hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00437.1
Complex Portal: CPX-21824
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CCS | Copper chaperone for superoxide dismutase (Superoxide dismutase copper chaperone) | 5 | UniProt NCBI |
| SOD1 | Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) (Superoxide dismutase 1) (hSod1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2447 | 0.00022473634564 | 1.0 | SOD1 CCS | Amyotrophic lateral sclerosis ALS |
| WP:WP3286 | 0.000402652619272 | 1.0 | SOD1 CCS | Copper homeostasis |
| REAC:R-HSA-3299685 | 0.000645911942305 | 1.0 | SOD1 CCS | Detoxification of Reactive Oxygen Species |
| KEGG:05014 | 0.00850662183301 | 1.0 | SOD1 CCS | Amyotrophic lateral sclerosis |
| KEGG:05022 | 0.0138982457502 | 1.0 | SOD1 CCS | Pathways of neurodegeneration - multiple diseases |
| REAC:R-HSA-9711123 | 0.0284560094582 | 1.0 | SOD1 CCS | Cellular response to chemical stress |
| GO:0019430 | 0.0365196561665 | 1.0 | SOD1 CCS | removal of superoxide radicals |
| GO:0000303 | 0.0426062655276 | 1.0 | SOD1 CCS | response to superoxide |
| GO:0071450 | 0.0426062655276 | 1.0 | SOD1 CCS | cellular response to oxygen radical |
| GO:0071451 | 0.0426062655276 | 1.0 | SOD1 CCS | cellular response to superoxide |
| GO:0000305 | 0.0491610756088 | 1.0 | SOD1 CCS | response to oxygen radical |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CCS | SOD1 | 0.999 | 0.098 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM hein () bioplex3_HCT116 fraction |
Related Complexes
| Genename | Complexes |
|---|---|
| CCS | huMAP3_00437.1 huMAP3_14575.1 huMAP3_15334.1 |
| SOD1 | huMAP3_00437.1 huMAP3_15334.1 |