huMAP3_13728.1 huMAP3_13805.1
LIN7A	huMAP3_00243.1 huMAP3_05314.1 huMAP3_06839.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_10716.1 huMAP3_11195.1 huMAP3_14575.1
APBA1	huMAP3_00243.1 huMAP3_05627.1 huMAP3_06620.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_11195.1 huMAP3_14575.1
DLG4	huMAP3_00243.1 huMAP3_05036.1 huMAP3_05627.1 huMAP3_06620.1 huMAP3_08198.1 huMAP3_08481.1 huMAP3_09519.1 huMAP3_11195.1 huMAP3_11270.1 huMAP3_14575.1