hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00628.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| INTS13 | Integrator complex subunit 13 (Cell cycle regulator Mat89Bb homolog) (Germ cell tumor 1) (Protein asunder homolog) (Sarcoma antigen NY-SAR-95) | 5 | UniProt NCBI |
| INTS14 | Integrator complex subunit 14 (von Willebrand factor A domain-containing protein 9) | 4 | UniProt NCBI |
| INTS10 | Integrator complex subunit 10 (Int10) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5345 | 3.88479998273e-06 | 1.0 | INTS13 INTS10 INTS14 | 1p36 copy number variation syndrome |
| REAC:R-HSA-6807505 | 2.78281516981e-05 | 1.0 | INTS13 INTS10 INTS14 | RNA polymerase II transcribes snRNA genes |
| GO:0032039 | 9.31403198031e-05 | 1.0 | INTS13 INTS10 INTS14 | integrator complex |
| GO:0016180 | 0.000249912106799 | 1.0 | INTS13 INTS10 INTS14 | snRNA processing |
| GO:0016073 | 0.00212425290779 | 1.0 | INTS13 INTS10 INTS14 | snRNA metabolic process |
| GO:0034243 | 0.00731242824493 | 1.0 | INTS13 INTS10 INTS14 | regulation of transcription elongation by RNA polymerase II |
| GO:0032784 | 0.0133044554856 | 1.0 | INTS13 INTS10 INTS14 | regulation of DNA-templated transcription elongation |
| GO:0006368 | 0.0150763323228 | 1.0 | INTS13 INTS10 INTS14 | transcription elongation by RNA polymerase II |
| GO:0006354 | 0.0243625856112 | 1.0 | INTS13 INTS10 INTS14 | DNA-templated transcription elongation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| INTS14 | INTS10 | 0.999 | 0.12 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () |
| INTS13 | INTS10 | 0.997 | 0.184 |
structurally_consistent (Q96SY0)
structurally_consistent (dimer) |
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| INTS13 | INTS14 | 0.997 | 0.826 |
structurally_consistent (dimer)
|
hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () Malo fraction |
Related Complexes
| Genename | Complexes |
|---|---|
| INTS13 | huMAP3_00628.1 huMAP3_03028.1 huMAP3_11853.1 huMAP3_12564.1 huMAP3_14818.1 huMAP3_15286.1 |
| INTS14 | huMAP3_00628.1 huMAP3_12564.1 huMAP3_15286.1 |
| INTS10 | huMAP3_00628.1 huMAP3_03028.1 huMAP3_11853.1 huMAP3_12564.1 huMAP3_14818.1 huMAP3_15286.1 |