hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00334.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FKTN | Ribitol-5-phosphate transferase FKTN (EC 2.7.8.-) (Fukutin) (Fukuyama-type congenital muscular dystrophy protein) (Ribitol-5-phosphate transferase) | 5 | UniProt NCBI |
| RXYLT1 | Ribitol-5-phosphate xylosyltransferase 1 (EC 2.4.2.61) (Transmembrane protein 5) (UDP-D-xylose:ribitol-5-phosphate beta1,4-xylosyltransferase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00515 | 3.75535994234e-05 | 1.0 | FKTN RXYLT1 | Mannose type O-glycan biosynthesis |
| HP:0007260 | 0.000358839967947 | 1.0 | FKTN RXYLT1 | Type II lissencephaly |
| HP:0007731 | 0.000649329465809 | 1.0 | FKTN RXYLT1 | Chorioretinal dysplasia |
| HP:0007227 | 0.000649329465809 | 1.0 | FKTN RXYLT1 | Macrogyria |
| HP:0010508 | 0.000789447929484 | 1.0 | FKTN RXYLT1 | Metatarsus valgus |
| HP:0007033 | 0.000864633446577 | 1.0 | FKTN RXYLT1 | Cerebellar dysplasia |
| HP:0012400 | 0.000943236487175 | 1.0 | FKTN RXYLT1 | Abnormal circulating aldolase concentration |
| HP:0007973 | 0.000943236487175 | 1.0 | FKTN RXYLT1 | Retinal dysplasia |
| HP:0001460 | 0.00280236927349 | 1.0 | FKTN RXYLT1 | Aplasia/Hypoplasia involving the skeletal musculature |
| HP:0001331 | 0.00584738271579 | 1.0 | FKTN RXYLT1 | Absent septum pellucidum |
| HP:0000528 | 0.00667442340382 | 1.0 | FKTN RXYLT1 | Anophthalmia |
| HP:0000176 | 0.0077851185427 | 1.0 | FKTN RXYLT1 | Submucous cleft hard palate |
| HP:0410005 | 0.00801751014099 | 1.0 | FKTN RXYLT1 | Cleft hard palate |
| HP:0003560 | 0.00873519007688 | 1.0 | FKTN RXYLT1 | Muscular dystrophy |
| HP:5201016 | 0.00948362772432 | 1.0 | FKTN RXYLT1 | Submucous cleft palate |
| HP:0100737 | 0.00973994198714 | 1.0 | FKTN RXYLT1 | Abnormal hard palate morphology |
| HP:0045040 | 0.011629832485 | 1.0 | FKTN RXYLT1 | Abnormal circulating lactate dehydrogenase concentration |
| HP:0007375 | 0.0146201655512 | 1.0 | FKTN RXYLT1 | Abnormal septum pellucidum morphology |
| HP:0000541 | 0.0146201655512 | 1.0 | FKTN RXYLT1 | Retinal detachment |
| HP:0000482 | 0.0227948817734 | 1.0 | FKTN RXYLT1 | Microcornea |
| HP:0001305 | 0.026485807158 | 1.0 | FKTN RXYLT1 | Dandy-Walker malformation |
| HP:0001832 | 0.0286559345832 | 1.0 | FKTN RXYLT1 | Abnormal metatarsal morphology |
| HP:0000532 | 0.0332525036964 | 1.0 | FKTN RXYLT1 | Abnormal chorioretinal morphology |
| HP:0000193 | 0.0332525036964 | 1.0 | FKTN RXYLT1 | Bifid uvula |
| HP:0010950 | 0.0351868219998 | 1.0 | FKTN RXYLT1 | Abnormal fourth ventricle morphology |
| HP:0002198 | 0.0351868219998 | 1.0 | FKTN RXYLT1 | Dilated fourth ventricle |
| HP:0002350 | 0.0376816141579 | 1.0 | FKTN RXYLT1 | Cerebellar cyst |
| HP:0001302 | 0.0376816141579 | 1.0 | FKTN RXYLT1 | Pachygyria |
| HP:0001120 | 0.0413178591665 | 1.0 | FKTN RXYLT1 | Abnormality of corneal size |
| GO:0035269 | 0.0426062655276 | 1.0 | FKTN RXYLT1 | protein O-linked mannosylation |
| GO:0035268 | 0.0426062655276 | 1.0 | FKTN RXYLT1 | protein mannosylation |
| HP:0000612 | 0.0440177027348 | 1.0 | FKTN RXYLT1 | Iris coloboma |
| HP:0000610 | 0.0473702932925 | 1.0 | FKTN RXYLT1 | Abnormal choroid morphology |
| HP:0001339 | 0.0479410197177 | 1.0 | FKTN RXYLT1 | Lissencephaly |
| HP:0000172 | 0.0479410197177 | 1.0 | FKTN RXYLT1 | Abnormal uvula morphology |
| HP:0005445 | 0.0490927251387 | 1.0 | FKTN RXYLT1 | Enlarged posterior fossa |
| GO:0097502 | 0.0491610756088 | 1.0 | FKTN RXYLT1 | mannosylation |
| HP:0007348 | 0.0499436884913 | 0.5 | FKTN | Hypoplasia of the pyramidal tract |
| HP:0009060 | 0.0499436884913 | 0.5 | FKTN | Scapular muscle atrophy |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| FKTN | RXYLT1 | 0.991 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| FKTN | huMAP3_00334.1 huMAP3_12644.1 huMAP3_13422.1 |
| RXYLT1 | huMAP3_00334.1 |