hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00484.1
Complex Portal: CPX-24284
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| AHSG | Alpha-2-HS-glycoprotein (Alpha-2-Z-globulin) (Ba-alpha-2-glycoprotein) (Fetuin-A) [Cleaved into: Alpha-2-HS-glycoprotein chain A; Alpha-2-HS-glycoprotein chain B] | 5 | UniProt NCBI |
| C4A | Complement C4-A (Acidic complement C4) (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2) [Cleaved into: Complement C4 beta chain; Complement C4-A alpha chain; C4a anaphylatoxin; C4b-A; C4d-A; Complement C4 gamma chain] | 5 | UniProt NCBI |
| ORM1 | Alpha-1-acid glycoprotein 1 (AGP 1) (Orosomucoid-1) (OMD 1) | 5 | UniProt NCBI |
| APOA4 | Apolipoprotein A-IV (Apo-AIV) (ApoA-IV) (Apolipoprotein A4) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0072562 | 0.000103177746529 | 1.0 | APOA4 ORM1 AHSG C4A | blood microparticle |
| REAC:R-HSA-8957275 | 0.0380580405855 | 0.5 | AHSG C4A | Post-translational protein phosphorylation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| AHSG | ORM1 | 0.984 | 0.282 |
mutually_exclusive (O43240)
|
bioplex_WMM bioplex3_WMM WMM_only |
| ORM1 | APOA4 | 0.977 | 0.406 | bioplex_WMM bioplex3_WMM WMM_only | |
| AHSG | APOA4 | 0.977 | 0.138 |
structurally_consistent (dimer)
|
bioplex_WMM bioplex3_WMM WMM_only |
| C4A | ORM1 | 0.966 | 0.492 | bioplex_WMM bioplex3_WMM WMM_only | |
| AHSG | C4A | 0.946 | 0.31 | bioplex_WMM bioplex3_WMM WMM_only | |
| C4A | APOA4 | 0.617 | 0.46 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes