hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00636.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| UPK3BL2 | Uroplakin-3b-like protein 2 | 2 | UniProt NCBI |
| HGFAC | Hepatocyte growth factor activator (HGF activator) (HGFA) (EC 3.4.21.-) [Cleaved into: Hepatocyte growth factor activator short chain; Hepatocyte growth factor activator long chain] | 5 | UniProt NCBI |
| SLC35F5 | Solute carrier family 35 member F5 (Hepatitis C virus NS5A-transactivated protein 3) (HCV NS5A-transactivated protein 3) | 3 | UniProt NCBI |
| SPINT2 | Kunitz-type protease inhibitor 2 (Hepatocyte growth factor activator inhibitor type 2) (HAI-2) (Placental bikunin) | 5 | UniProt NCBI |
| ABCA3 | Phospholipid-transporting ATPase ABCA3 (EC 7.6.2.1) (ABC-C transporter) (ATP-binding cassette sub-family A member 3) (ATP-binding cassette transporter 3) (ATP-binding cassette 3) (Xenobiotic-transporting ATPase ABCA3) (EC 7.6.2.2) [Cleaved into: 150 Kda mature form] | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6806942 | 0.000227895019208 | 0.4 | HGFAC SPINT2 | MET Receptor Activation |
| REAC:R-HSA-6806834 | 0.035336387757 | 0.4 | HGFAC SPINT2 | Signaling by MET |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| HGFAC | SPINT2 | 0.998 | 0.068 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| SLC35F5 | SPINT2 | 0.975 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| UPK3BL2 | SPINT2 | 0.97 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| SPINT2 | ABCA3 | 0.952 | 0.136 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| SLC35F5 | ABCA3 | 0.813 | bioplex_WMM bioplex3_WMM WMM_only | |
| UPK3BL2 | ABCA3 | 0.622 | bioplex_WMM bioplex3_WMM WMM_only | |
| HGFAC | SLC35F5 | 0.3 | bioplex_WMM bioplex3_WMM WMM_only | |
| UPK3BL2 | SLC35F5 | 0.254 | bioplex_WMM bioplex3_WMM WMM_only | |
| UPK3BL2 | HGFAC | 0.037 | bioplex_WMM bioplex3_WMM WMM_only | |
| HGFAC | ABCA3 | 0.018 | 0.098 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes