hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00479.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NOTCH3 | Neurogenic locus notch homolog protein 3 (Notch 3) [Cleaved into: Notch 3 extracellular truncation; Notch 3 intracellular domain] | 5 | UniProt NCBI |
| DLK2 | Protein delta homolog 2 (DLK-2) (Epidermal growth factor-like protein 9) (EGF-like protein 9) | 4 | UniProt NCBI |
| WNT10A | Protein Wnt-10a | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3845 | 0.000193548942551 | 0.666666666667 | NOTCH3 DLK2 | Canonical and non canonical Notch signaling |
| WP:WP4787 | 0.00580814363334 | 0.666666666667 | WNT10A NOTCH3 | Osteoblast differentiation and related diseases |
| KEGG:05224 | 0.00607289882977 | 0.666666666667 | WNT10A NOTCH3 | Breast cancer |
| WP:WP4239 | 0.00973561742608 | 0.666666666667 | WNT10A NOTCH3 | Epithelial to mesenchymal transition in colorectal cancer |
| WP:WP4262 | 0.00988379918205 | 0.666666666667 | WNT10A NOTCH3 | Breast cancer pathway |
| KEGG:05165 | 0.0324411425615 | 0.666666666667 | WNT10A NOTCH3 | Human papillomavirus infection |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| NOTCH3 | WNT10A | 0.987 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| NOTCH3 | DLK2 | 0.956 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes