hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00465.1
Complex Portal: CPX-24455
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ASAH1 | Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (EC 3.5.1.-) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta] | 5 | UniProt NCBI |
| ARG1 | Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase) | 5 | UniProt NCBI |
| HAL | Histidine ammonia-lyase (Histidase) (EC 4.3.1.3) | 4 | UniProt NCBI |
| ECM1 | Extracellular matrix protein 1 (Secretory component p85) | 5 | UniProt NCBI |
| ALOX12B | Arachidonate 12-lipoxygenase, 12R-type (12R-LOX) (12R-lipoxygenase) (EC 1.13.11.-) (Epidermis-type lipoxygenase 12) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0461401 | 0.000136023075657 | 0.6 | HAL ECM1 ALOX12B | skin 1; cells in corneal layer[>=Low] |
| HPA:0471401 | 0.000511112498752 | 0.6 | HAL ECM1 ALOX12B | skin 2; cells in corneal layer[>=Low] |
| HPA:0461402 | 0.0115492947595 | 0.4 | ECM1 ALOX12B | skin 1; cells in corneal layer[>=Medium] |
| KEGG:01100 | 0.0139298332568 | 0.8 | ALOX12B ARG1 ASAH1 HAL | Metabolic pathways |
| WP:WP3925 | 0.0197951791935 | 0.4 | ARG1 HAL | Amino acid metabolism |
| HPA:0471402 | 0.0235407341342 | 0.4 | ECM1 ALOX12B | skin 2; cells in corneal layer[>=Medium] |
| HP:0033100 | 0.0358235710582 | 0.4 | ARG1 HAL | Increased proteinogenic amino acid level in urine |
| CORUM:7098 | 0.0498708842806 | 0.2 | ASAH1 | ASAH1-NR5A1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ECM1 | ALOX12B | 0.995 | 0.08 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| ARG1 | ECM1 | 0.991 | 0.182 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | |
| HAL | ALOX12B | 0.989 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | ||
| HAL | ECM1 | 0.986 | bioplex_WMM bioplex3_WMM boldt boldt_WMM treiber_WMM WMM_only | ||
| ARG1 | ALOX12B | 0.983 | 0.154 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| ARG1 | HAL | 0.979 | bioplex_WMM bioplex3_WMM boldt fraction boldt_WMM treiber_WMM | ||
| ASAH1 | ALOX12B | 0.977 | 0.07 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| ASAH1 | ECM1 | 0.883 | 0.074 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| ASAH1 | ARG1 | 0.229 | 0.166 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| ASAH1 | HAL | 0.168 | bioplex_WMM bioplex3_WMM boldt fraction boldt_WMM |
Related Complexes