hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00267.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SEC16B | Protein transport protein Sec16B (Leucine zipper transcription regulator 2) (Regucalcin gene promoter region-related protein p117) (RGPR-p117) (SEC16 homolog B) | 5 | UniProt NCBI |
| SCYL1 | N-terminal kinase-like protein (Coated vesicle-associated kinase of 90 kDa) (SCY1-like protein 1) (Telomerase regulation-associated protein) (Telomerase transcriptional element-interacting factor) (Teratoma-associated tyrosine kinase) | 5 | UniProt NCBI |
| SEC31A | Protein transport protein Sec31A (ABP125) (ABP130) (SEC31-like protein 1) (SEC31-related protein A) (Web1-like protein) | 5 | UniProt NCBI |
| SEC13 | Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-204005 | 5.03512663474e-05 | 0.75 | SEC16B SEC13 SEC31A | COPII-mediated vesicle transport |
| GO:0030662 | 0.000491307867445 | 1.0 | SEC31A SEC16B SEC13 SCYL1 | coated vesicle membrane |
| REAC:R-HSA-199977 | 0.000664788606793 | 0.75 | SEC16B SEC13 SEC31A | ER to Golgi Anterograde Transport |
| REAC:R-HSA-948021 | 0.00115920951182 | 0.75 | SEC16B SEC13 SEC31A | Transport to the Golgi and subsequent modification |
| GO:0030135 | 0.00263891757684 | 1.0 | SEC31A SEC16B SEC13 SCYL1 | coated vesicle |
| REAC:R-HSA-983170 | 0.00359044851421 | 0.5 | SEC31A SEC13 | Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| REAC:R-HSA-446203 | 0.00516924519396 | 0.75 | SEC16B SEC13 SEC31A | Asparagine N-linked glycosylation |
| GO:0048193 | 0.00569790407237 | 1.0 | SEC31A SEC16B SEC13 SCYL1 | Golgi vesicle transport |
| WP:WP1982 | 0.00578263137464 | 0.5 | SEC31A SEC13 | Sterol regulatory element binding proteins SREBP signaling |
| GO:0012507 | 0.00663460918661 | 0.75 | SEC16B SEC13 SEC31A | ER to Golgi transport vesicle membrane |
| GO:0030120 | 0.0112187083505 | 0.75 | SCYL1 SEC13 SEC31A | vesicle coat |
| GO:0030134 | 0.0238272099283 | 0.75 | SEC16B SEC13 SEC31A | COPII-coated ER to Golgi transport vesicle |
| KEGG:04141 | 0.0298999303213 | 0.5 | SEC31A SEC13 | Protein processing in endoplasmic reticulum |
| GO:0048475 | 0.0405772675542 | 0.75 | SCYL1 SEC13 SEC31A | coated membrane |
| GO:0030117 | 0.0405772675542 | 0.75 | SCYL1 SEC13 SEC31A | membrane coat |
| REAC:R-HSA-199991 | 0.0424877030349 | 0.75 | SEC16B SEC13 SEC31A | Membrane Trafficking |
| REAC:R-HSA-5653656 | 0.0499402458571 | 0.75 | SEC16B SEC13 SEC31A | Vesicle-mediated transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| SEC31A | SEC13 | 1.0 | 0.29 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction |
| SCYL1 | SEC31A | 0.998 | 0.262 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM treiber_WMM |
| SEC16B | SEC13 | 0.997 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| SCYL1 | SEC13 | 0.968 | 0.142 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
Related Complexes