hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_00657.1
Complex Portal: CPX-18201
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCNIP4 | Kv channel-interacting protein 4 (KChIP4) (A-type potassium channel modulatory protein 4) (Calsenilin-like protein) (Potassium channel-interacting protein 4) | 5 | UniProt NCBI |
| KCNIP2 | Kv channel-interacting protein 2 (KChIP2) (A-type potassium channel modulatory protein 2) (Cardiac voltage-gated potassium channel modulatory subunit) (Potassium channel-interacting protein 2) | 5 | UniProt NCBI |
| KCNIP1 | Kv channel-interacting protein 1 (KChIP1) (A-type potassium channel modulatory protein 1) (Potassium channel-interacting protein 1) (Vesicle APC-binding protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5576894 | 4.66602141148e-09 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | Phase 1 - inactivation of fast Na+ channels |
| REAC:R-HSA-5576891 | 4.60862934812e-05 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | Cardiac conduction |
| REAC:R-HSA-397014 | 0.000257237760415 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | Muscle contraction |
| GO:0015459 | 0.000524430944113 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | potassium channel regulator activity |
| GO:1901379 | 0.00225170808226 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | regulation of potassium ion transmembrane transport |
| GO:0008076 | 0.00238416149886 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | voltage-gated potassium channel complex |
| GO:0043266 | 0.00296587998745 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | regulation of potassium ion transport |
| GO:0034705 | 0.00345936027834 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | potassium channel complex |
| GO:0099106 | 0.013733631469 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | ion channel regulator activity |
| GO:0016247 | 0.0160184048454 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | channel regulator activity |
| GO:0141108 | 0.0160184048454 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | transporter regulator activity |
| CORUM:6650 | 0.0249718442456 | 0.333333333333 | KCNIP4 | KCND3-KCNIP4 complex |
| GO:0071805 | 0.0290879429506 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | potassium ion transmembrane transport |
| GO:0034703 | 0.0343879058955 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | cation channel complex |
| GO:0006813 | 0.0360123345897 | 1.0 | KCNIP1 KCNIP4 KCNIP2 | potassium ion transport |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| KCNIP2 | KCNIP1 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| KCNIP4 | KCNIP2 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| KCNIP4 | KCNIP1 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| KCNIP4 | huMAP3_00085.1 huMAP3_00657.1 huMAP3_01401.1 huMAP3_06786.1 huMAP3_08455.1 |
| KCNIP2 | huMAP3_00085.1 huMAP3_00657.1 huMAP3_08455.1 |
| KCNIP1 | huMAP3_00085.1 huMAP3_00657.1 huMAP3_03591.1 huMAP3_06786.1 huMAP3_08455.1 huMAP3_11462.1 |