hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00631.1
Complex Portal: CPX-13857
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| FCHO2 | F-BAR domain only protein 2 | 5 | UniProt NCBI |
| AP2M1 | AP-2 complex subunit mu (AP-2 mu chain) (Adaptin-mu2) (Adaptor protein complex AP-2 subunit mu) (Adaptor-related protein complex 2 subunit mu) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (HA2 50 kDa subunit) (Plasma membrane adaptor AP-2 50 kDa protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8856825 | 0.00746899761856 | 1.0 | FCHO2 AP2M1 | Cargo recognition for clathrin-mediated endocytosis |
| REAC:R-HSA-8856828 | 0.0152267759732 | 1.0 | FCHO2 AP2M1 | Clathrin-mediated endocytosis |
| REAC:R-HSA-164939 | 0.0499419797295 | 0.5 | AP2M1 | Nef mediated downregulation of CD28 cell surface expression |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| FCHO2 | AP2M1 | 0.987 | 0.104 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM |
Related Complexes