hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00349.1
Complex Portal: CPX-22180
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PTBP1 | Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I) | 5 | UniProt NCBI |
| PTBP3 | Polypyrimidine tract-binding protein 3 (Regulator of differentiation 1) (Rod1) | 5 | UniProt NCBI |
| TRIM25 | E3 ubiquitin/ISG15 ligase TRIM25 (EC 6.3.2.n3) (Estrogen-responsive finger protein) (RING finger protein 147) (RING-type E3 ubiquitin transferase) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase TRIM25) (Tripartite motif-containing protein 25) (Ubiquitin/ISG15-conjugating enzyme TRIM25) (Zinc finger protein 147) | 5 | UniProt NCBI |
| PTBP2 | Polypyrimidine tract-binding protein 2 (Neural polypyrimidine tract-binding protein) (Neurally-enriched homolog of PTB) (PTB-like protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:2717 | 0.0249718442456 | 0.333333333333 | TRIM25 | Ubiquitin E3 ligase (TRIM25, DDX58) |
| CORUM:7357 | 0.0499402709677 | 0.333333333333 | TRIM25 | TRIM25-G3BP2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PTBP1 | PTBP3 | 0.982 | 0.168 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 fraction treiber_WMM | |
| PTBP3 | PTBP2 | 0.975 | 0.088 | bioplex3_HEK293 bioplex3_WMM youn_WMM bioplex3_HCT116 treiber_WMM WMM_only | |
| PTBP3 | TRIM25 | 0.954 | 0.19 | bioplex_WMM bioplex3_WMM youn_WMM fraction treiber_WMM | |
| PTBP1 | TRIM25 | 0.252 | 0.752 | youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM | |
| PTBP1 | PTBP2 | 0.185 | 0.12 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only treiber_WMM | |
| TRIM25 | PTBP2 | 0.006 | 0.314923076923 | bioplex3_WMM youn_WMM fraction |
Related Complexes