hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00490.1
Complex Portal: CPX-12145
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NSUN4 | 5-methylcytosine rRNA methyltransferase NSUN4 (EC 2.1.1.-) (5-methylcytosine tRNA methyltransferase NSUN4) (EC 2.1.1.-) (NOL1/NOP2/Sun domain family member 4) | 5 | UniProt NCBI |
| MYEF2 | Myelin expression factor 2 (MEF-2) (MyEF-2) (MST156) | 5 | UniProt NCBI |
| MTERF4 | Transcription termination factor 4, mitochondrial (Mitochondrial transcription termination factor 4) (mTERF domain-containing protein 2) [Cleaved into: mTERF domain-containing protein 2 processed] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6793080 | 0.000102258192243 | 0.666666666667 | NSUN4 MTERF4 | rRNA modification in the mitochondrion |
| REAC:R-HSA-8868766 | 0.000306718584473 | 0.666666666667 | NSUN4 MTERF4 | rRNA processing in the mitochondrion |
| WP:WP1559 | 0.0496447587094 | 0.333333333333 | MYEF2 | Transcription factors regulate miRNAs related to cardiac hypertrophy |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NSUN4 | MTERF4 | 0.979 | 0.35 |
structurally_consistent (dimer)
|
bioplex_WMM bioplex3_WMM WMM_only |
| NSUN4 | MYEF2 | 0.97 | 0.024 | hein_WMM bioplex_WMM bioplex3_WMM hein () | |
| MYEF2 | MTERF4 | 0.059 | 0.05 | bioplex3_WMM WMM_only |
Related Complexes