hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00592.1
Complex Portal: CPX-12211
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MMACHC | Cyanocobalamin reductase / alkylcobalamin dealkylase (Alkylcobalamin:glutathione S-alkyltransferase) (EC 2.5.1.151) (CblC) (Cyanocobalamin reductase (cyanide-eliminating)) (EC 1.16.1.6) (Methylmalonic aciduria and homocystinuria type C protein) (MMACHC) | 5 | UniProt NCBI |
| BNIP5 | Protein BNIP5 | 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3359474 | 0.0249718442457 | 0.5 | MMACHC | Defective MMACHC causes MAHCC |
| KEGG:04977 | 0.0474849820587 | 0.5 | MMACHC | Vitamin digestion and absorption |
| REAC:R-HSA-3359473 | 0.0499419797295 | 0.5 | MMACHC | Defective MMADHC causes MMAHCD |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| MMACHC | BNIP5 | 0.96 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| MMACHC | huMAP3_00592.1 huMAP3_04091.1 huMAP3_11460.1 |
| BNIP5 | huMAP3_00592.1 huMAP3_04091.1 huMAP3_11337.1 huMAP3_11460.1 huMAP3_13492.1 |