hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_00678.1
Complex Portal: CPX-23240
Confidence: Extremely High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC7A11 | Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT) | 5 | UniProt NCBI |
| SLC35E1 | Solute carrier family 35 member E1 | 3 | UniProt NCBI |
| SLC39A7 | Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Really interesting new gene 5 protein) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2884 | 0.00700579973273 | 0.666666666667 | SLC7A11 SLC39A7 | NRF2 pathway |
| GO:0097707 | 0.0140440992017 | 0.666666666667 | SLC7A11 SLC39A7 | ferroptosis |
| GO:0110075 | 0.0140440992017 | 0.666666666667 | SLC7A11 SLC39A7 | regulation of ferroptosis |
| WP:WP2882 | 0.0351361093338 | 0.666666666667 | SLC7A11 SLC39A7 | Nuclear receptors meta pathway |
| WP:WP5213 | 0.0496447587094 | 0.333333333333 | SLC7A11 | Amino acid metabolism in triple negative breast cancer cells |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SLC7A11 | SLC35E1 | 0.983 | 0.07 | bioplex_WMM bioplex3_WMM boldt gupta_WMM boldt_WMM WMM_only | |
| SLC35E1 | SLC39A7 | 0.978 | 0.116 | hein_WMM bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only | |
| SLC7A11 | SLC39A7 | 0.089 | 0.038 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
Related Complexes