hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00668.1
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TAF1C | TATA box-binding protein-associated factor RNA polymerase I subunit C (RNA polymerase I-specific TBP-associated factor 110 kDa) (TAFI110) (TATA box-binding protein-associated factor 1C) (TBP-associated factor 1C) (Transcription initiation factor SL1/TIF-IB subunit C) | 5 | UniProt NCBI |
| TAF1D | TATA box-binding protein-associated factor RNA polymerase I subunit D (RNA polymerase I-specific TBP-associated factor 41 kDa) (TAFI41) (TATA box-binding protein-associated factor 1D) (TBP-associated factor 1D) (Transcription initiation factor SL1/TIF-IB subunit D) | 5 | UniProt NCBI |
| TAF1B | TATA box-binding protein-associated factor RNA polymerase I subunit B (RNA polymerase I-specific TBP-associated factor 63 kDa) (TAFI63) (TATA box-binding protein-associated factor 1B) (TBP-associated factor 1B) (Transcription initiation factor SL1/TIF-IB subunit B) | 5 | UniProt NCBI |
| TAF1A | TATA box-binding protein-associated factor RNA polymerase I subunit A (RNA polymerase I-specific TBP-associated factor 48 kDa) (TAFI48) (TATA box-binding protein-associated factor 1A) (TBP-associated factor 1A) (Transcription factor SL1) (Transcription initiation factor SL1/TIF-IB subunit A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:5727 | 2.80628050973e-09 | 0.75 | TAF1C TAF1A TAF1B | TBP-TAF complex |
| REAC:R-HSA-73863 | 3.02163114855e-09 | 1.0 | TAF1B TAF1C TAF1A TAF1D | RNA Polymerase I Transcription Termination |
| REAC:R-HSA-73762 | 1.71286585035e-08 | 1.0 | TAF1B TAF1C TAF1A TAF1D | RNA Polymerase I Transcription Initiation |
| REAC:R-HSA-427359 | 3.52714096473e-08 | 1.0 | TAF1B TAF1C TAF1A TAF1D | SIRT1 negatively regulates rRNA expression |
| REAC:R-HSA-5250924 | 1.36981732435e-07 | 1.0 | TAF1B TAF1C TAF1A TAF1D | B-WICH complex positively regulates rRNA expression |
| REAC:R-HSA-73772 | 1.44287424832e-07 | 1.0 | TAF1B TAF1C TAF1A TAF1D | RNA Polymerase I Promoter Escape |
| REAC:R-HSA-5250913 | 2.8038653175e-07 | 1.0 | TAF1B TAF1C TAF1A TAF1D | Positive epigenetic regulation of rRNA expression |
| REAC:R-HSA-427413 | 2.92848155383e-07 | 1.0 | TAF1B TAF1C TAF1A TAF1D | NoRC negatively regulates rRNA expression |
| REAC:R-HSA-5250941 | 3.32733782576e-07 | 1.0 | TAF1B TAF1C TAF1A TAF1D | Negative epigenetic regulation of rRNA expression |
| REAC:R-HSA-73854 | 3.46892666941e-07 | 1.0 | TAF1B TAF1C TAF1A TAF1D | RNA Polymerase I Promoter Clearance |
| REAC:R-HSA-73864 | 3.6149867397e-07 | 1.0 | TAF1B TAF1C TAF1A TAF1D | RNA Polymerase I Transcription |
| REAC:R-HSA-212165 | 3.30250504016e-06 | 1.0 | TAF1B TAF1C TAF1A TAF1D | Epigenetic regulation of gene expression |
| REAC:R-HSA-74160 | 0.0112707156575 | 1.0 | TAF1B TAF1C TAF1A TAF1D | Gene expression (Transcription) |
| GO:0006360 | 0.0118300289699 | 0.75 | TAF1C TAF1A TAF1B | transcription by RNA polymerase I |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TAF1A | TAF1C | 0.998 | 0.178 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM |
| TAF1D | TAF1B | 0.998 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| TAF1A | TAF1B | 0.997 | 0.178 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM |
| TAF1A | TAF1D | 0.997 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM | ||
| TAF1C | TAF1B | 0.996 | 0.15 |
mutually_exclusive (Q15573)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM |
| TAF1C | TAF1D | 0.995 |
structurally_consistent (dimer)
|
hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction |
Related Complexes