hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00411.1
Complex Portal: CPX-15756
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PHF12 | PHD finger protein 12 (PHD factor 1) (Pf1) | 5 | UniProt NCBI |
| EMSY | BRCA2-interacting transcriptional repressor EMSY | 5 | UniProt NCBI |
| KDM5A | Lysine-specific demethylase 5A (EC 1.14.11.67) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2) ([histone H3]-trimethyl-L-lysine(4) demethylase 5A) | 5 | UniProt NCBI |
| MORF4L1 | Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (MRG15) (Protein MSL3-1) (Transcription factor-like protein MRG15) | 5 | UniProt NCBI |
| SIN3B | Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b) | 5 | UniProt NCBI |
| MORF4L2 | Mortality factor 4-like protein 2 (MORF-related gene X protein) (Protein MSL3-2) (Transcription factor-like protein MRGX) | 5 | UniProt NCBI |
| GATAD1 | GATA zinc finger domain-containing protein 1 (Ocular development-associated gene protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:528 | 0.00178994736007 | 0.333333333333 | MORF4L1 MORF4L2 | NuA4/Tip60-HAT complex |
| CORUM:529 | 0.00204528068441 | 0.333333333333 | MORF4L1 MORF4L2 | NuA4/Tip60-HAT complex |
| KEGG:03082 | 0.0382199966286 | 0.333333333333 | MORF4L1 MORF4L2 | ATP-dependent chromatin remodeling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PHF12 | GATAD1 | 1.0 | 0.168 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 | |
| KDM5A | GATAD1 | 1.0 | 0.192 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 | |
| EMSY | GATAD1 | 1.0 | 0.094 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 | |
| SIN3B | GATAD1 | 1.0 | 0.216 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 | |
| PHF12 | KDM5A | 1.0 | 0.294 | hein_WMM bioplex_WMM bioplex3_WMM hein () | |
| MORF4L1 | MORF4L2 | 0.999 | 0.144 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| PHF12 | SIN3B | 0.999 | 0.444 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () | |
| EMSY | SIN3B | 0.999 | 0.204 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM | |
| PHF12 | EMSY | 0.999 | 0.646 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () | |
| EMSY | KDM5A | 0.999 | 0.174 | hein_WMM bioplex_WMM bioplex3_WMM hein () | |
| KDM5A | SIN3B | 0.998 | 0.324 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM hein () | |
| MORF4L1 | GATAD1 | 0.998 | 0.114 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 | |
| PHF12 | MORF4L1 | 0.998 | 0.044 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () | |
| KDM5A | MORF4L1 | 0.993 | 0.132 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| EMSY | MORF4L1 | 0.992 | 0.026 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| MORF4L1 | SIN3B | 0.983 | 0.142 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM | |
| MORF4L2 | GATAD1 | 0.964 | 0.162 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PHF12 | MORF4L2 | 0.935 | 0.146 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () | |
| KDM5A | MORF4L2 | 0.623 | 0.09 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| SIN3B | MORF4L2 | 0.567 | 0.096 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM gupta_WMM | |
| EMSY | MORF4L2 | 0.407 | 0.036 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes