hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00519.1
Complex Portal: CPX-23958
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LIPA | Lysosomal acid lipase/cholesteryl ester hydrolase (Acid cholesteryl ester hydrolase) (LAL) (EC 3.1.1.13) (Cholesteryl esterase) (Lipase A) (Sterol esterase) | 5 | UniProt NCBI |
| GAL3ST2 | Galactose-3-O-sulfotransferase 2 (Gal3ST-2) (EC 2.8.2.-) (Beta-galactose-3-O-sulfotransferase 2) (Gal-beta-1, 3-GalNAc 3'-sulfotransferase 2) (Glycoprotein beta-Gal 3'-sulfotransferase 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00100 | 0.0379931878772 | 0.5 | LIPA | Steroid biosynthesis |
| WP:WP136 | 0.0435328773163 | 0.5 | LIPA | Phase I biotransformations non P450 |
| HP:0031205 | 0.0499436884913 | 0.5 | LIPA | Reduced lysosomal acid lipase activity |
| HP:0034029 | 0.0499436884913 | 0.5 | LIPA | Hepatic foam cells |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| LIPA | GAL3ST2 | 0.971 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| LIPA | huMAP3_00519.1 huMAP3_14136.1 huMAP3_15307.1 |
| GAL3ST2 | huMAP3_00519.1 huMAP3_12748.1 huMAP3_14123.1 huMAP3_14136.1 |