hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00261.1
Complex Portal: CPX-19114
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ATP5PO | ATP synthase subunit O, mitochondrial (ATP synthase peripheral stalk subunit OSCP) (Oligomycin sensitivity conferral protein) (OSCP) | 5 | UniProt NCBI |
| ACKR3 | Atypical chemokine receptor 3 (C-X-C chemokine receptor type 7) (CXC-R7) (CXCR-7) (Chemokine orphan receptor 1) (G-protein coupled receptor 159) (G-protein coupled receptor RDC1 homolog) (RDC-1) | 5 | UniProt NCBI |
| ATP5MK | ATP synthase membrane subunit K, mitochondrial (ATP synthase membrane subunit DAPIT, mitochondrial) (Diabetes-associated protein in insulin-sensitive tissues) (HCV F-transactivated protein 2) (Up-regulated during skeletal muscle growth protein 5) | 5 | UniProt NCBI |
| ATP5F1A | ATP synthase subunit alpha, mitochondrial (ATP synthase F1 subunit alpha) | 5 | UniProt NCBI |
| ATP5MF | ATP synthase subunit f, mitochondrial (ATP synthase membrane subunit f) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0005753 | 0.000127839654632 | 1.0 | ATP5PO ATP5MF ATP5MK | mitochondrial proton-transporting ATP synthase complex |
| GO:0045259 | 0.000127839654632 | 1.0 | ATP5PO ATP5MF ATP5MK | proton-transporting ATP synthase complex |
| CORUM:563 | 0.000225453649047 | 0.666666666667 | ATP5PO ATP5MF | F1F0-ATP synthase, mitochondrial |
| REAC:R-HSA-163210 | 0.00104246243986 | 0.666666666667 | ATP5PO ATP5MF | Formation of ATP by chemiosmotic coupling |
| GO:0016469 | 0.00127301382402 | 1.0 | ATP5PO ATP5MF ATP5MK | proton-transporting two-sector ATPase complex |
| WP:WP623 | 0.00193308448658 | 0.666666666667 | ATP5PO ATP5MF | Oxidative phosphorylation |
| REAC:R-HSA-8949613 | 0.00296224002415 | 0.666666666667 | ATP5PO ATP5MF | Cristae formation |
| GO:0015986 | 0.00526161104852 | 1.0 | ATP5PO ATP5MF ATP5MK | proton motive force-driven ATP synthesis |
| WP:WP111 | 0.00536035090333 | 0.666666666667 | ATP5PO ATP5MF | Electron transport chain OXPHOS system in mitochondria |
| KEGG:00190 | 0.0056035932516 | 0.666666666667 | ATP5PO ATP5MF | Oxidative phosphorylation |
| GO:0006754 | 0.00851239083773 | 1.0 | ATP5PO ATP5MF ATP5MK | ATP biosynthetic process |
| GO:0009145 | 0.00915870199393 | 1.0 | ATP5PO ATP5MF ATP5MK | purine nucleoside triphosphate biosynthetic process |
| GO:0009206 | 0.00915870199393 | 1.0 | ATP5PO ATP5MF ATP5MK | purine ribonucleoside triphosphate biosynthetic process |
| GO:0009201 | 0.0109157763448 | 1.0 | ATP5PO ATP5MF ATP5MK | ribonucleoside triphosphate biosynthetic process |
| GO:0009142 | 0.0120707547584 | 1.0 | ATP5PO ATP5MF ATP5MK | nucleoside triphosphate biosynthetic process |
| KEGG:04714 | 0.0158142547588 | 0.666666666667 | ATP5PO ATP5MF | Thermogenesis |
| REAC:R-HSA-1592230 | 0.0248259565326 | 0.666666666667 | ATP5PO ATP5MF | Mitochondrial biogenesis |
| GO:1904949 | 0.042099520671 | 1.0 | ATP5PO ATP5MF ATP5MK | ATPase complex |
| REAC:R-HSA-163200 | 0.049233254294 | 0.666666666667 | ATP5PO ATP5MF | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| GO:0098800 | 0.0498541011049 | 1.0 | ATP5PO ATP5MF ATP5MK | inner mitochondrial membrane protein complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ATP5F1A | ATP5MF | 0.999 | 0.836 | hein_WMM bioplex_WMM Guru bioplex3_WMM boldt fraction boldt_WMM | |
| ATP5PO | ATP5F1A | 0.999 | 0.93 |
structurally_consistent (dimer)
|
hein_WMM bioplex_WMM Guru bioplex3_WMM boldt hein () fraction boldt_WMM treiber_WMM |
| ATP5PO | ATP5MF | 0.982 | 0.952 | bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM treiber_WMM WMM_only | |
| ATP5PO | ATP5MK | 0.978 | 0.562 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only | |
| ATP5MK | ATP5F1A | 0.977 | 0.756 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| ATP5PO | ACKR3 | 0.977 | 0.096 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () | |
| ATP5MK | ATP5MF | 0.955 | 0.708 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only | |
| ACKR3 | ATP5F1A | 0.937 | 0.144 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () | |
| ACKR3 | ATP5MF | 0.286 | 0.062 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes