hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00504.1
Complex Portal: CPX-23244
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SPATA31D3 | Spermatogenesis-associated protein 31D3 (Protein FAM75D3) | 2 | UniProt NCBI |
| MICB | MHC class I polypeptide-related sequence B (MIC-B) | 5 | UniProt NCBI |
| MICA | MHC class I polypeptide-related sequence A (MIC-A) | 5 | UniProt NCBI |
| ROM1 | Rod outer segment membrane protein 1 (ROSP1) (Tetraspanin-23) (Tspan-23) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5092 | 0.000764539714508 | 0.5 | MICB MICA | Interactions of natural killer cells in pancreatic cancer |
| MIRNA:hcmv-miR-UL112-3p | 0.0028092043205 | 0.5 | MICB MICA | hcmv-miR-UL112-3p |
| KEGG:04650 | 0.014619629343 | 0.5 | MICB MICA | Natural killer cell mediated cytotoxicity |
| KEGG:05167 | 0.0346546128597 | 0.5 | MICB MICA | Kaposi sarcoma-associated herpesvirus infection |
| CORUM:1772 | 0.049938562206 | 0.25 | MICB | MICB-KLRK1-HCST complex |
| CORUM:1774 | 0.049938562206 | 0.25 | MICA | MICA-KLRK1-HCST complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MICB | MICA | 0.987 | 0.1 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MICA | ROM1 | 0.977 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SPATA31D3 | MICA | 0.976 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| SPATA31D3 | MICB | 0.189 | bioplex3_WMM WMM_only |
Related Complexes