hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00373.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CWC22 | Pre-mRNA-splicing factor CWC22 homolog (Nucampholin homolog) (fSAPb) | 5 | UniProt NCBI |
| EPB41L2 | Band 4.1-like protein 2 (Erythrocyte membrane protein band 4.1-like 2) (Generally expressed protein 4.1) (4.1G) | 5 | UniProt NCBI |
| ACIN1 | Apoptotic chromatin condensation inducer in the nucleus (Acinus) | 5 | UniProt NCBI |
| RNPS1 | RNA-binding protein with serine-rich domain 1 (SR-related protein LDC2) | 5 | UniProt NCBI |
| EPB41L1 | Band 4.1-like protein 1 (Erythrocyte membrane protein band 4.1-like 1) (Neuronal protein 4.1) (4.1N) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:760 | 4.09448956317e-05 | 0.4 | ACIN1 RNPS1 | Apoptosis- and splicing-associated protein complex (ASAP-L), SAP18, RNPS1, Acinus-L |
| CORUM:351 | 0.0011586928604 | 0.6 | RNPS1 CWC22 ACIN1 | Spliceosome |
| WP:WP4148 | 0.00389862536801 | 0.4 | EPB41L2 EPB41L1 | Splicing factor NOVA regulated synaptic proteins |
| REAC:R-HSA-72163 | 0.00407681863898 | 0.6 | RNPS1 CWC22 ACIN1 | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.00451677062682 | 0.6 | RNPS1 CWC22 ACIN1 | mRNA Splicing |
| REAC:R-HSA-72203 | 0.0102904130445 | 0.6 | RNPS1 CWC22 ACIN1 | Processing of Capped Intron-Containing Pre-mRNA |
| REAC:R-HSA-6794361 | 0.0156388304105 | 0.4 | EPB41L2 EPB41L1 | Neurexins and neuroligins |
| KEGG:03015 | 0.0183886697314 | 0.4 | ACIN1 RNPS1 | mRNA surveillance pathway |
| KEGG:03013 | 0.0226459969921 | 0.4 | ACIN1 RNPS1 | Nucleocytoplasmic transport |
| GO:0061574 | 0.0280843539964 | 0.4 | ACIN1 RNPS1 | ASAP complex |
| REAC:R-HSA-6794362 | 0.0363707033179 | 0.4 | EPB41L2 EPB41L1 | Protein-protein interactions at synapses |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| EPB41L2 | EPB41L1 | 0.999 | 0.076 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM |
| CWC22 | EPB41L2 | 0.998 | 0.066 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| ACIN1 | RNPS1 | 0.998 | 0.92 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction |
| CWC22 | RNPS1 | 0.996 | 0.318 | bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 fraction |
| RNPS1 | EPB41L1 | 0.989 | 0.078 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| ACIN1 | EPB41L1 | 0.983 | 0.064 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| EPB41L2 | ACIN1 | 0.973 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction |
| EPB41L2 | RNPS1 | 0.967 | 0.068 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM |
| CWC22 | ACIN1 | 0.964 | 0.304 | bioplex_WMM bioplex3_WMM youn_WMM fraction treiber_WMM |
| CWC22 | EPB41L1 | 0.962 | 0.038 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes