hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00640.1
Complex Portal: CPX-13095
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| RIPK3 | Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3) | 5 | UniProt NCBI |
| EPHA3 | Ephrin type-A receptor 3 (EC 2.7.10.1) (EPH-like kinase 4) (EK4) (hEK4) (HEK) (Human embryo kinase) (Tyrosine-protein kinase TYRO4) (Tyrosine-protein kinase receptor ETK1) (Eph-like tyrosine kinase 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9686347 | 0.0374577663684 | 1.0 | RIPK3 | Microbial modulation of RIPK1-mediated regulated necrosis |
| REAC:R-HSA-9692913 | 0.0374577663684 | 1.0 | RIPK3 | SARS-CoV-1-mediated effects on programmed cell death |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RIPK3 | EPHA3 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| RIPK3 | huMAP3_00640.1 huMAP3_09714.1 |
| EPHA3 | huMAP3_00640.1 huMAP3_08682.1 huMAP3_09714.1 huMAP3_11581.1 huMAP3_12979.1 huMAP3_13758.1 huMAP3_13902.1 huMAP3_14399.1 huMAP3_14479.1 huMAP3_14909.1 |