hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00548.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
DENND6B | Protein DENND6B (DENN domain-containing protein 6B) | 3 | UniProt   NCBI |
RPS6KC1 | Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein) | 5 | UniProt   NCBI |
DENND6A | Protein DENND6A (DENN domain-containing protein 6A) | 4 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-8876198 | 0.0220121799777 | 0.666666666667 | DENND6B DENND6A | RAB GEFs exchange GTP for GDP on RABs |
  REAC:R-HSA-9007101 | 0.0392065258044 | 0.666666666667 | DENND6B DENND6A | Rab regulation of trafficking |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 RPS6KC1 |  DENND6A | 0.995 | 0.108           | hein_WMM     bioplex3_HEK293     bioplex3_WMM     hein ()     |
 DENND6B |  DENND6A | 0.958 |            | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 DENND6B |  RPS6KC1 | 0.415 |            | bioplex3_WMM     WMM_only     |
Related Complexes
Genename | Complexes |
---|---|
DENND6B | huMAP3_00548.1 huMAP3_13196.1 huMAP3_13618.1 |
RPS6KC1 | huMAP3_00548.1 huMAP3_06655.1 huMAP3_13196.1 huMAP3_13618.1 |
DENND6A | huMAP3_00548.1 huMAP3_06655.1 huMAP3_07321.1 huMAP3_13196.1 huMAP3_13618.1 |