hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00645.1
Complex Portal: CPX-13362
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CPEB2 | Cytoplasmic polyadenylation element-binding protein 2 (CPE-BP2) (CPE-binding protein 2) (hCPEB-2) | 5 | UniProt NCBI |
| CPEB4 | Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4) | 5 | UniProt NCBI |
| CPEB3 | Cytoplasmic polyadenylation element-binding protein 3 (CPE-BP3) (CPE-binding protein 3) (hCPEB-3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04914 | 4.62629936833e-06 | 1.0 | CPEB2 CPEB3 CPEB4 | Progesterone-mediated oocyte maturation |
| GO:2000766 | 8.07408345042e-06 | 1.0 | CPEB2 CPEB3 CPEB4 | negative regulation of cytoplasmic translation |
| KEGG:04114 | 9.51295867401e-06 | 1.0 | CPEB2 CPEB3 CPEB4 | Oocyte meiosis |
| GO:0000900 | 1.15344049292e-05 | 1.0 | CPEB2 CPEB3 CPEB4 | mRNA regulatory element binding translation repressor activity |
| GO:1990124 | 1.58598067776e-05 | 1.0 | CPEB2 CPEB3 CPEB4 | messenger ribonucleoprotein complex |
| GO:0030371 | 0.000249912106799 | 1.0 | CPEB2 CPEB3 CPEB4 | translation repressor activity |
| GO:2000765 | 0.000432059584639 | 1.0 | CPEB2 CPEB3 CPEB4 | regulation of cytoplasmic translation |
| GO:1900248 | 0.00140460216025 | 0.666666666667 | CPEB2 CPEB3 | negative regulation of cytoplasmic translational elongation |
| GO:1900247 | 0.00140460216025 | 0.666666666667 | CPEB2 CPEB3 | regulation of cytoplasmic translational elongation |
| MIRNA:ebv-miR-BART10-3p | 0.00252170927764 | 1.0 | CPEB2 CPEB3 CPEB4 | ebv-miR-BART10-3p |
| GO:0045900 | 0.00421361424067 | 0.666666666667 | CPEB2 CPEB3 | negative regulation of translational elongation |
| GO:0008135 | 0.00526161104852 | 1.0 | CPEB2 CPEB3 CPEB4 | translation factor activity, RNA binding |
| GO:0002182 | 0.00842684400117 | 0.666666666667 | CPEB2 CPEB3 | cytoplasmic translational elongation |
| GO:0043022 | 0.00915870199393 | 1.0 | CPEB2 CPEB3 CPEB4 | ribosome binding |
| GO:0090079 | 0.00949377645712 | 1.0 | CPEB2 CPEB3 CPEB4 | translation regulator activity, nucleic acid binding |
| GO:0003730 | 0.00949377645712 | 1.0 | CPEB2 CPEB3 CPEB4 | mRNA 3'-UTR binding |
| GO:0017148 | 0.0169989253844 | 1.0 | CPEB2 CPEB3 CPEB4 | negative regulation of translation |
| GO:0045182 | 0.0207446272651 | 1.0 | CPEB2 CPEB3 CPEB4 | translation regulator activity |
| GO:0034249 | 0.0276806494292 | 1.0 | CPEB2 CPEB3 CPEB4 | negative regulation of amide metabolic process |
| GO:0006448 | 0.0294899169624 | 0.666666666667 | CPEB2 CPEB3 | regulation of translational elongation |
| GO:0043021 | 0.0351938724399 | 1.0 | CPEB2 CPEB3 CPEB4 | ribonucleoprotein complex binding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CPEB2 | CPEB4 | 0.983 | 0.156 | bioplex3_HEK293 bioplex3_WMM youn_WMM WMM_only | |
| CPEB4 | CPEB3 | 0.978 | youn () bioplex3_HEK293 bioplex3_WMM youn_WMM WMM_only | ||
| CPEB2 | CPEB3 | 0.415 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| CPEB2 | huMAP3_00645.1 huMAP3_13048.1 huMAP3_13573.1 huMAP3_14535.1 |
| CPEB4 | huMAP3_00645.1 huMAP3_11793.1 huMAP3_13048.1 huMAP3_13573.1 huMAP3_14535.1 |
| CPEB3 | huMAP3_00645.1 huMAP3_13048.1 huMAP3_13573.1 |