hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00357.1
Complex Portal: CPX-12772
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ATG2A | Autophagy-related protein 2 homolog A | 5 | UniProt NCBI |
| WDR45 | WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45) | 5 | UniProt NCBI |
| UBTD1 | Ubiquitin domain-containing protein 1 | 5 | UniProt NCBI |
| RFTN1 | Raftlin (Cell migration-inducing gene 2 protein) (Raft-linking protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4577 | 0.00198508114189 | 0.5 | ATG2A WDR45 | Neurodegeneration with brain iron accumulation NBIA subtypes pathway |
| KEGG:04140 | 0.0298999303213 | 0.5 | ATG2A WDR45 | Autophagy - animal |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ATG2A | WDR45 | 0.991 | 0.12 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_WMM hein () |
| ATG2A | RFTN1 | 0.988 | 0.038 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| ATG2A | UBTD1 | 0.974 | 0.066 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| WDR45 | UBTD1 | 0.408 | 0.09 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes