hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00561.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| IDH1 | Isocitrate dehydrogenase [NADP] cytoplasmic (IDH) (IDH1) (EC 1.1.1.42) (Cytosolic NADP-isocitrate dehydrogenase) (IDPc) (NADP(+)-specific ICDH) (Oxalosuccinate decarboxylase) | 5 | UniProt NCBI |
| ARHGDIA | Rho GDP-dissociation inhibitor 1 (Rho GDI 1) (Rho-GDI alpha) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2978092 | 0.0249718442457 | 0.5 | IDH1 | Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate |
| REAC:R-HSA-389542 | 0.0249718442457 | 0.5 | IDH1 | NADPH regeneration |
| CORUM:404 | 0.0249718442457 | 0.5 | IDH1 | Isocitrate dehydrogenase [NADP], cytoplasmic |
| WP:WP3585 | 0.0435328773163 | 0.5 | IDH1 | Cytosine methylation |
| REAC:R-HSA-209563 | 0.0499419797295 | 0.5 | ARHGDIA | Axonal growth stimulation |
| HP:0004820 | 0.0499436884913 | 0.5 | IDH1 | Acute myelomonocytic leukemia |
| HP:0011681 | 0.0499436884913 | 0.5 | IDH1 | Subarterial ventricular septal defect |
| HP:0030294 | 0.0499436884913 | 0.5 | IDH1 | Metaphyseal chondromatosis of tibia |
| HP:0030295 | 0.0499436884913 | 0.5 | IDH1 | Metaphyseal chondromatosis of femur |
| HP:0030296 | 0.0499436884913 | 0.5 | IDH1 | Metaphyseal chondromatosis of radius |
| HP:0030297 | 0.0499436884913 | 0.5 | IDH1 | Metaphyseal chondromatosis of ulna |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| IDH1 | ARHGDIA | 0.959 | 0.22 | bioplex_WMM Guru bioplex3_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| IDH1 | huMAP3_00561.1 huMAP3_01475.1 huMAP3_02650.1 huMAP3_09400.1 huMAP3_10900.1 huMAP3_12355.1 |
| ARHGDIA | huMAP3_00561.1 huMAP3_01475.1 huMAP3_09400.1 huMAP3_12355.1 huMAP3_12504.1 huMAP3_12800.1 |