hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00531.1
Complex Portal: CPX-11176
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FAM83G | Protein FAM83G (Protein associated with SMAD1) | 5 | UniProt NCBI |
| EML3 | Echinoderm microtubule-associated protein-like 3 (EMAP-3) | 5 | UniProt NCBI |
| PARD3 | Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha) | 5 | UniProt NCBI |
| HDAC4 | Histone deacetylase 4 (HD4) (EC 3.5.1.98) | 5 | UniProt NCBI |
| KIF1B | Kinesin-like protein KIF1B (Klp) | 5 | UniProt NCBI |
| RASSF8 | Ras association domain-containing protein 8 (Carcinoma-associated protein HOJ-1) | 4 | UniProt NCBI |
| HDAC7 | Histone deacetylase 7 (HD7) (EC 3.5.1.98) (Histone deacetylase 7A) (HD7a) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP3996 | 0.00669310065721 | 0.285714285714 | HDAC4 HDAC7 | Ethanol effects on histone modifications |
| WP:WP3414 | 0.00718724508234 | 0.285714285714 | HDAC4 HDAC7 | Initiation of transcription and translation elongation at the HIV 1 LTR |
| REAC:R-HSA-350054 | 0.0087631788483 | 0.285714285714 | HDAC4 HDAC7 | Notch-HLH transcription pathway |
| WP:WP2795 | 0.0151967459334 | 0.285714285714 | HDAC4 HDAC7 | Cardiac hypertrophic response |
| REAC:R-HSA-2122947 | 0.0294686169459 | 0.285714285714 | HDAC4 HDAC7 | NOTCH1 Intracellular Domain Regulates Transcription |
| REAC:R-HSA-2894862 | 0.0407752524289 | 0.285714285714 | HDAC4 HDAC7 | Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants |
| REAC:R-HSA-2644606 | 0.0407752524289 | 0.285714285714 | HDAC4 HDAC7 | Constitutive Signaling by NOTCH1 PEST Domain Mutants |
| REAC:R-HSA-2894858 | 0.0407752524289 | 0.285714285714 | HDAC4 HDAC7 | Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer |
| REAC:R-HSA-2644602 | 0.0407752524289 | 0.285714285714 | HDAC4 HDAC7 | Signaling by NOTCH1 PEST Domain Mutants in Cancer |
| REAC:R-HSA-2644603 | 0.0407752524289 | 0.285714285714 | HDAC4 HDAC7 | Signaling by NOTCH1 in Cancer |
| WP:WP1544 | 0.0411525882545 | 0.285714285714 | HDAC4 HDAC7 | MicroRNAs in cardiomyocyte hypertrophy |
| WP:WP2064 | 0.0473257570206 | 0.285714285714 | HDAC4 HDAC7 | Neural crest differentiation |
| CORUM:57 | 0.0499958217778 | 0.142857142857 | HDAC4 | HDAC4-ERK2 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PARD3 | RASSF8 | 1.0 | 0.116 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 gupta_WMM boldt_WMM | |
| FAM83G | HDAC7 | 0.987 | 0.066 | hein_WMM bioplex3_WMM WMM_only | |
| FAM83G | HDAC4 | 0.987 | 0.07 | hein_WMM bioplex3_WMM WMM_only | |
| HDAC4 | HDAC7 | 0.985 | 0.078 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| EML3 | HDAC4 | 0.984 | 0.08 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| EML3 | HDAC7 | 0.984 | 0.1 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| FAM83G | PARD3 | 0.984 | 0.062 | hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| HDAC4 | RASSF8 | 0.983 | 0.126 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| HDAC4 | KIF1B | 0.981 | 0.116 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| KIF1B | HDAC7 | 0.981 | 0.096 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| PARD3 | HDAC4 | 0.98 | 0.106 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| PARD3 | HDAC7 | 0.98 | 0.084 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| FAM83G | EML3 | 0.979 | 0.05 | hein_WMM bioplex3_WMM WMM_only | |
| RASSF8 | HDAC7 | 0.978 | 0.104 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| FAM83G | RASSF8 | 0.956 | 0.074 | hein_WMM bioplex3_WMM gupta_WMM WMM_only | |
| FAM83G | KIF1B | 0.919 | 0.112 | hein_WMM bioplex3_WMM gupta_WMM WMM_only | |
| EML3 | PARD3 | 0.734 | 0.04200968523 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| EML3 | RASSF8 | 0.539 | 0.074 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| KIF1B | RASSF8 | 0.391 | 0.164 | hein_WMM youn () bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only | |
| EML3 | KIF1B | 0.362 | 0.092 | hein_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| PARD3 | KIF1B | 0.304 | 0.078 | hein_WMM youn () bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only |
Related Complexes