hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00621.1
Confidence: Extremely High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
PDE3A | cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (EC 3.1.4.17) (Cyclic GMP-inhibited phosphodiesterase A) (CGI-PDE A) (cGMP-inhibited cAMP phosphodiesterase) (cGI-PDE) | 5 | UniProt   NCBI |
XIRP2 | Xin actin-binding repeat-containing protein 2 (Beta-xin) (Cardiomyopathy-associated protein 3) (Xeplin) | 5 | UniProt   NCBI |
PDE3B | cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (EC 3.1.4.17) (CGIPDE1) (CGIP1) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  WP:WP4222 | 0.00079501095268 | 0.666666666667 | PDE3A PDE3B | Phosphodiesterases in neuronal function |
  KEGG:04924 | 0.00085927513712 | 0.666666666667 | PDE3A PDE3B | Renin secretion |
  GO:0004119 | 0.00140460216025 | 0.666666666667 | PDE3A PDE3B | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity |
  KEGG:05032 | 0.00173372250929 | 0.666666666667 | PDE3A PDE3B | Morphine addiction |
  KEGG:00230 | 0.00361241039138 | 0.666666666667 | PDE3A PDE3B | Purine metabolism |
  KEGG:04022 | 0.00588292524774 | 0.666666666667 | PDE3A PDE3B | cGMP-PKG signaling pathway |
  KEGG:04024 | 0.00940070336911 | 0.666666666667 | PDE3A PDE3B | cAMP signaling pathway |
  REAC:R-HSA-418555 | 0.0284248695791 | 0.666666666667 | PDE3A PDE3B | G alpha (s) signalling events |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 PDE3A |  PDE3B | 0.994 | 0.26           | bioplex3_HEK293     bioplex3_WMM     bioplex3_HCT116     WMM_only     |
 PDE3A |  XIRP2 | 0.987 | 0.152           | bioplex3_HEK293     bioplex3_WMM     WMM_only     |
 XIRP2 |  PDE3B | 0.051 | 0.146           | bioplex3_WMM     WMM_only     |
Related Complexes
Genename | Complexes |
---|---|
PDE3A | huMAP3_00621.1 huMAP3_01638.1 huMAP3_07442.1 huMAP3_12808.1 |
XIRP2 | huMAP3_00621.1 huMAP3_01638.1 huMAP3_12808.1 |
PDE3B | huMAP3_00621.1 huMAP3_07442.1 huMAP3_09065.1 huMAP3_10409.1 huMAP3_15113.1 |