hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00356.1
Complex Portal: CPX-23618
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PSMB8 | Proteasome subunit beta type-8 (EC 3.4.25.1) (Low molecular mass protein 7) (Macropain subunit C13) (Multicatalytic endopeptidase complex subunit C13) (Proteasome component C13) (Proteasome subunit beta-5i) (Really interesting new gene 10 protein) | 5 | UniProt NCBI |
| PSMA3 | Proteasome subunit alpha type-3 (Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8) (Proteasome component C8) | 5 | UniProt NCBI |
| PSMB2 | Proteasome subunit beta type-2 (Macropain subunit C7-I) (Multicatalytic endopeptidase complex subunit C7-I) (Proteasome component C7-I) | 5 | UniProt NCBI |
| PSME4 | Proteasome activator complex subunit 4 (Proteasome activator PA200) | 5 | UniProt NCBI |
| AKIRIN2 | Akirin-2 | 5 | UniProt NCBI |
| PSMA6 | Proteasome subunit alpha type-6 (27 kDa prosomal protein) (PROS-27) (p27K) (Macropain iota chain) (Multicatalytic endopeptidase complex iota chain) (Proteasome iota chain) | 5 | UniProt NCBI |
| PSMA4 | Proteasome subunit alpha type-4 (Macropain subunit C9) (Multicatalytic endopeptidase complex subunit C9) (Proteasome component C9) (Proteasome subunit L) | 5 | UniProt NCBI |
| PSMB7 | Proteasome subunit beta type-7 (EC 3.4.25.1) (Macropain chain Z) (Multicatalytic endopeptidase complex chain Z) (Proteasome subunit Z) | 5 | UniProt NCBI |
| PSMB9 | Proteasome subunit beta type-9 (EC 3.4.25.1) (Low molecular mass protein 2) (Macropain chain 7) (Multicatalytic endopeptidase complex chain 7) (Proteasome chain 7) (Proteasome subunit beta-1i) (Really interesting new gene 12 protein) | 5 | UniProt NCBI |
| PSMG4 | Proteasome assembly chaperone 4 (PAC-4) (hPAC4) | 3 | UniProt NCBI |
| PSME1 | Proteasome activator complex subunit 1 (11S regulator complex subunit alpha) (REG-alpha) (Activator of multicatalytic protease subunit 1) (Interferon gamma up-regulated I-5111 protein) (IGUP I-5111) (Proteasome activator 28 subunit alpha) (PA28a) (PA28alpha) | 5 | UniProt NCBI |
| PSME2 | Proteasome activator complex subunit 2 (11S regulator complex subunit beta) (REG-beta) (Activator of multicatalytic protease subunit 2) (Proteasome activator 28 subunit beta) (PA28b) (PA28beta) | 5 | UniProt NCBI |
| RNF181 | E3 ubiquitin-protein ligase RNF181 (EC 2.3.2.27) (RING finger protein 181) | 5 | UniProt NCBI |
| PSMB6 | Proteasome subunit beta type-6 (EC 3.4.25.1) (Macropain delta chain) (Multicatalytic endopeptidase complex delta chain) (Proteasome delta chain) (Proteasome subunit Y) | 5 | UniProt NCBI |
| PSMB4 | Proteasome subunit beta type-4 (26 kDa prosomal protein) (HsBPROS26) (PROS-26) (Macropain beta chain) (Multicatalytic endopeptidase complex beta chain) (Proteasome beta chain) (Proteasome chain 3) (HsN3) | 5 | UniProt NCBI |
| PSMB5 | Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X) | 5 | UniProt NCBI |
| AKIRIN1 | Akirin-1 | 5 | UniProt NCBI |
| PSMG1 | Proteasome assembly chaperone 1 (PAC-1) (Chromosome 21 leucine-rich protein) (C21-LRP) (Down syndrome critical region protein 2) | 5 | UniProt NCBI |
| PSMA7 | Proteasome subunit alpha type-7 (Proteasome subunit RC6-1) (Proteasome subunit XAPC7) | 5 | UniProt NCBI |
| PSMG2 | Proteasome assembly chaperone 2 (PAC-2) (Hepatocellular carcinoma-susceptibility protein 3) (Tumor necrosis factor superfamily member 5-induced protein 1) | 5 | UniProt NCBI |
| PSMG3 | Proteasome assembly chaperone 3 (PAC-3) (hPAC3) | 3 | UniProt NCBI |
| PSMB1 | Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain) | 5 | UniProt NCBI |
| POMP | Proteasome maturation protein (Proteassemblin) (Protein UMP1 homolog) (hUMP1) (Voltage-gated K channel beta subunit 4.1) | 5 | UniProt NCBI |
| FBXO7 | F-box only protein 7 | 5 | UniProt NCBI |
| PSMF1 | Proteasome inhibitor PI31 subunit (hPI31) | 5 | UniProt NCBI |
| PSMA1 | Proteasome subunit alpha type-1 (30 kDa prosomal protein) (PROS-30) (Macropain subunit C2) (Multicatalytic endopeptidase complex subunit C2) (Proteasome component C2) (Proteasome nu chain) | 5 | UniProt NCBI |
| PSMA5 | Proteasome subunit alpha type-5 (Macropain zeta chain) (Multicatalytic endopeptidase complex zeta chain) (Proteasome zeta chain) | 5 | UniProt NCBI |
| PSMA8 | Proteasome subunit alpha-type 8 (Proteasome alpha 4 subunit) (Alpha4s) (Proteasome subunit alpha-type 7-like) | 4 | UniProt NCBI |
| PSME3IP1 | PSME3-interacting protein (NEFA-interacting nuclear protein NIP30) (PA28G-interacting protein) | 5 | UniProt NCBI |
| PSMB10 | Proteasome subunit beta type-10 (EC 3.4.25.1) (Low molecular mass protein 10) (Macropain subunit MECl-1) (Multicatalytic endopeptidase complex subunit MECl-1) (Proteasome MECl-1) (Proteasome subunit beta-2i) | 5 | UniProt NCBI |
| PSMA2 | Proteasome subunit alpha type-2 (Macropain subunit C3) (Multicatalytic endopeptidase complex subunit C3) (Proteasome component C3) | 5 | UniProt NCBI |
| PSME3 | Proteasome activator complex subunit 3 (11S regulator complex subunit gamma) (REG-gamma) (Activator of multicatalytic protease subunit 3) (Ki nuclear autoantigen) (Proteasome activator 28 subunit gamma) (PA28g) (PA28gamma) | 5 | UniProt NCBI |
| PSMB3 | Proteasome subunit beta type-3 (Proteasome chain 13) (Proteasome component C10-II) (Proteasome theta chain) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03050 | 6.06709214475e-47 | 0.7 | PSMA6 POMP PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Proteasome |
| REAC:R-HSA-1236978 | 1.22214135765e-42 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Cross-presentation of soluble exogenous antigens (endosomes) |
| REAC:R-HSA-211733 | 3.53536906305e-42 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Regulation of activated PAK-2p34 by proteasome mediated degradation |
| REAC:R-HSA-350562 | 5.88842968719e-42 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Regulation of ornithine decarboxylase (ODC) |
| REAC:R-HSA-349425 | 9.68108301923e-42 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Autodegradation of the E3 ubiquitin ligase COP1 |
| REAC:R-HSA-69613 | 9.68108301923e-42 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | p53-Independent G1/S DNA damage checkpoint |
| REAC:R-HSA-69610 | 9.68108301923e-42 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | p53-Independent DNA Damage Response |
| REAC:R-HSA-69601 | 9.68108301923e-42 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Ubiquitin Mediated Degradation of Phosphorylated Cdc25A |
| REAC:R-HSA-75815 | 9.68108301923e-42 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Ubiquitin-dependent degradation of Cyclin D |
| REAC:R-HSA-180534 | 9.68108301923e-42 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Vpu mediated degradation of CD4 |
| REAC:R-HSA-450408 | 1.57214739367e-41 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | AUF1 (hnRNP D0) binds and destabilizes mRNA |
| REAC:R-HSA-169911 | 1.57214739367e-41 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Regulation of Apoptosis |
| REAC:R-HSA-180585 | 1.57214739367e-41 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Vif-mediated degradation of APOBEC3G |
| REAC:R-HSA-8854050 | 2.52331298126e-41 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | FBXL7 down-regulates AURKA during mitotic entry and in early mitosis |
| REAC:R-HSA-174113 | 4.00499408199e-41 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | SCF-beta-TrCP mediated degradation of Emi1 |
| REAC:R-HSA-5362768 | 4.00499408199e-41 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Hh mutants are degraded by ERAD |
| REAC:R-HSA-4641257 | 4.00499408199e-41 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Degradation of AXIN |
| REAC:R-HSA-5387390 | 6.28944638927e-41 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Hh mutants abrogate ligand secretion |
| REAC:R-HSA-4641258 | 9.77718478767e-41 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Degradation of DVL |
| REAC:R-HSA-351202 | 9.77718478767e-41 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Metabolism of polyamines |
| REAC:R-HSA-69541 | 9.77718478767e-41 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Stabilization of p53 |
| REAC:R-HSA-5610780 | 2.2959533117e-40 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Degradation of GLI1 by the proteasome |
| REAC:R-HSA-5676590 | 2.2959533117e-40 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | NIK-->noncanonical NF-kB signaling |
| REAC:R-HSA-5358346 | 2.2959533117e-40 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Hedgehog ligand biogenesis |
| REAC:R-HSA-5610785 | 3.47109324148e-40 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | GLI3 is processed to GLI3R by the proteasome |
| REAC:R-HSA-5610783 | 3.47109324148e-40 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Degradation of GLI2 by the proteasome |
| REAC:R-HSA-5678895 | 3.47109324148e-40 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Defective CFTR causes cystic fibrosis |
| REAC:R-HSA-5607761 | 3.47109324148e-40 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Dectin-1 mediated noncanonical NF-kB signaling |
| REAC:R-HSA-5658442 | 7.73633217063e-40 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Regulation of RAS by GAPs |
| GO:0000502 | 1.42311920383e-39 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | proteasome complex |
| REAC:R-HSA-4608870 | 1.67101796838e-39 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Asymmetric localization of PCP proteins |
| REAC:R-HSA-1234176 | 1.67101796838e-39 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha |
| REAC:R-HSA-69580 | 2.42898117638e-39 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | p53-Dependent G1/S DNA damage checkpoint |
| REAC:R-HSA-69563 | 2.42898117638e-39 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | p53-Dependent G1 DNA Damage Response |
| REAC:R-HSA-1169091 | 3.50623245729e-39 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Activation of NF-kappaB in B cells |
| REAC:R-HSA-8939902 | 3.50623245729e-39 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Regulation of RUNX2 expression and activity |
| REAC:R-HSA-174154 | 5.02738916667e-39 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | APC/C:Cdc20 mediated degradation of Securin |
| REAC:R-HSA-69615 | 5.02738916667e-39 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | G1/S DNA Damage Checkpoints |
| REAC:R-HSA-8948751 | 1.0139544864e-38 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Regulation of PTEN stability and activity |
| REAC:R-HSA-68949 | 1.99632281771e-38 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Orc1 removal from chromatin |
| REAC:R-HSA-1234174 | 1.99632281771e-38 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Cellular response to hypoxia |
| REAC:R-HSA-174184 | 2.77737516381e-38 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Cdc20:Phospho-APC/C mediated degradation of Cyclin A |
| REAC:R-HSA-5619084 | 2.77737516381e-38 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | ABC transporter disorders |
| REAC:R-HSA-69017 | 2.77737516381e-38 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | CDK-mediated phosphorylation and removal of Cdc6 |
| GO:0005839 | 3.42101514519e-38 | 0.533333333333 | PSMA6 PSMB2 PSMA8 PSMB8 PSMB9 PSMB6 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSMB10 PSMF1 PSMB5 | proteasome core complex |
| REAC:R-HSA-179419 | 3.84307877231e-38 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint |
| REAC:R-HSA-174178 | 3.84307877231e-38 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| REAC:R-HSA-1168372 | 7.24428210335e-38 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Downstream signaling events of B Cell Receptor (BCR) |
| REAC:R-HSA-176409 | 7.24428210335e-38 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | APC/C:Cdc20 mediated degradation of mitotic proteins |
| REAC:R-HSA-176814 | 9.87209802907e-38 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins |
| REAC:R-HSA-2871837 | 9.87209802907e-38 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | FCERI mediated NF-kB activation |
| REAC:R-HSA-8852276 | 1.33890738655e-37 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | The role of GTSE1 in G2/M progression after G2 checkpoint |
| REAC:R-HSA-5632684 | 1.8075149655e-37 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Hedgehog 'on' state |
| REAC:R-HSA-176408 | 3.25053259484e-37 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Regulation of APC/C activators between G1/S and early anaphase |
| REAC:R-HSA-195253 | 5.74750433506e-37 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Degradation of beta-catenin by the destruction complex |
| REAC:R-HSA-5687128 | 5.74750433506e-37 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | MAPK6/MAPK4 signaling |
| REAC:R-HSA-450531 | 1.00016073795e-36 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Regulation of mRNA stability by proteins that bind AU-rich elements |
| REAC:R-HSA-1236974 | 1.71437331762e-36 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | ER-Phagosome pathway |
| REAC:R-HSA-174143 | 2.23241660843e-36 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | APC/C-mediated degradation of cell cycle proteins |
| REAC:R-HSA-5668541 | 2.23241660843e-36 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | TNFR2 non-canonical NF-kB pathway |
| REAC:R-HSA-453276 | 2.23241660843e-36 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Regulation of mitotic cell cycle |
| GO:1905369 | 4.0827414908e-36 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | endopeptidase complex |
| REAC:R-HSA-202424 | 4.82925626263e-36 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Downstream TCR signaling |
| REAC:R-HSA-69052 | 6.20497417623e-36 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Switching of origins to a post-replicative state |
| REAC:R-HSA-5607764 | 6.20497417623e-36 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | CLEC7A (Dectin-1) signaling |
| REAC:R-HSA-4086400 | 7.94764135661e-36 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | PCP/CE pathway |
| REAC:R-HSA-5689603 | 7.94764135661e-36 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | UCH proteinases |
| REAC:R-HSA-9604323 | 8.54617165612e-36 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | Negative regulation of NOTCH4 signaling |
| REAC:R-HSA-9762114 | 8.54617165612e-36 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2 |
| REAC:R-HSA-382556 | 1.6401947654e-35 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | ABC-family proteins mediated transport |
| REAC:R-HSA-8941858 | 1.93817276372e-35 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | Regulation of RUNX3 expression and activity |
| REAC:R-HSA-983705 | 2.62087143588e-35 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Signaling by the B Cell Receptor (BCR) |
| REAC:R-HSA-1236975 | 4.14274727132e-35 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Antigen processing-Cross presentation |
| REAC:R-HSA-9020702 | 5.18813939146e-35 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Interleukin-1 signaling |
| CORUM:192 | 6.41524571721e-35 | 0.433333333333 | PSMA6 PSMB5 PSMA7 PSMB2 PSMB6 PSME2 PSMB3 PSMB7 PSMA1 PSMB4 PSMA4 PSME1 PSMA5 | PA28-20S proteasome |
| REAC:R-HSA-8878166 | 1.24498363599e-34 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Transcriptional regulation by RUNX2 |
| REAC:R-HSA-9755511 | 1.54039711827e-34 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | KEAP1-NFE2L2 pathway |
| REAC:R-HSA-187577 | 1.84107340944e-34 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | SCF(Skp2)-mediated degradation of p27/p21 |
| REAC:R-HSA-5610787 | 1.90159511757e-34 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Hedgehog 'off' state |
| REAC:R-HSA-202403 | 2.34228874821e-34 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | TCR signaling |
| REAC:R-HSA-174084 | 5.14021960344e-34 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | Autodegradation of Cdh1 by Cdh1:APC/C |
| REAC:R-HSA-2454202 | 6.43411533616e-34 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Fc epsilon receptor (FCERI) signaling |
| REAC:R-HSA-8939236 | 1.39355807733e-33 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | RUNX1 regulates transcription of genes involved in differentiation of HSCs |
| REAC:R-HSA-69239 | 2.93192373783e-33 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Synthesis of DNA |
| REAC:R-HSA-5621481 | 3.51599803396e-33 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | C-type lectin receptors (CLRs) |
| REAC:R-HSA-162909 | 8.51182114261e-33 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Host Interactions of HIV factors |
| GO:1905368 | 9.52695377509e-33 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | peptidase complex |
| REAC:R-HSA-9013694 | 1.08342881534e-32 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | Signaling by NOTCH4 |
| REAC:R-HSA-446652 | 1.68002142185e-32 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Interleukin-1 family signaling |
| REAC:R-HSA-5358351 | 2.34014535279e-32 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Signaling by Hedgehog |
| REAC:R-HSA-9759194 | 4.17157651533e-32 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | Nuclear events mediated by NFE2L2 |
| REAC:R-HSA-6807070 | 4.46751124321e-32 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | PTEN Regulation |
| WP:WP183 | 4.69545628204e-32 | 0.566666666667 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMB3 PSMB7 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMA5 PSMB5 | Proteasome degradation |
| CORUM:194 | 5.20454628935e-32 | 0.4 | PSMA6 PSMA4 PSMB5 PSMA7 PSME3 PSMB2 PSMB3 PSMB7 PSMA1 PSMB4 PSMB6 PSMA5 | PA28gamma-20S proteasome |
| REAC:R-HSA-3858494 | 5.23432864783e-32 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Beta-catenin independent WNT signaling |
| REAC:R-HSA-5619115 | 1.13452203754e-31 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Disorders of transmembrane transporters |
| REAC:R-HSA-69202 | 1.14476246936e-31 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | Cyclin E associated events during G1/S transition |
| REAC:R-HSA-69656 | 1.85753058773e-31 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | Cyclin A:Cdk2-associated events at S phase entry |
| REAC:R-HSA-8878159 | 4.70939568761e-31 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | Transcriptional regulation by RUNX3 |
| REAC:R-HSA-69481 | 1.46511597605e-30 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | G2/M Checkpoints |
| REAC:R-HSA-69242 | 1.46511597605e-30 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | S Phase |
| REAC:R-HSA-9010553 | 3.64669043624e-30 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Regulation of expression of SLITs and ROBOs |
| REAC:R-HSA-109581 | 3.64669043624e-30 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Apoptosis |
| REAC:R-HSA-69306 | 9.84466963271e-30 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | DNA Replication |
| REAC:R-HSA-8951664 | 1.43796971629e-29 | 0.7 | PSMA6 PSMB5 FBXO7 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA8 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Neddylation |
| REAC:R-HSA-5689880 | 1.58849834019e-29 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Ub-specific processing proteases |
| REAC:R-HSA-9711123 | 2.84338503221e-29 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Cellular response to chemical stress |
| REAC:R-HSA-2467813 | 3.18803570403e-29 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Separation of Sister Chromatids |
| CORUM:191 | 4.00037863209e-29 | 0.366666666667 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 PSMB3 PSMB7 PSMA1 PSMB4 PSMB6 PSMA5 | 20S proteasome |
| REAC:R-HSA-69275 | 5.59412266791e-29 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | G2/M Transition |
| REAC:R-HSA-453274 | 6.97430182972e-29 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Mitotic G2-G2/M phases |
| REAC:R-HSA-5357801 | 9.66445335382e-29 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Programmed Cell Death |
| REAC:R-HSA-201681 | 3.7445930675e-28 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | TCF dependent signaling in response to WNT |
| REAC:R-HSA-376176 | 5.05358397714e-28 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Signaling by ROBO receptors |
| REAC:R-HSA-8878171 | 5.57906733928e-28 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Transcriptional regulation by RUNX1 |
| REAC:R-HSA-5673001 | 6.7896053464e-28 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | RAF/MAP kinase cascade |
| REAC:R-HSA-69206 | 9.63848055413e-28 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | G1/S Transition |
| REAC:R-HSA-68867 | 9.63848055413e-28 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | Assembly of the pre-replicative complex |
| REAC:R-HSA-5684996 | 9.99777572069e-28 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | MAPK1/MAPK3 signaling |
| REAC:R-HSA-162906 | 1.46125535411e-27 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | HIV Infection |
| REAC:R-HSA-68882 | 1.76182259409e-27 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Mitotic Anaphase |
| REAC:R-HSA-2555396 | 1.93327134126e-27 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Mitotic Metaphase and Anaphase |
| REAC:R-HSA-983168 | 1.9455864675e-27 | 0.7 | PSMA6 PSMB5 FBXO7 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA8 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Antigen processing: Ubiquitination & Proteasome degradation |
| REAC:R-HSA-1257604 | 3.34475091461e-27 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | PIP3 activates AKT signaling |
| REAC:R-HSA-453279 | 1.00828290509e-26 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | Mitotic G1 phase and G1/S transition |
| REAC:R-HSA-69002 | 1.00828290509e-26 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | DNA Replication Pre-Initiation |
| REAC:R-HSA-5683057 | 1.72700108161e-26 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | MAPK family signaling cascades |
| REAC:R-HSA-5688426 | 1.72700108161e-26 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Deubiquitination |
| CORUM:193 | 3.5982699456e-26 | 0.433333333333 | PSMA6 PSMB5 PSMA7 PSMB2 PSMB6 PSME2 PSMB3 PSMB7 PSMA1 PSMB4 PSMA4 PSME1 PSMA5 | PA700-20S-PA28 complex |
| REAC:R-HSA-9006925 | 6.23305092249e-26 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Intracellular signaling by second messengers |
| REAC:R-HSA-983169 | 1.58608902274e-25 | 0.7 | PSMA6 PSMB5 FBXO7 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA8 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Class I MHC mediated antigen processing & presentation |
| REAC:R-HSA-69620 | 1.79576035299e-25 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Cell Cycle Checkpoints |
| GO:0010498 | 1.92868006178e-25 | 0.766666666667 | PSMB5 PSMA4 PSMA7 PSMA6 PSME3 PSMB2 AKIRIN2 FBXO7 PSMA1 PSMF1 PSMB10 PSMA5 PSMB8 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | proteasomal protein catabolic process |
| REAC:R-HSA-195721 | 6.46963546014e-25 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Signaling by WNT |
| CORUM:181 | 2.99483367359e-24 | 0.366666666667 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 PSMB3 PSMB7 PSMA1 PSMB4 PSMB6 PSMA5 | 26S proteasome |
| REAC:R-HSA-71291 | 3.37420349328e-24 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Metabolism of amino acids and derivatives |
| REAC:R-HSA-157118 | 4.80159933816e-24 | 0.6 | PSMA6 PSMB2 PSMB8 PSME3 PSMB9 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA4 PSMA7 PSME1 PSMB10 PSMF1 PSMB5 | Signaling by NOTCH |
| REAC:R-HSA-5663202 | 6.01900067335e-23 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Diseases of signal transduction by growth factor receptors and second messengers |
| REAC:R-HSA-68886 | 1.4162733487e-22 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | M Phase |
| REAC:R-HSA-449147 | 2.25543992188e-22 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Signaling by Interleukins |
| GO:0051603 | 7.69514435266e-22 | 0.766666666667 | PSMB5 PSMA4 PSMA7 PSMA6 PSME3 PSMB2 AKIRIN2 FBXO7 PSMA1 PSMF1 PSMB10 PSMA5 PSMB8 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | proteolysis involved in protein catabolic process |
| REAC:R-HSA-422475 | 1.18453492932e-20 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Axon guidance |
| REAC:R-HSA-9675108 | 2.47216574014e-20 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Nervous system development |
| REAC:R-HSA-69278 | 6.82578687173e-20 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Cell Cycle, Mitotic |
| GO:0019774 | 8.54288235729e-20 | 0.3 | PSMB8 PSMB2 PSMB6 PSMB7 PSMB4 PSMB9 PSMB10 PSMB3 PSMB5 | proteasome core complex, beta-subunit complex |
| REAC:R-HSA-382551 | 8.89289607388e-20 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Transport of small molecules |
| REAC:R-HSA-1280218 | 1.55414886149e-19 | 0.7 | PSMA6 PSMB5 FBXO7 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA8 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Adaptive Immune System |
| GO:0030163 | 1.7870762957e-19 | 0.766666666667 | PSMB5 PSMA4 PSMA7 PSMA6 PSME3 PSMB2 AKIRIN2 FBXO7 PSMA1 PSMF1 PSMB10 PSMA5 PSMB8 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | protein catabolic process |
| GO:0140535 | 9.55544719623e-19 | 0.766666666667 | PSMB5 PSMA4 PSMA7 PSMG2 PSMA6 PSMG1 PSME3 PSMB2 FBXO7 PSMA1 PSMF1 PSMB10 PSMA5 PSMB8 PSMB6 PSME2 PSMB9 PSME4 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | intracellular protein-containing complex |
| REAC:R-HSA-1280215 | 1.27141765567e-18 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Cytokine Signaling in Immune system |
| REAC:R-HSA-1640170 | 4.23591710439e-18 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Cell Cycle |
| REAC:R-HSA-8953854 | 1.27667713502e-17 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Metabolism of RNA |
| REAC:R-HSA-9824446 | 2.196647443e-17 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Viral Infection Pathways |
| REAC:R-HSA-2262752 | 3.82644231647e-17 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Cellular responses to stress |
| REAC:R-HSA-8953897 | 4.62937891594e-17 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Cellular responses to stimuli |
| GO:0009057 | 2.42746859249e-16 | 0.766666666667 | PSMB5 PSMA4 PSMA7 PSMA6 PSME3 PSMB2 AKIRIN2 FBXO7 PSMA1 PSMF1 PSMB10 PSMA5 PSMB8 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | macromolecule catabolic process |
| GO:0006508 | 2.76340358842e-16 | 0.766666666667 | PSMB5 PSMA4 PSMA7 PSMA6 PSME3 PSMB2 AKIRIN2 FBXO7 PSMA1 PSMF1 PSMB10 PSMA5 PSMB8 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | proteolysis |
| GO:1901565 | 2.88492316202e-16 | 0.766666666667 | PSMB5 PSMA4 PSMA7 PSMA6 PSME3 PSMB2 AKIRIN2 FBXO7 PSMA1 PSMF1 PSMB10 PSMA5 PSMB8 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | organonitrogen compound catabolic process |
| KEGG:05017 | 4.31065944714e-16 | 0.4 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 PSMA8 PSMB7 PSMB3 PSMA1 PSMB4 PSMB6 PSMA5 | Spinocerebellar ataxia |
| REAC:R-HSA-1266738 | 1.01844649427e-15 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Developmental Biology |
| REAC:R-HSA-5663205 | 1.27995887868e-15 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Infectious disease |
| REAC:R-HSA-597592 | 2.01768633249e-15 | 0.733333333333 | PSMB5 PSMA4 PSMA7 PSMA6 PSME3 PSMB2 FBXO7 PSMA1 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 PSMB6 PSME2 PSME4 PSMB9 PSMA8 PSMB7 PSMB4 PSME1 PSMB3 | Post-translational protein modification |
| REAC:R-HSA-168249 | 2.19080636791e-15 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Innate Immune System |
| REAC:R-HSA-212436 | 3.61500652587e-14 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Generic Transcription Pathway |
| REAC:R-HSA-73857 | 3.0509598031e-13 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | RNA Polymerase II Transcription |
| GO:1901575 | 8.02097374943e-13 | 0.766666666667 | PSMB5 PSMA4 PSMA7 PSMA6 PSME3 PSMB2 AKIRIN2 FBXO7 PSMA1 PSMF1 PSMB10 PSMA5 PSMB8 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | organic substance catabolic process |
| KEGG:05012 | 1.11788040901e-12 | 0.4 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 PSMA8 PSMB7 PSMB3 PSMA1 PSMB4 PSMB6 PSMA5 | Parkinson disease |
| KEGG:05020 | 1.58311594827e-12 | 0.4 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 PSMA8 PSMB7 PSMB3 PSMA1 PSMB4 PSMB6 PSMA5 | Prion disease |
| WP:WP5124 | 1.64304839935e-12 | 0.4 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 PSMA8 PSMB7 PSMB3 PSMA1 PSMB4 PSMB6 PSMA5 | Alzheimer 39 s disease |
| WP:WP2059 | 1.64304839935e-12 | 0.4 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 PSMA8 PSMB7 PSMB3 PSMA1 PSMB4 PSMB6 PSMA5 | Alzheimer 39 s disease and miRNA effects |
| REAC:R-HSA-392499 | 2.13527606084e-12 | 0.733333333333 | PSMB5 PSMA4 PSMA7 PSMA6 PSME3 PSMB2 FBXO7 PSMA1 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 PSMB6 PSME2 PSME4 PSMB9 PSMA8 PSMB7 PSMB4 PSME1 PSMB3 | Metabolism of proteins |
| REAC:R-HSA-74160 | 3.43833116487e-12 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Gene expression (Transcription) |
| KEGG:05016 | 5.29279945127e-12 | 0.4 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 PSMA8 PSMB7 PSMB3 PSMA1 PSMB4 PSMB6 PSMA5 | Huntington disease |
| REAC:R-HSA-168256 | 3.14210930038e-11 | 0.7 | PSMA6 PSMB5 FBXO7 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA8 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Immune System |
| KEGG:05014 | 4.4230798861e-11 | 0.4 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 PSMA8 PSMB7 PSMB3 PSMA1 PSMB4 PSMB6 PSMA5 | Amyotrophic lateral sclerosis |
| REAC:R-HSA-1643685 | 4.58996298339e-11 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Disease |
| GO:0019773 | 6.13071804285e-11 | 0.2 | PSMA6 PSMA1 PSMA4 PSMA8 PSMA7 PSMA5 | proteasome core complex, alpha-subunit complex |
| KEGG:05010 | 7.81874833547e-11 | 0.4 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 PSMA8 PSMB7 PSMB3 PSMA1 PSMB4 PSMB6 PSMA5 | Alzheimer disease |
| GO:0009056 | 1.09835992192e-10 | 0.766666666667 | PSMB5 PSMA4 PSMA7 PSMA6 PSME3 PSMB2 AKIRIN2 FBXO7 PSMA1 PSMF1 PSMB10 PSMA5 PSMB8 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | catabolic process |
| GO:1902494 | 6.32858674488e-10 | 0.7 | PSMA6 PSMB5 FBXO7 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMA8 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | catalytic complex |
| KEGG:05022 | 7.89628815762e-10 | 0.4 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 PSMA8 PSMB7 PSMB3 PSMA1 PSMB4 PSMB6 PSMA5 | Pathways of neurodegeneration - multiple diseases |
| GO:1990111 | 1.28317972575e-09 | 0.166666666667 | PSMB10 PSMB8 PSME4 PSMA8 PSMB9 | spermatoproteasome complex |
| REAC:R-HSA-1430728 | 1.30309480582e-09 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Metabolism |
| GO:0043161 | 1.4935867689e-09 | 0.433333333333 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 AKIRIN2 PSMB3 PSMB7 PSMA1 PSMB4 PSMB6 FBXO7 PSMA5 | proteasome-mediated ubiquitin-dependent protein catabolic process |
| GO:0006511 | 8.62947461104e-09 | 0.466666666667 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 AKIRIN2 PSMB3 PSMB7 PSMA1 PSMB4 PSMB6 FBXO7 PSMA5 PSMF1 | ubiquitin-dependent protein catabolic process |
| GO:0019941 | 1.07623165182e-08 | 0.466666666667 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 AKIRIN2 PSMB3 PSMB7 PSMA1 PSMB4 PSMB6 FBXO7 PSMA5 PSMF1 | modification-dependent protein catabolic process |
| GO:0043632 | 1.44938876311e-08 | 0.466666666667 | PSMA6 PSMA4 PSMB5 PSMA7 PSMB2 AKIRIN2 PSMB3 PSMB7 PSMA1 PSMB4 PSMB6 FBXO7 PSMA5 PSMF1 | modification-dependent macromolecule catabolic process |
| REAC:R-HSA-162582 | 1.5653419644e-08 | 0.666666666667 | PSMA6 PSMB5 PSMA8 PSMB8 PSME3 PSMA4 PSMB6 PSME2 PSMA5 PSMB7 PSMB3 PSMA1 PSMB4 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMF1 | Signal Transduction |
| GO:0005654 | 1.19758525124e-06 | 0.833333333333 | PSMB5 PSMA4 PSMA7 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 AKIRIN2 FBXO7 PSMF1 PSMB10 PSMA5 PSMB8 POMP PSME3 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | nucleoplasm |
| GO:0019538 | 5.24340821467e-06 | 0.8 | PSMB5 PSMA4 PSMA7 PSMA6 PSMA1 PSMB2 AKIRIN2 FBXO7 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 PSME3 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | protein metabolic process |
| GO:0031981 | 5.43699481769e-06 | 0.833333333333 | PSMB5 PSMA4 PSMA7 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 AKIRIN2 FBXO7 PSMF1 PSMB10 PSMA5 PSMB8 POMP PSME3 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | nuclear lumen |
| GO:0032991 | 7.11284479346e-06 | 0.9 | PSMB5 PSMA4 PSMA7 PSMG4 AKIRIN1 PSMG2 PSMA6 PSMG1 PSMA1 PSMB2 AKIRIN2 FBXO7 PSMF1 PSMB10 PSME4 PSMB8 PSME3 PSMB6 PSME2 PSMG3 PSMB9 PSMA5 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | protein-containing complex |
| HP:0025131 | 9.49186561461e-05 | 0.1 | PSMB8 PSMB4 PSMB9 | Finger swelling |
| HP:0012490 | 0.000181637880593 | 0.133333333333 | PSMB8 PSMG2 PSMB4 PSMB9 | Panniculitis |
| GO:0005634 | 0.000260943402645 | 0.9 | PSMB5 PSMA4 PSMA7 AKIRIN1 PSMG2 PSMA6 PSMG1 PSMA1 PSMB2 AKIRIN2 FBXO7 PSMF1 PSMB10 PSMA5 PSMB8 POMP PSME3 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | nucleus |
| HP:0033331 | 0.000280549636623 | 0.2 | PSMB8 POMP PSMB9 PSMB4 PSMB10 PSMG2 | Acute phase response |
| GO:1901564 | 0.000440618081946 | 0.8 | PSMB5 PSMA4 PSMA7 PSMA6 PSMA1 PSMB2 AKIRIN2 FBXO7 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 PSME3 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | organonitrogen compound metabolic process |
| CORUM:3034 | 0.000483770340229 | 0.0666666666667 | PSMG1 PSMG2 | PAC1-PAC2 complex |
| CORUM:30 | 0.000483770340229 | 0.0666666666667 | PSME1 PSME2 | PA28 complex |
| CORUM:3033 | 0.000483770340229 | 0.0666666666667 | PSMG3 PSMG4 | PAC3-PAC4 complex |
| HPA:0130201 | 0.000511671716353 | 0.766666666667 | PSMB5 PSMA4 PSMA7 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | colon; endothelial cells[>=Low] |
| GO:0031974 | 0.00077841275817 | 0.833333333333 | PSMB5 PSMA4 PSMA7 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 AKIRIN2 FBXO7 PSMF1 PSMB10 PSMA5 PSMB8 POMP PSME3 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | membrane-enclosed lumen |
| GO:0043233 | 0.00077841275817 | 0.833333333333 | PSMB5 PSMA4 PSMA7 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 AKIRIN2 FBXO7 PSMF1 PSMB10 PSMA5 PSMB8 POMP PSME3 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | organelle lumen |
| GO:0070013 | 0.00077841275817 | 0.833333333333 | PSMB5 PSMA4 PSMA7 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 AKIRIN2 FBXO7 PSMF1 PSMB10 PSMA5 PSMB8 POMP PSME3 PSMB6 PSME2 PSME3IP1 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | intracellular organelle lumen |
| HPA:0480052 | 0.00201956079288 | 0.766666666667 | PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | small intestine; glandular cells[>=Medium] |
| HP:0003565 | 0.0020532068618 | 0.133333333333 | PSMB8 POMP PSMB4 PSMB9 | Elevated erythrocyte sedimentation rate |
| HPA:0150052 | 0.00238576634486 | 0.766666666667 | PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | duodenum; glandular cells[>=Medium] |
| HP:0025021 | 0.00247181977283 | 0.133333333333 | PSMB8 POMP PSMB4 PSMB9 | Abnormal erythrocyte sedimentation rate |
| HP:0009125 | 0.0036035831596 | 0.166666666667 | PSMB8 POMP PSMG2 PSMB4 PSMB9 | Lipodystrophy |
| CORUM:5209 | 0.00481919001511 | 0.0666666666667 | PSMA6 PSMA1 | Ubiquilin-proteasome complex |
| HPA:0460671 | 0.00521684974045 | 0.7 | PSMB8 POMP AKIRIN1 PSMB2 PSMA7 PSME3 PSMB9 PSMB6 PSMF1 PSMG1 PSMA5 PSMB7 PSMB3 PSMA1 RNF181 PSMG3 PSMA4 PSMB10 PSME1 PSME4 PSMB4 | skin 1; melanocytes[>=Low] |
| HPA:0351182 | 0.0094858819063 | 0.566666666667 | PSMA6 POMP AKIRIN1 PSMB5 PSMA7 PSME3 PSMB2 PSMB6 PSMF1 PSMA5 PSMB7 PSMA1 PSMB4 PSMA4 PSME1 PSME4 PSMG1 | pancreas; pancreatic endocrine cells[>=Medium] |
| HPA:0310441 | 0.00957635896773 | 0.733333333333 | PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 | lymph node; non-germinal center cells[>=Low] |
| HPA:0030052 | 0.0101138872209 | 0.7 | PSMA6 POMP AKIRIN1 PSMG1 PSMB8 PSME3 PSMA4 PSMB6 PSMF1 PSMA5 PSMB7 PSMB3 PSMA1 RNF181 PSMB2 PSMA7 PSME1 PSMB10 PSME4 PSMB9 PSMB4 | appendix; glandular cells[>=Medium] |
| HPA:0050000 | 0.0103886135312 | 0.8 | PSMB5 PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSME3 PSMB2 PSMA1 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | breast |
| HPA:0090161 | 0.0108259740334 | 0.7 | PSMA6 POMP AKIRIN1 PSMG1 PSMB8 PSME3 PSMA4 PSMB6 PSMA5 PSMB7 PSMB4 PSMA1 PSMG4 PSMG3 PSMB2 PSMA7 PSME1 PSMB3 PSME4 PSMB9 RNF181 | cerebellum; Purkinje cells[>=Low] |
| HPA:0600221 | 0.0112625088688 | 0.766666666667 | PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | tonsil; squamous epithelial cells[>=Low] |
| HPA:0290402 | 0.0115997197277 | 0.566666666667 | PSMB8 POMP PSMA1 PSMA7 PSME3 PSMA4 PSMB6 PSMF1 PSMA5 PSMB7 PSMB3 RNF181 PSMG3 PSMB2 PSME1 PSME4 PSMB4 | liver; hepatocytes[>=Medium] |
| GO:0005829 | 0.0132920498711 | 0.766666666667 | PSMB5 PSMA4 PSMA7 PSMG2 PSMA6 PSMG1 PSME3 PSMB2 FBXO7 PSMA1 PSMF1 PSMB10 PSMA5 PSMB8 PSMB6 PSME2 PSMB9 PSME4 PSMB7 PSMB3 PSMB4 PSME1 PSMA8 | cytosol |
| HPA:0351181 | 0.0151783005783 | 0.7 | PSMA6 POMP AKIRIN1 PSMB5 PSMB8 PSME3 PSMA4 PSMB6 PSMF1 PSMG1 PSMA5 PSMB7 PSMB4 PSMA1 PSMG4 PSMB2 PSMA7 PSME1 PSMB3 PSME4 RNF181 | pancreas; pancreatic endocrine cells[>=Low] |
| HPA:0160052 | 0.0160535559087 | 0.666666666667 | PSMA6 AKIRIN1 PSMA1 PSMB8 PSME3 PSMA4 PSMB6 PSMF1 PSMA5 PSMB7 PSMB4 PSMB10 PSMG4 PSMB2 PSMA7 PSME1 PSMB3 PSME4 PSMB9 RNF181 | endometrium 1; glandular cells[>=Medium] |
| KEGG:04612 | 0.016468468244 | 0.1 | PSME1 PSME2 PSME3 | Antigen processing and presentation |
| HPA:0050051 | 0.0187784873376 | 0.766666666667 | PSMB5 PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | breast; glandular cells[>=Low] |
| HPA:0291162 | 0.0187873138904 | 0.4 | PSMA6 PSMA1 PSMB8 PSME3 PSMB6 PSMB3 PSMB7 PSMB4 PSMB2 PSMA7 PSME1 PSMA5 | liver; cholangiocytes[>=Medium] |
| HPA:0550052 | 0.019782773033 | 0.733333333333 | PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | stomach 2; glandular cells[>=Medium] |
| HP:0001954 | 0.0203651298838 | 0.133333333333 | PSMB8 PSMG2 PSMB4 PSMB9 | Recurrent fever |
| TF:M09629 | 0.0205675705871 | 0.233333333333 | PSMB8 POMP PSMB9 PSMA4 PSMB10 PSME1 PSMA5 | Factor: IRF-1; motif: NAAANNGAAAGTGAAASTRN |
| HPA:0270362 | 0.0209497859596 | 0.7 | PSMA6 POMP AKIRIN1 PSMB5 PSMB8 PSME3 PSMA4 PSMB6 PSMF1 PSMA5 PSMB7 PSMB4 PSMA1 PSMG4 PSMG3 PSMB2 PSMA7 PSME1 PSMB3 PSME4 RNF181 | kidney; cells in tubules[>=Medium] |
| HPA:0270361 | 0.0236105057813 | 0.766666666667 | PSMB5 PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | kidney; cells in tubules[>=Low] |
| HPA:0530722 | 0.0250967613351 | 0.466666666667 | PSMA6 PSMB2 PSMB8 PSME3 PSMA4 PSMB6 PSMA7 PSMA1 PSMG4 PSMB9 PSMB10 PSME1 PSMA5 RNF181 | spleen; cells in white pulp[>=Medium] |
| HPA:0130051 | 0.0252847066645 | 0.766666666667 | PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | colon; glandular cells[>=Low] |
| GO:0004175 | 0.0264245509181 | 0.233333333333 | PSMB8 PSMB5 PSMA6 PSMB6 PSMB7 PSMB9 PSMB10 | endopeptidase activity |
| TF:M03966_1 | 0.028858437264 | 0.433333333333 | PSMA6 POMP PSMG3 PSME3 PSMA4 PSME2 PSMA8 PSMB7 RNF181 PSMB10 FBXO7 PSME4 PSMF1 | Factor: ELF1; motif: AACCCGGAAGTR; match class: 1 |
| HP:0010702 | 0.0288798515932 | 0.133333333333 | PSMB8 POMP PSMB4 PSMB9 | Increased circulating antibody level |
| HPA:0400051 | 0.0293086460005 | 0.766666666667 | PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | rectum; glandular cells[>=Low] |
| HPA:0470000 | 0.0308059690277 | 0.766666666667 | PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | skin 2 |
| HPA:0480051 | 0.0308962043196 | 0.766666666667 | PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | small intestine; glandular cells[>=Low] |
| HPA:0291161 | 0.0312205729296 | 0.566666666667 | PSMA6 POMP PSMA1 PSMB8 PSME3 PSMA4 PSMB6 PSMA5 PSMB7 PSMB3 RNF181 PSMG3 PSMB2 PSMA7 PSME1 PSMF1 PSMB4 | liver; cholangiocytes[>=Low] |
| HPA:0150051 | 0.0329440425584 | 0.766666666667 | PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | duodenum; glandular cells[>=Low] |
| GO:0070062 | 0.0339893722829 | 0.5 | PSMA6 PSMB2 PSMB8 PSMA4 PSMB6 PSME2 PSMA8 PSMA7 PSMB3 PSMA1 PSMB4 PSMB9 PSME1 PSMA5 PSMB5 | extracellular exosome |
| HPA:0310000 | 0.0345642127626 | 0.733333333333 | PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 | lymph node |
| GO:0016504 | 0.0361255878868 | 0.133333333333 | PSME3 PSME1 PSME4 PSME2 | peptidase activator activity |
| HPA:0600431 | 0.0379709184772 | 0.7 | PSMA6 POMP AKIRIN1 PSMA1 PSMB8 PSME3 PSMA4 PSMB6 PSMF1 PSMA5 PSMB7 PSMB4 PSMB10 PSMG4 PSMB2 PSMA7 PSME1 PSMB3 PSME4 PSMB9 RNF181 | tonsil; germinal center cells[>=Low] |
| GO:1903561 | 0.0383523284654 | 0.5 | PSMA6 PSMB2 PSMB8 PSMA4 PSMB6 PSME2 PSMA8 PSMA7 PSMB3 PSMA1 PSMB4 PSMB9 PSME1 PSMA5 PSMB5 | extracellular vesicle |
| GO:0065010 | 0.0386241796886 | 0.5 | PSMA6 PSMB2 PSMB8 PSMA4 PSMB6 PSME2 PSMA8 PSMA7 PSMB3 PSMA1 PSMB4 PSMB9 PSME1 PSMA5 PSMB5 | extracellular membrane-bounded organelle |
| GO:0043230 | 0.0386241796886 | 0.5 | PSMA6 PSMB2 PSMB8 PSMA4 PSMB6 PSME2 PSMA8 PSMA7 PSMB3 PSMA1 PSMB4 PSMB9 PSME1 PSMA5 PSMB5 | extracellular organelle |
| HPA:0610832 | 0.0398658166928 | 0.7 | PSMA6 POMP PSMB5 PSMB8 PSME3 PSMA4 PSMB6 PSMF1 PSMA5 PSMB7 PSMB4 PSMA1 PSMG4 PSMB2 PSMA7 PSME1 PSMB3 PSMB10 PSME4 PSMB9 RNF181 | urinary bladder; urothelial cells[>=Medium] |
| HPA:0020052 | 0.0402305593848 | 0.7 | PSMA6 POMP PSMB5 PSMB8 PSME3 PSMA4 PSMB6 PSMF1 PSMG1 PSMA5 PSMB7 PSMB4 PSMA1 PSMG4 PSMG3 PSMB2 PSMA7 PSME1 PSMB3 PSME4 RNF181 | adrenal gland; glandular cells[>=Medium] |
| HPA:0320000 | 0.0416091774129 | 0.766666666667 | PSMB5 PSMA4 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | nasopharynx |
| HP:0100614 | 0.0453503809126 | 0.1 | PSMB9 PSMB4 PSMG2 | Myositis |
| HPA:0600432 | 0.0460756134783 | 0.566666666667 | PSMB8 POMP AKIRIN1 PSMB2 PSMA7 PSME3 PSMB9 PSMB6 PSMA5 PSMB7 PSMB3 PSMA1 PSMG4 PSMA4 PSMB10 PSME1 PSME4 | tonsil; germinal center cells[>=Medium] |
| GO:0043248 | 0.0463773280544 | 0.1 | POMP PSMG1 PSMG2 | proteasome assembly |
| GO:0061133 | 0.0463773280544 | 0.1 | PSME1 PSME2 PSME3 | endopeptidase activator activity |
| HPA:0130202 | 0.0468309511 | 0.533333333333 | PSMB8 POMP PSMB5 PSMA7 PSME3 PSMB9 PSMB3 PSMB7 PSMA1 PSMB4 PSMG3 PSMB2 PSMB10 AKIRIN1 PSME4 PSMG1 | colon; endothelial cells[>=Medium] |
| HPA:0090162 | 0.0477281184198 | 0.566666666667 | PSMA6 POMP PSMG1 PSMA7 PSME3 PSMB2 PSMB6 PSMA5 PSMB7 PSMB4 PSMA1 PSMG4 PSMA4 AKIRIN1 PSMB3 PSME4 RNF181 | cerebellum; Purkinje cells[>=Medium] |
| HPA:0600441 | 0.0484831136947 | 0.7 | PSMA6 POMP AKIRIN1 PSMA1 PSMB8 PSME3 PSMA4 PSMB6 PSMF1 PSMA5 PSMB7 PSMB4 PSMB10 PSMG4 PSMB2 PSMA7 PSME1 PSMB3 PSME4 PSMB9 RNF181 | tonsil; non-germinal center cells[>=Low] |
| HPA:0460000 | 0.0491902465228 | 0.766666666667 | PSMA4 PSMA7 PSMG4 AKIRIN1 PSMA6 PSMG1 PSMA1 PSMB2 PSME3 PSMF1 PSMB10 PSMA5 RNF181 PSMB8 POMP PSMB6 PSMG3 PSMB9 PSME4 PSMB7 PSMB4 PSME1 PSMB3 | skin 1 |
| HP:0002716 | 0.0494265057949 | 0.166666666667 | PSMB8 POMP PSMG2 PSMB4 PSMB9 | Lymphadenopathy |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
|---|---|---|---|---|
| PSMB1 | PSMA8 | 1.0 |
structurally_consistent (P49720)
|
|
| PSMA8 | PSMA2 | 1.0 |
mutually_exclusive (Q16401)
|
|
| PSMB6 | PSMA7 | 1.0 | 0.944 | |
| PSMB4 | PSMA8 | 1.0 |
mutually_exclusive (Q16401)
|
|
| PSMB6 | PSMA5 | 1.0 | 0.91 | |
| PSMB2 | PSMA5 | 1.0 | 0.998 | |
| PSMB6 | PSMA2 | 1.0 | 0.906 | |
| PSMA5 | PSMA8 | 1.0 | ||
| PSMA5 | PSMA2 | 1.0 | 0.988 | |
| PSMA6 | PSMB7 | 1.0 | 0.956 |
structurally_consistent (dimer)
|
| PSMB6 | PSMB1 | 1.0 | 0.964 | |
| PSMA3 | PSMA7 | 1.0 | 0.998 |
structurally_consistent (Q99436)
|
| PSMB4 | PSMB5 | 1.0 | 0.588 |
structurally_consistent (dimer)
|
| PSMA3 | PSMA2 | 1.0 | 0.996 |
mutually_exclusive (Q16401)
|
| PSMB2 | PSMB1 | 1.0 | 0.998 | |
| PSMA4 | PSMB1 | 1.0 | 1.0 | |
| PSMB2 | PSMB6 | 1.0 | 0.932 | |
| PSMA3 | PSMA5 | 1.0 | 1.0 | |
| PSMA6 | PSMB4 | 1.0 | 0.978 |
structurally_consistent (dimer)
|
| PSMA6 | PSMA2 | 1.0 | 0.99 | |
| PSMB7 | PSMA2 | 1.0 | 0.92 |
structurally_consistent (dimer)
|
| PSMB4 | PSMA1 | 1.0 | 1.0 |
structurally_consistent (dimer)
|
| PSMB1 | PSMA2 | 1.0 | 0.996 | |
| PSMB6 | PSMB5 | 1.0 | 0.906 |
mutually_exclusive (O75832)
|
| PSMB6 | PSMB4 | 1.0 | 0.79 | |
| PSMA3 | PSMB4 | 1.0 | 0.998 |
structurally_consistent (dimer)
|
| PSMB2 | PSMB4 | 1.0 | 0.988 |
structurally_consistent (dimer)
|
| PSMB2 | PSMA2 | 1.0 | 0.994 | |
| PSMB6 | PSMA1 | 1.0 | 0.936 | |
| PSMB2 | PSMB7 | 1.0 | 0.886 |
structurally_consistent (dimer)
|
| PSMB1 | PSMA5 | 1.0 | 1.0 | |
| PSMB2 | PSMA1 | 1.0 | 1.0 | |
| PSMA1 | PSMA8 | 1.0 | ||
| PSMA3 | PSMA1 | 1.0 | 0.996 | |
| PSMA6 | PSMB5 | 1.0 | 0.506 | |
| PSMA3 | PSMB2 | 1.0 | 1.0 |
structurally_consistent (P28070)
|
| PSMB5 | PSMA5 | 1.0 | 0.672 |
mutually_exclusive (Q16401)
|
| PSMB5 | PSMA1 | 1.0 | 0.708 | |
| PSMB2 | PSMA6 | 1.0 | 0.99 | |
| PSMA3 | PSMB5 | 1.0 | 0.69 |
structurally_consistent (P28070)
|
| PSMA7 | PSMA2 | 1.0 | 0.998 | |
| PSMB7 | PSMB1 | 1.0 | 0.918 |
structurally_consistent (dimer)
|
| PSMA3 | PSMB7 | 1.0 | 0.922 |
structurally_consistent (P28070)
structurally_consistent (dimer) |
| PSMB7 | PSMA5 | 1.0 | 0.926 | |
| PSMA4 | PSMA5 | 1.0 | 0.998 | |
| PSMB2 | PSMA8 | 1.0 | ||
| PSMB5 | PSMB1 | 1.0 | 0.734 | |
| PSMB7 | PSMA8 | 1.0 |
mutually_exclusive (P49720)
|
|
| PSMB7 | PSMB6 | 1.0 | 0.98 |
structurally_consistent (dimer)
|
| PSMA3 | PSMB1 | 1.0 | 0.998 | |
| FBXO7 | PSMF1 | 1.0 | 0.124 | |
| PSMA1 | PSMA2 | 1.0 | 0.998 | |
| PSMB5 | PSMA2 | 1.0 | 0.65 | |
| PSMA6 | PSMA1 | 1.0 | 0.996 | |
| PSMA6 | PSMA5 | 1.0 | 0.996 |
mutually_exclusive (Q16401)
|
| PSMB2 | PSMB5 | 1.0 | 0.506 | |
| PSMA7 | PSMA5 | 1.0 | 1.0 | |
| PSMB7 | PSMA1 | 1.0 | 0.96 |
structurally_consistent (P28070)
|
| PSMA7 | PSMA1 | 1.0 | 0.996 |
mutually_exclusive (Q92530)
|
| PSMA6 | PSMB1 | 1.0 | 0.996 |
structurally_consistent (Q99436)
|
| PSMA6 | PSMA7 | 1.0 | 0.996 | |
| PSMB7 | PSMB4 | 1.0 | 0.842 |
mutually_exclusive (O75832)
structurally_consistent (dimer) |
| PSMA1 | PSMA5 | 1.0 | 1.0 | |
| PSMB7 | PSMA7 | 1.0 | 0.954 |
structurally_consistent (dimer)
|
| PSMB4 | PSMA5 | 1.0 | 0.998 | |
| PSMA4 | PSMA2 | 1.0 | 0.994 |
structurally_consistent (Q99436)
|
| PSMA6 | PSMB6 | 1.0 | 0.902 | |
| PSMA3 | PSMB6 | 1.0 | 0.916 | |
| PSMB1 | PSMA1 | 1.0 | 0.992 | |
| PSMB2 | PSMA7 | 1.0 | 1.0 | |
| PSMA4 | PSMA8 | 1.0 | ||
| PSMB6 | PSMB3 | 1.0 | 0.91 |
mutually_exclusive (O75832)
structurally_consistent (dimer) |
| PSMB5 | PSMA7 | 1.0 | 0.707666666667 | |
| PSMA4 | PSMB4 | 1.0 | 0.998 |
structurally_consistent (dimer)
|
| PSMA3 | PSMA6 | 1.0 | 0.996 |
structurally_consistent (P28070)
|
| PSMA3 | PSMB9 | 1.0 | 0.496 | |
| PSMB7 | PSMB5 | 1.0 | 0.775 |
structurally_consistent (dimer)
|
| PSMB4 | PSMB1 | 1.0 | 0.996 | |
| PSMA4 | PSMB6 | 1.0 | 0.916 | |
| PSME3IP1 | PSME3 | 1.0 | 0.524 | |
| PSMA6 | PSMB9 | 1.0 | 0.4228 | |
| PSMA3 | PSMB3 | 1.0 | 0.998 | |
| PSMA7 | PSMB1 | 1.0 | 0.998 | |
| PSMB2 | PSMB9 | 1.0 | 0.642 | |
| PSMA4 | PSMB9 | 1.0 | 0.452 | |
| PSMB9 | POMP | 1.0 | 0.054 | |
| PSMA3 | PSMA8 | 1.0 |
mutually_exclusive (Q16401)
|
|
| PSMB4 | PSMA7 | 1.0 | 0.996 | |
| PSMB4 | PSMA2 | 1.0 | 0.984 | |
| PSMA6 | PSMB3 | 1.0 | 0.966 | |
| PSMA4 | PSMB7 | 1.0 | 0.95 |
structurally_consistent (P28070)
structurally_consistent (dimer) |
| PSMB9 | PSMA5 | 1.0 | 0.454 | |
| PSMB9 | PSMB5 | 1.0 | 0.395090909091 | |
| PSMB8 | PSMB1 | 1.0 | 0.286 | |
| PSMB2 | FBXO7 | 1.0 | 0.348 | |
| AKIRIN2 | AKIRIN1 | 1.0 | ||
| PSMA4 | PSMB3 | 1.0 | 1.0 |
structurally_consistent (dimer)
|
| PSMB8 | PSMA1 | 1.0 | 0.378 | |
| PSMB2 | PSME4 | 1.0 | 0.174 | |
| PSMA4 | PSMA7 | 1.0 | 0.998 | |
| PSME2 | PSMB3 | 1.0 | 0.69 |
mutually_exclusive (Q92530)
structurally_consistent (dimer) |
| PSMB2 | PSMB3 | 1.0 | 0.988 |
structurally_consistent (P28070)
structurally_consistent (dimer) |
| PSMB8 | PSMA2 | 1.0 | 0.17 | |
| PSMB8 | PSMB2 | 1.0 | 0.476 | |
| PSMA5 | PSMB3 | 1.0 | 0.996 | |
| PSME1 | PSMB3 | 1.0 | 0.546 |
mixed_interface
|
| PSMA4 | PSMA1 | 1.0 | 1.0 |
mutually_exclusive (Q92530)
|
| PSMB9 | PSME3 | 1.0 | 0.264909090909 | |
| PSMB2 | PSMA4 | 1.0 | 0.998 | |
| PSME4 | PSMB7 | 1.0 | 0.202 |
structurally_consistent (dimer)
|
| PSMB5 | PSMA8 | 1.0 | ||
| PSMG1 | PSMA5 | 1.0 | 0.38 | |
| PSMA2 | PSMB3 | 1.0 | 0.988 |
structurally_consistent (Q9UL46)
structurally_consistent (dimer) |
| PSMA3 | PSMA4 | 1.0 | 0.998 |
structurally_consistent (P28070)
|
| PSME4 | PSMB3 | 1.0 | 0.202 |
structurally_consistent (dimer)
|
| PSMB8 | PSMA3 | 1.0 | 0.304 | |
| PSMB7 | FBXO7 | 1.0 | 0.14 | |
| PSMA4 | PSMB5 | 1.0 | 0.744 | |
| PSMB9 | PSMF1 | 1.0 | 0.124 | |
| PSMB8 | PSMA7 | 1.0 | 0.386 |
structurally_consistent (P49720)
|
| PSMB9 | PSME1 | 1.0 | 0.488 | |
| PSMB7 | PSMB3 | 1.0 | 0.77 |
structurally_consistent (dimer)
|
| PSMB9 | PSMB3 | 1.0 | 0.463176470588 |
structurally_consistent (dimer)
|
| PSMB1 | PSMB3 | 1.0 | 0.998 |
structurally_consistent (dimer)
|
| PSMB4 | PSMB3 | 1.0 | 0.986 |
structurally_consistent (dimer)
|
| PSMG1 | PSMB1 | 1.0 | 0.376 | |
| PSMA7 | PSMB3 | 1.0 | 0.998 |
structurally_consistent (dimer)
|
| FBXO7 | PSMB3 | 1.0 | 0.4015 | |
| PSMB6 | PSMA8 | 1.0 | ||
| PSMB6 | FBXO7 | 1.0 | 0.128 | |
| PSME4 | PSMB9 | 1.0 | 0.128 | |
| PSME1 | FBXO7 | 1.0 | 0.14 | |
| PSMA6 | FBXO7 | 1.0 | 0.592 | |
| PSMA6 | PSMA4 | 1.0 | 0.996 | |
| PSME1 | PSME2 | 1.0 | 0.874 |
structurally_consistent (dimer)
|
| PSMG1 | PSMB3 | 1.0 | 0.18 |
structurally_consistent (dimer)
|
| PSMB9 | PSME2 | 1.0 | 0.476 |
structurally_consistent (P49720)
|
| PSME4 | PSMB1 | 1.0 | 0.162 | |
| FBXO7 | PSMA1 | 1.0 | 0.606 | |
| PSMB5 | PSMG1 | 1.0 | 0.178 | |
| PSMB9 | PSMA2 | 1.0 | 0.286 | |
| PSMA1 | PSMB3 | 1.0 | 0.996 |
mutually_exclusive (O75832)
|
| PSMB9 | PSMG4 | 1.0 | 0.142 | |
| POMP | PSMB3 | 1.0 | 0.362 | |
| PSMB9 | PSMG1 | 1.0 | 0.148 |
mutually_exclusive (P28070)
|
| PSMB2 | PSMG1 | 0.999 | 0.262 | |
| PSMB4 | FBXO7 | 0.999 | 0.246 | |
| PSMG4 | PSMA1 | 0.999 | 0.156 |
structurally_consistent (Q9BT73)
structurally_consistent (dimer) |
| PSMG1 | PSMG2 | 0.999 | 0.958 |
structurally_consistent (P49720)
|
| PSMB8 | PSMB6 | 0.999 | 0.464 | |
| PSME2 | PSMG2 | 0.999 | 0.048 | |
| PSMG4 | PSMG2 | 0.999 | 0.192 |
structurally_consistent (dimer)
|
| PSMB2 | PSMF1 | 0.999 | 0.334 | |
| PSMB9 | PSMA7 | 0.999 | 0.576 | |
| PSME2 | PSMG1 | 0.999 | 0.134 |
mutually_exclusive (P49720)
|
| PSMB1 | POMP | 0.999 | 0.472 | |
| PSMB9 | PSMG3 | 0.999 | 0.052 | |
| PSMB5 | FBXO7 | 0.999 | 0.074 | |
| PSMB5 | PSMB3 | 0.999 | 0.51 |
structurally_consistent (dimer)
|
| PSMB9 | PSMA8 | 0.999 | ||
| PSMF1 | PSMB3 | 0.999 | 0.414 |
structurally_consistent (dimer)
|
| PSME1 | PSMA2 | 0.999 | 0.69 |
structurally_consistent (O00231)
|
| PSMB7 | PSMB9 | 0.999 | 0.546 |
structurally_consistent (dimer)
|
| PSMA3 | PSME2 | 0.999 | 0.758 | |
| FBXO7 | PSMA5 | 0.999 | 0.396511210762 | |
| PSME4 | PSMA7 | 0.999 | 0.256 | |
| PSMA6 | PSMF1 | 0.999 | 0.636 | |
| PSMB6 | PSMG1 | 0.999 | 0.136 | |
| PSMG1 | FBXO7 | 0.999 | 0.096 | |
| PSMA6 | PSMA8 | 0.999 | ||
| PSME4 | PSMA2 | 0.999 | 0.16 | |
| PSMA4 | PSME1 | 0.999 | 0.678 | |
| PSMG2 | PSMF1 | 0.999 | 0.046 |
structurally_consistent (P49720)
|
| PSMG2 | PSMB1 | 0.999 | 0.142 | |
| PSME2 | FBXO7 | 0.999 | 0.16 | |
| PSME4 | PSMB5 | 0.999 | 0.136 | |
| PSMA8 | PSMB3 | 0.999 |
mutually_exclusive (Q16401)
structurally_consistent (dimer) |
|
| PSME4 | PSMB4 | 0.999 | 0.158 | |
| PSME1 | PSMB4 | 0.999 | 0.622 | |
| PSMB4 | PSME3 | 0.999 | 0.114 | |
| PSMB8 | PSMB4 | 0.999 | 0.284 |
mutually_exclusive (Q99436)
structurally_consistent (dimer) |
| PSMG2 | PSMG3 | 0.999 | 0.114 |
structurally_consistent (Q5JS54)
|
| PSMB7 | PSME1 | 0.999 | 0.214 |
mutually_exclusive (O75832)
|
| PSMG4 | PSMA2 | 0.999 | 0.128 |
structurally_consistent (dimer)
|
| PSMG2 | FBXO7 | 0.999 | 0.11 | |
| PSMB8 | PSMA5 | 0.999 | 0.276 | |
| PSMB1 | FBXO7 | 0.999 | 0.49 | |
| PSMB8 | PSMA4 | 0.999 | 0.236 | |
| PSMB2 | PSME1 | 0.999 | 0.604 | |
| PSMB10 | PSMB3 | 0.999 | 0.6 |
structurally_consistent (P28070)
structurally_consistent (dimer) |
| PSMB5 | PSMF1 | 0.999 | 0.214 | |
| PSMB7 | POMP | 0.999 | 0.194 |
structurally_consistent (dimer)
|
| PSMB1 | PSMF1 | 0.999 | 0.506 | |
| FBXO7 | PSMA2 | 0.999 | 0.388 | |
| PSMB7 | PSMF1 | 0.999 | 0.174 |
structurally_consistent (dimer)
|
| PSMB8 | PSMB7 | 0.999 | 0.254 |
structurally_consistent (dimer)
|
| PSMB7 | PSMG1 | 0.999 | 0.154 | |
| PSMG4 | PSMA5 | 0.999 | 0.204 |
structurally_consistent (Q9BT73)
|
| PSMA3 | FBXO7 | 0.999 | 0.606 | |
| PSMB9 | PSMA1 | 0.999 | 0.508 | |
| PSMA3 | PSME1 | 0.999 | 0.672 | |
| PSMF1 | PSMA5 | 0.999 | 0.62 | |
| PSME1 | PSMG1 | 0.999 | 0.1 | |
| PSME2 | PSMF1 | 0.999 | 0.096 |
mutually_exclusive (P49720)
structurally_consistent (dimer) |
| POMP | PSMA5 | 0.999 | 0.516 | |
| PSME1 | PSMA7 | 0.999 | 0.63 | |
| PSMB9 | PSMB10 | 0.999 | 0.658 | |
| PSMB2 | PSMG2 | 0.999 | 0.102 | |
| PSMG2 | PSMB3 | 0.999 | 0.068 |
structurally_consistent (dimer)
|
| PSME2 | PSMB5 | 0.999 | 0.186 | |
| PSME4 | PSMF1 | 0.999 | 0.164 | |
| PSMG3 | PSMA5 | 0.999 | 0.565 |
structurally_consistent (dimer)
|
| PSMA7 | FBXO7 | 0.999 | 0.514 | |
| PSMG3 | PSMA1 | 0.999 | 0.3656 |
structurally_consistent (Q5JS54)
structurally_consistent (dimer) |
| PSMA3 | PSMF1 | 0.999 | 0.658 | |
| PSME4 | PSME2 | 0.999 | 0.136 | |
| PSME4 | PSMG2 | 0.999 | 0.172 | |
| PSMA4 | PSME2 | 0.999 | 0.638 |
structurally_consistent (P49720)
|
| PSMB2 | PSME2 | 0.999 | 0.722 |
structurally_consistent (dimer)
|
| PSME2 | PSMA5 | 0.999 | 0.694 | |
| PSMB7 | PSME3 | 0.999 | 0.334 | |
| PSMG1 | PSMF1 | 0.999 | 0.096 |
mutually_exclusive (P49720)
|
| PSMB6 | PSMG2 | 0.999 | 0.096 | |
| PSMA4 | PSMF1 | 0.999 | 0.56 |
structurally_consistent (O00231)
structurally_consistent (dimer) |
| PSMF1 | PSMA2 | 0.999 | 0.512 | |
| PSME4 | PSME1 | 0.999 | 0.11427027027 | |
| PSME1 | PSMA5 | 0.999 | 0.634 |
structurally_consistent (dimer)
|
| PSMB4 | PSMG1 | 0.999 | 0.16 |
structurally_consistent (dimer)
|
| PSME4 | PSMG1 | 0.999 | 0.222 | |
| PSME4 | PSMA5 | 0.999 | 0.192 | |
| PSMB2 | POMP | 0.999 | 0.272 |
structurally_consistent (Q99436)
|
| PSME4 | PSMA1 | 0.998 | 0.2 | |
| PSME2 | PSMA2 | 0.998 | 0.708 |
mutually_exclusive (Q9Y5K5)
structurally_consistent (dimer) |
| PSMA6 | PSME2 | 0.998 | 0.732 | |
| PSMA4 | FBXO7 | 0.998 | 0.392 | |
| PSME4 | PSMA4 | 0.998 | 0.174 | |
| PSME1 | PSMB1 | 0.998 | 0.796 | |
| PSMA6 | PSMG2 | 0.998 | 0.126 | |
| PSME1 | PSMG2 | 0.998 | 0.0582702702703 |
structurally_consistent (dimer)
|
| PSMB9 | PSME3IP1 | 0.998 | 0.088 | |
| PSMB9 | PSMB1 | 0.998 | 0.432 | |
| PSMA7 | PSMG2 | 0.998 | 0.176 | |
| PSMB7 | PSMG3 | 0.998 | 0.094 |
structurally_consistent (dimer)
|
| PSMG3 | PSMB3 | 0.998 | 0.262 |
structurally_consistent (Q99436)
|
| PSMG1 | PSMA7 | 0.998 | 0.258 | |
| PSMB4 | POMP | 0.998 | 0.198 | |
| PSMF1 | PSMA1 | 0.998 | 0.742 |
structurally_consistent (dimer)
|
| PSME1 | PSMB6 | 0.998 | 0.32425 |
mutually_exclusive (O75832)
|
| PSME3 | PSMB3 | 0.998 | 0.324 | |
| PSMB9 | PSMG2 | 0.998 | 0.186 | |
| PSMA1 | PSME3IP1 | 0.998 | 0.245 | |
| PSME2 | PSMB6 | 0.998 | 0.547166666667 |
structurally_consistent (P49720)
|
| PSMA1 | PSME3 | 0.998 | 0.45 |
structurally_consistent (Q9UL46)
|
| PSMB4 | PSMF1 | 0.998 | 0.316 |
mutually_exclusive (P49720)
|
| PSME2 | PSMA1 | 0.998 | 0.624 |
structurally_consistent (dimer)
|
| PSME2 | PSMB4 | 0.998 | 0.514 | |
| PSMB5 | PSMG2 | 0.998 | 0.17 | |
| PSME1 | PSMB5 | 0.998 | 0.264 | |
| PSMG2 | PSMA8 | 0.998 | ||
| PSME2 | PSMB1 | 0.998 | 0.736 | |
| PSME1 | PSMF1 | 0.998 | 0.198 | |
| PSMG4 | PSMB3 | 0.998 | 0.114 |
mutually_exclusive (Q969U7)
|
| PSMA7 | PSMA8 | 0.998 | ||
| PSMA4 | PSME3 | 0.998 | 0.392 | |
| PSME2 | PSMA7 | 0.998 | 0.67 | |
| PSMA2 | PSME3 | 0.998 | 0.358 | |
| PSMG2 | POMP | 0.998 | 0.044 | |
| PSMA6 | PSME1 | 0.997 | 0.666 | |
| PSME4 | PSMA6 | 0.997 | 0.204 | |
| PSMB7 | PSMG4 | 0.997 | 0.082 |
structurally_consistent (dimer)
|
| PSMA4 | PSMG1 | 0.997 | 0.246 | |
| PSME1 | PSME3 | 0.997 | 0.365111111111 |
mutually_exclusive (Q9UL46)
structurally_consistent (dimer) |
| PSMA6 | PSMG1 | 0.997 | 0.392 | |
| PSME2 | PSME3 | 0.997 | 0.126 |
mutually_exclusive (Q06323)
structurally_consistent (dimer) |
| PSMA3 | PSME3 | 0.997 | 0.418 | |
| PSMA3 | PSMG1 | 0.997 | 0.42 | |
| POMP | PSMA2 | 0.997 | 0.33 | |
| PSMG1 | PSMA2 | 0.997 | 0.254 | |
| PSMG3 | PSMA2 | 0.997 | 0.222 |
structurally_consistent (Q5JS54)
|
| PSMG4 | PSMA7 | 0.997 | 0.132 |
structurally_consistent (dimer)
|
| PSMB7 | PSME2 | 0.997 | 0.352 | |
| PSMB9 | PSMB4 | 0.997 | 0.485428571429 |
structurally_consistent (dimer)
|
| PSMB2 | PSME3 | 0.997 | 0.29 | |
| PSMB8 | PSMA6 | 0.997 | 0.29 | |
| PSMA7 | PSMF1 | 0.996 | 0.752 |
structurally_consistent (dimer)
|
| PSME3IP1 | PSMB3 | 0.996 | 0.152 | |
| PSMB6 | PSME3 | 0.996 | 0.582 | |
| PSMA7 | PSMG3 | 0.996 | 0.396 |
structurally_consistent (Q5JS54)
|
| PSMB1 | PSME3 | 0.996 | 0.44 | |
| PSME1 | PSMA1 | 0.996 | 0.67 | |
| PSMF1 | PSME3 | 0.996 | 0.094 | |
| PSMG2 | PSME3 | 0.996 | 0.18 | |
| PSMG1 | POMP | 0.996 | 0.064 | |
| PSMB9 | PSMB6 | 0.996 | 0.59 | |
| POMP | PSMA8 | 0.995 | ||
| PSME4 | POMP | 0.995 | 0.038 | |
| PSME2 | POMP | 0.995 | 0.066 |
structurally_consistent (Q15008)
|
| POMP | PSMF1 | 0.995 | 0.052 | |
| PSMB5 | POMP | 0.995 | 0.118 | |
| PSMF1 | PSMA8 | 0.995 |
structurally_consistent (O00231)
|
|
| PSME2 | PSMA8 | 0.995 |
structurally_consistent (P49720)
|
|
| PSMB9 | FBXO7 | 0.995 | 0.06 | |
| PSME4 | FBXO7 | 0.995 | 0.092 | |
| AKIRIN2 | PSMA2 | 0.995 | 0.447 | |
| PSMA3 | PSME4 | 0.995 | 0.228 | |
| PSMA6 | PSME3 | 0.995 | 0.602 | |
| PSMB4 | PSMG2 | 0.995 | 0.11 | |
| PSMB5 | PSME3 | 0.995 | 0.412 | |
| PSMA7 | PSME3 | 0.995 | 0.446 | |
| PSMB6 | PSMF1 | 0.995 | 0.246 | |
| PSMG1 | PSMA1 | 0.995 | 0.29575 | |
| PSMA3 | PSMG2 | 0.995 | 0.116 | |
| PSME4 | PSMB6 | 0.995 | 0.206 | |
| PSMA7 | POMP | 0.994 | 0.512 | |
| PSMG2 | PSMA2 | 0.994 | 0.098 | |
| PSMA4 | POMP | 0.994 | 0.478666666667 | |
| PSMB1 | PSME3IP1 | 0.994 | 0.228 | |
| PSMG2 | PSMA5 | 0.994 | 0.154 | |
| PSME1 | POMP | 0.994 | 0.096 | |
| PSMB6 | POMP | 0.994 | 0.196 | |
| PSMB2 | PSMG4 | 0.994 | 0.11 |
mutually_exclusive (Q99436)
|
| PSME1 | PSMA8 | 0.993 | ||
| AKIRIN2 | PSMB3 | 0.993 | 0.45 | |
| PSMB7 | PSMG2 | 0.993 | 0.1 | |
| PSMA3 | POMP | 0.993 | 0.554 | |
| POMP | FBXO7 | 0.993 | 0.052 | |
| PSMB7 | PSME3IP1 | 0.993 | 0.144 |
structurally_consistent (dimer)
|
| PSME4 | PSMA8 | 0.993 | ||
| PSMG1 | PSMA8 | 0.993 | ||
| PSME2 | PSME3IP1 | 0.993 | 0.096 | |
| PSMG4 | PSME3 | 0.992 | 0.058 | |
| PSMA6 | POMP | 0.992 | 0.472 | |
| FBXO7 | PSMA8 | 0.992 | ||
| AKIRIN2 | PSMB4 | 0.992 | 0.44 | |
| PSMA5 | PSME3 | 0.992 | 0.42 | |
| FBXO7 | PSME3 | 0.992 | 0.138 | |
| POMP | PSMA1 | 0.992 | 0.544 | |
| PSMG4 | PSMG1 | 0.992 | 0.176 | |
| PSMG2 | PSMA1 | 0.992 | 0.144 | |
| PSMA5 | PSMB10 | 0.992 | 0.657636363636 | |
| PSMB10 | PSMA2 | 0.991 | 0.464 | |
| PSME4 | PSME3 | 0.991 | 0.14 | |
| PSMG1 | PSMG3 | 0.991 | 0.178 | |
| PSMA8 | PSME3 | 0.991 | ||
| PSMA6 | PSMG3 | 0.99 | 0.272 | |
| PSMG4 | PSMF1 | 0.99 | 0.03 | |
| PSMG3 | PSMF1 | 0.989 | 0.072 | |
| PSMB7 | AKIRIN1 | 0.989 | ||
| PSMA1 | PSMB10 | 0.989 | 0.702 |
structurally_consistent (P28070)
|
| PSMB4 | PSMB10 | 0.988 | 0.392 |
structurally_consistent (dimer)
|
| PSMG3 | POMP | 0.988 | 0.048 | |
| PSMG2 | PSME3IP1 | 0.987 | 0.15 | |
| PSMA6 | PSMG4 | 0.987 | 0.218 | |
| PSMB2 | PSMG3 | 0.987 | 0.242 | |
| PSME1 | PSME3IP1 | 0.987 | 0.0442702702703 | |
| PSMG4 | PSME1 | 0.987 | 0.11 | |
| PSMB6 | PSME3IP1 | 0.986 | 0.16 |
structurally_consistent (Q99436)
|
| PSMG1 | PSME3 | 0.986 | 0.264 | |
| PSMF1 | PSME3IP1 | 0.986 | 0.096 |
structurally_consistent (Q99436)
|
| PSMG3 | PSMB1 | 0.986 | 0.282 | |
| POMP | PSME3 | 0.986 | 0.106 | |
| PSMB2 | AKIRIN2 | 0.985 | 0.6 | |
| PSMB8 | PSMB5 | 0.985 | 0.413466666667 |
mutually_exclusive (P28070)
|
| PSMB4 | PSME3IP1 | 0.985 | 0.146 | |
| PSMG1 | PSME3IP1 | 0.984 | 0.146 | |
| AKIRIN2 | PSMB5 | 0.984 | 0.402 | |
| PSMA4 | PSMG3 | 0.983 | 0.382 | |
| POMP | PSME3IP1 | 0.981 | 0.064 | |
| PSMA4 | PSMG4 | 0.981 | 0.21 | |
| PSMB9 | AKIRIN1 | 0.98 | ||
| PSMB8 | PSMB3 | 0.98 | 0.24 |
structurally_consistent (dimer)
|
| AKIRIN2 | PSMB9 | 0.98 | 0.174 | |
| AKIRIN1 | PSMA2 | 0.979 | ||
| PSME3IP1 | PSMA2 | 0.978 | 0.19 | |
| AKIRIN2 | PSMG1 | 0.977 | 0.212 | |
| PSMG4 | PSMB4 | 0.977 | 0.116 | |
| PSMG4 | PSMB6 | 0.975 | 0.054 | |
| AKIRIN2 | PSMG2 | 0.975 | 0.18 | |
| PSMG3 | PSME3 | 0.975 | 0.116 | |
| PSMB9 | RNF181 | 0.974 | 0.046 | |
| PSMG4 | PSMB1 | 0.974 | 0.218 | |
| RNF181 | PSMB3 | 0.974 | 0.256 | |
| AKIRIN2 | PSME2 | 0.974 | 0.168 | |
| PSME4 | PSME3IP1 | 0.973 | 0.032 | |
| AKIRIN2 | PSME1 | 0.973 | 0.208923076923 | |
| PSMG4 | PSME3IP1 | 0.972 | 0.028 |
structurally_consistent (Q99436)
|
| PSMG4 | PSME2 | 0.971 | 0.072 | |
| PSMG4 | PSMA8 | 0.97 | ||
| PSMG4 | POMP | 0.97 | 0.022 | |
| PSMG4 | FBXO7 | 0.97 | 0.034 | |
| PSMB8 | PSMB10 | 0.97 | 0.314 |
structurally_consistent (P28070)
|
| PSME1 | PSMG3 | 0.969 | 0.082 | |
| AKIRIN2 | PSME3 | 0.968 | 0.2615 | |
| PSMA4 | PSME3IP1 | 0.968 | 0.344 | |
| AKIRIN2 | PSMA6 | 0.967 | 0.826703828829 | |
| PSME4 | PSMG4 | 0.967 | 0.062 | |
| AKIRIN2 | PSMB7 | 0.967 | 0.247236008573 | |
| AKIRIN1 | PSMA5 | 0.966 | ||
| PSMA4 | PSMG2 | 0.966 | 0.138 | |
| PSMG4 | PSMG3 | 0.965 | 0.792 |
structurally_consistent (Q99436)
structurally_consistent (dimer) |
| PSME2 | PSMG3 | 0.961 | 0.11 | |
| PSMB8 | PSME2 | 0.961 | 0.342 | |
| PSMG4 | PSMB5 | 0.96 | 0.064 | |
| PSMA8 | PSMB10 | 0.959 | ||
| PSME2 | PSMB10 | 0.959 | 0.535277777778 | |
| AKIRIN2 | PSMB6 | 0.958 | 0.368 | |
| PSMB5 | PSME3IP1 | 0.958 | 0.106 | |
| PSME4 | PSMB10 | 0.957 | 0.2048 | |
| PSMB7 | PSMB10 | 0.957 | 0.36 | |
| PSMA6 | PSME3IP1 | 0.956 | 0.226 |
structurally_consistent (Q99436)
|
| POMP | PSMB10 | 0.955 | 0.114 | |
| PSMB5 | PSMG3 | 0.954 | 0.11 |
structurally_consistent (Q99436)
|
| PSMA8 | PSME3IP1 | 0.953 | ||
| PSMG2 | PSMB10 | 0.953 | 0.09 |
mutually_exclusive (P49720)
|
| PSMA3 | PSMG4 | 0.953 | 0.204 |
structurally_consistent (Q99436)
|
| PSMF1 | PSMB10 | 0.952 | 0.17 |
mutually_exclusive (P49720)
|
| PSMG1 | PSMB10 | 0.952 | 0.176 |
mutually_exclusive (P49720)
|
| PSMA6 | PSMB10 | 0.951 | 0.594 | |
| PSMA3 | PSMB10 | 0.95 | 0.608 | |
| PSMA7 | PSMB10 | 0.95 | 0.627428571429 |
mutually_exclusive (P54578)
|
| PSMB2 | PSMB10 | 0.95 | 0.637336390436 | |
| PSMB5 | PSMB10 | 0.95 | 0.33 |
mutually_exclusive (P49720)
|
| PSMB1 | PSMB10 | 0.95 | 0.621636363636 | |
| PSMB6 | PSMG3 | 0.949 | 0.07 |
structurally_consistent (Q99436)
|
| PSMA4 | PSMB10 | 0.948 | 0.552 |
structurally_consistent (P28070)
|
| PSMB2 | PSME3IP1 | 0.947 | 0.206 | |
| PSMG3 | PSME3IP1 | 0.946 | 0.084 | |
| PSMB4 | PSMG3 | 0.945 | 0.046 |
structurally_consistent (Q99436)
|
| PSMG3 | PSMA8 | 0.945 | ||
| AKIRIN2 | FBXO7 | 0.945 | 0.132 | |
| PSMA5 | PSME3IP1 | 0.943 | 0.178 | |
| PSME1 | PSMB10 | 0.942 | 0.560333333333 | |
| PSMB8 | PSME4 | 0.94 | 0.06 | |
| PSMB10 | PSME3 | 0.935 | 0.39592 | |
| PSME4 | PSMG3 | 0.93 | 0.074 | |
| PSMB8 | PSMG2 | 0.926 | 0.066 |
mutually_exclusive (P49720)
|
| FBXO7 | PSMB10 | 0.922 | 0.11 | |
| AKIRIN2 | PSMA5 | 0.915 | 0.828 | |
| AKIRIN2 | PSMA4 | 0.915 | 0.659466666667 | |
| PSMG3 | PSMB10 | 0.91 | 0.106 | |
| RNF181 | FBXO7 | 0.896 | 0.066 | |
| PSMA3 | AKIRIN2 | 0.896 | 0.807466666667 | |
| PSMA7 | PSME3IP1 | 0.894 | 0.194 | |
| PSMB8 | PSMB9 | 0.891 | 0.478 |
structurally_consistent (Q99436)
|
| PSME4 | AKIRIN2 | 0.885 | 0.172 | |
| AKIRIN1 | PSMB3 | 0.883 | ||
| AKIRIN2 | PSMA7 | 0.882 | 0.669875 | |
| PSMG4 | PSMB10 | 0.881 | 0.224491361146 | |
| RNF181 | PSMB1 | 0.876 | 0.152 | |
| PSME3IP1 | PSMB10 | 0.873 | 0.09 | |
| AKIRIN2 | PSMA1 | 0.868 | 0.732 | |
| PSMB6 | PSMB10 | 0.859 | 0.242 |
mutually_exclusive (P49720)
structurally_consistent (dimer) |
| AKIRIN2 | RNF181 | 0.858 | 0.154 | |
| AKIRIN2 | PSMB10 | 0.855 | 0.354 | |
| AKIRIN2 | PSMF1 | 0.851 | 0.092 | |
| AKIRIN1 | PSMA1 | 0.85 | ||
| PSMA3 | AKIRIN1 | 0.85 | ||
| PSMA3 | PSMG3 | 0.849 | 0.312 | |
| PSMB2 | AKIRIN1 | 0.845 | ||
| AKIRIN2 | POMP | 0.842 | 0.088 | |
| RNF181 | AKIRIN1 | 0.835 | ||
| AKIRIN1 | PSMB1 | 0.834 | ||
| AKIRIN2 | PSMG3 | 0.824 | 0.074 | |
| PSMB5 | AKIRIN1 | 0.823 | ||
| PSMB8 | PSME1 | 0.822 | 0.382 |
structurally_consistent (P49720)
|
| AKIRIN1 | PSMB10 | 0.815 | ||
| RNF181 | PSMA7 | 0.814 | 0.166 | |
| AKIRIN2 | PSMA8 | 0.796 | ||
| PSMA6 | AKIRIN1 | 0.792 | ||
| PSME4 | AKIRIN1 | 0.792 | ||
| PSME2 | AKIRIN1 | 0.792 | ||
| AKIRIN1 | PSMG1 | 0.785 | ||
| PSMA4 | AKIRIN1 | 0.785 | ||
| AKIRIN1 | PSMF1 | 0.785 | ||
| PSMB4 | AKIRIN1 | 0.785 | ||
| AKIRIN1 | POMP | 0.785 | ||
| PSMB6 | AKIRIN1 | 0.785 | ||
| AKIRIN1 | PSMA8 | 0.784 | ||
| AKIRIN1 | PSMA7 | 0.782 | ||
| AKIRIN1 | PSMG2 | 0.78 | ||
| PSME1 | AKIRIN1 | 0.776 | ||
| PSMG4 | AKIRIN1 | 0.773 | ||
| PSMB7 | RNF181 | 0.757 | 0.164 | |
| AKIRIN2 | PSMG4 | 0.752 | 0.1 | |
| AKIRIN2 | PSMB1 | 0.749 | 0.716 | |
| PSMG3 | FBXO7 | 0.741 | 0.088 | |
| AKIRIN1 | FBXO7 | 0.738 | ||
| RNF181 | PSMA1 | 0.737 | 0.138222222222 | |
| AKIRIN1 | PSME3IP1 | 0.73 | ||
| PSMA3 | PSME3IP1 | 0.725 | 0.29 | |
| AKIRIN1 | PSMG3 | 0.715 | ||
| PSMB8 | PSMG1 | 0.666 | 0.088 |
structurally_consistent (P49720)
|
| PSMA4 | RNF181 | 0.654 | 0.156 | |
| FBXO7 | PSME3IP1 | 0.615 | 0.056 | |
| AKIRIN1 | PSME3 | 0.613 | ||
| RNF181 | PSMB5 | 0.595 | 0.12 | |
| RNF181 | PSMB4 | 0.569 | 0.166 | |
| PSMA6 | RNF181 | 0.546 | 0.185368421053 | |
| PSMB2 | RNF181 | 0.488 | 0.264 | |
| RNF181 | PSMB6 | 0.464 | 0.208628571429 | |
| PSMA3 | RNF181 | 0.408 | 0.173368421053 | |
| RNF181 | PSMA5 | 0.401 | 0.172 | |
| AKIRIN2 | PSME3IP1 | 0.364 | 0.126 | |
| PSMB8 | AKIRIN2 | 0.356 | 0.222505494505 | |
| PSMB8 | AKIRIN1 | 0.334 | ||
| PSME1 | RNF181 | 0.3 | 0.15 | |
| RNF181 | PSMA2 | 0.275 | 0.168 | |
| RNF181 | PSMA8 | 0.252 | ||
| PSME4 | RNF181 | 0.252 | 0.122 | |
| PSMB8 | POMP | 0.2 | 0.064 |
structurally_consistent (Q99436)
|
| RNF181 | PSMB10 | 0.199 | 0.08 | |
| PSME2 | RNF181 | 0.191 | 0.16 | |
| RNF181 | PSMG3 | 0.191 | 0.04 | |
| PSMB8 | PSMA8 | 0.188 |
structurally_consistent (P49720)
|
|
| PSMG4 | RNF181 | 0.184 | 0.109333333333 | |
| RNF181 | POMP | 0.176 | 0.078 | |
| RNF181 | PSMG1 | 0.176 | 0.116 | |
| RNF181 | PSMF1 | 0.139 | 0.132 | |
| RNF181 | PSME3 | 0.103 | 0.17 | |
| PSMB8 | PSMF1 | 0.099 | 0.072 | |
| RNF181 | PSMG2 | 0.097 | 0.168 | |
| RNF181 | PSME3IP1 | 0.088 | 0.128 | |
| PSMB8 | PSME3 | 0.083 | 0.18 | |
| PSMB8 | PSMG4 | 0.074 | 0.064 | |
| PSMB8 | FBXO7 | 0.074 | 0.066 | |
| PSMB8 | PSMG3 | 0.074 | 0.056 |
structurally_consistent (Q99436)
|
| PSMB8 | PSME3IP1 | 0.044 | 0.046 |
structurally_consistent (Q99436)
|
| PSMB8 | RNF181 | 0.026 | 0.076 |
Related Complexes